LDH_DROME - dbPTM
LDH_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LDH_DROME
UniProt AC Q95028
Protein Name L-lactate dehydrogenase
Gene Name ImpL3
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 332
Subcellular Localization Cytoplasm.
Protein Description
Protein Sequence MAAIKDSLLAQVAEVLPSSGHKVTIVGIGQVGMASAFSILAQNVSKEVCLIDVCADKLQGELMDLQHGSNFLKNPQITASTDFAASANSRLCIVTAGVRQKEGESRLSLVQRNTDILKNIIPKLVEYSPDTILLMVSNPVDIMTYVAWKLSGLPKNRVIGSGTNLDSSRFRFLMSQRLGVAPTSCHGWIIGEHGDSSVPVWSGVNIAGVRLRELNPILGTGEDPEKWNELHKQVVDSAYEVIKLKGYTSWAIGLSTASLASAILRNTSSVAAVSTSVLGEHGIDKDVFLSLPCVLNANGVTSVVKQILTPTEVEQLQKSANIMSDVQAGLKF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
18PhosphorylationQVAEVLPSSGHKVTI
HHHHHCCCCCCEEEE
44.8021082442
19PhosphorylationVAEVLPSSGHKVTIV
HHHHCCCCCCEEEEE
42.8721082442
108PhosphorylationKEGESRLSLVQRNTD
CCCCCHHHHHHHCHH
25.9422817900
290PhosphorylationIDKDVFLSLPCVLNA
CCCCCEECCCEEECC
20.8522817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LDH_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LDH_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LDH_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ATC1_DROMECa-P60Aphysical
22036573
ARF1_DROMEArf79Fphysical
22036573
ACADM_DROMECG12262physical
22036573
ATPG_DROMEATPsyn-gammaphysical
22036573
TCPG_DROMECctgammaphysical
22036573
DX39B_DROMEHel25Ephysical
22036573
VDAC_DROMEporinphysical
22036573
OST48_DROMEOst48physical
22036573
RAS3_DROMERphysical
22036573
KPYK_DROMEPyKphysical
22036573
ATPA_DROMEblwphysical
22036573
ARL8_DROMEGiephysical
22036573
ERD2_DROMEKdelRphysical
22036573
KRH2_DROMEKr-h2physical
22036573
QCR9_DROMEoxphysical
22036573
PRS8_DROMERpt6physical
22036573
GALE_DROMEGalephysical
22036573
ARF2_DROMEArf102Fphysical
22036573

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LDH_DROME

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Related Literatures of Post-Translational Modification

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