MAGB4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MAGB4_HUMAN
• UniProt AC: O15481
• Protein Name: Melanoma-associated antigen B4
• Gene Name: MAGEB4
• Organism: Homo sapiens (Human).
• Sequence Length: 346
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MPRGQKSKLRAREKRQRTRGQTQDLKVGQPTAAEKEESPSSSSSVLRDTASSSLAFGIPQEPQREPPTTSAAAAMSCTGSDKGDESQDEENASSSQASTSTERSLKDSLTRKTKMLVQFLLYKYKMKEPTTKAEMLKIISKKYKEHFPEIFRKVSQRTELVFGLALKEVNPTTHSYILVSMLGPNDGNQSSAWTLPRNGLLMPLLSVIFLNGNCAREEEIWEFLNMLGIYDGKRHLIFGEPRKLITQDLVQEKYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLEFLAKVNDTTPNNFPLLYEEALRDEEERAGARPRVAARRGTTAMTSAYSRATSSSSSQPM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	Phosphorylation	TAAEKEESPSSSSSV CHHHCCCCCCCCCHH	31.04	24719451
69	Phosphorylation	PQREPPTTSAAAAMS CCCCCCCCCHHHHHH	23.34	-
70	Phosphorylation	QREPPTTSAAAAMSC CCCCCCCCHHHHHHC	20.56	-
76	Phosphorylation	TSAAAAMSCTGSDKG CCHHHHHHCCCCCCC	12.10	28348404
78	Phosphorylation	AAAAMSCTGSDKGDE HHHHHHCCCCCCCCC	32.20	28348404
80	Phosphorylation	AAMSCTGSDKGDESQ HHHHCCCCCCCCCCC	20.28	28348404
86	Phosphorylation	GSDKGDESQDEENAS CCCCCCCCCCCHHHC	47.90	28348404
99	Phosphorylation	ASSSQASTSTERSLK HCCCCCCHHHHHHHH	42.56	-
101	Phosphorylation	SSQASTSTERSLKDS CCCCCHHHHHHHHHH	35.19	-
108	Phosphorylation	TERSLKDSLTRKTKM HHHHHHHHHHHHHHH	30.01	24719451
122	Phosphorylation	MLVQFLLYKYKMKEP HHHHHHHHHHCCCCC	17.89	19835603
124	Phosphorylation	VQFLLYKYKMKEPTT HHHHHHHHCCCCCCC	11.62	20049867
131	Phosphorylation	YKMKEPTTKAEMLKI HCCCCCCCHHHHHHH	38.68	-
143	Phosphorylation	LKIISKKYKEHFPEI HHHHHHHHHHHHHHH	25.91	29083192
242	Methylation	HLIFGEPRKLITQDL EEECCCCCHHHCHHH	41.95	24412083
242	Dimethylation	HLIFGEPRKLITQDL EEECCCCCHHHCHHH	41.95	-
282	Ubiquitination	RAHAETSKMKVLEFL CCCHHHCHHHHHHHH	50.59	23000965
284	Ubiquitination	HAETSKMKVLEFLAK CHHHCHHHHHHHHHH	47.61	23000965
328	Phosphorylation	VAARRGTTAMTSAYS HHHHCCCCHHHHHHH	19.77	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MAGB4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MAGB4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MAGB4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SPB1_HUMAN	FTSJ3	physical	16189514
ROCK1_HUMAN	ROCK1	physical	25416956
TENR_HUMAN	TNR	physical	25416956
KRT38_HUMAN	KRT38	physical	25416956
HGS_HUMAN	HGS	physical	25416956
MED21_HUMAN	MED21	physical	25416956
RUN3A_HUMAN	RUNDC3A	physical	25416956
KANK2_HUMAN	KANK2	physical	25416956
UBP25_HUMAN	USP25	physical	25416956
CC136_HUMAN	CCDC136	physical	25416956
USBP1_HUMAN	USHBP1	physical	25416956
LZTS2_HUMAN	LZTS2	physical	25416956
ZN341_HUMAN	ZNF341	physical	25416956
FER3L_HUMAN	FERD3L	physical	25416956
WDR62_HUMAN	WDR62	physical	25416956
MAGA1_HUMAN	MAGEA1	physical	26186194
KCC2D_HUMAN	CAMK2D	physical	26186194
BRX1_HUMAN	BRIX1	physical	26186194
ROCK1_HUMAN	ROCK1	physical	26186194
MAGA1_HUMAN	MAGEA1	physical	28514442
ROCK1_HUMAN	ROCK1	physical	28514442
C1QBP_HUMAN	C1QBP	physical	28514442
KCC2D_HUMAN	CAMK2D	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.