FER3L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FER3L_HUMAN
• UniProt AC: Q96RJ6
• Protein Name: Fer3-like protein
• Gene Name: FERD3L
• Organism: Homo sapiens (Human).
• Sequence Length: 166
• Subcellular Localization: Nucleus .
• Protein Description: Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins (By similarity)..
• Protein Sequence: MAAYPESCVDTTVLDFVADLSLASPRRPLLCDFAPGVSLGDPALALREGRPRRMARFEEGDPEEEECEVDQGDGEEEEEEERGRGVSLLGRPKRKRVITYAQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLESCEKKESG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
138	Phosphorylation	FAYEKRLSRIETLRL HHHHHHHHHHHHHHH	34.93	27174698

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FER3L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FER3L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FER3L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TFE2_HUMAN	TCF3	physical	28514442
HTF4_HUMAN	TCF12	physical	28514442
ITF2_HUMAN	TCF4	physical	28514442
UBP19_HUMAN	USP19	physical	28514442
HEXI2_HUMAN	HEXIM2	physical	28514442
NEST_HUMAN	NES	physical	28514442
DMWD_HUMAN	DMWD	physical	28514442
COR2A_HUMAN	CORO2A	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.