GTR4_HUMAN - dbPTM
GTR4_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GTR4_HUMAN
UniProt AC P14672
Protein Name Solute carrier family 2, facilitated glucose transporter member 4
Gene Name SLC2A4
Organism Homo sapiens (Human).
Sequence Length 509
Subcellular Localization Cell membrane
Multi-pass membrane protein. Endomembrane system
Multi-pass membrane protein . Cytoplasm, perinuclear region . Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly r
Protein Description Insulin-regulated facilitative glucose transporter..
Protein Sequence MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTPSLLEQEVKPSTELEYLGPDEND
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of GTR4_HUMAN !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GTR4_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GTR4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GTR4_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
DAXX_HUMANDAXXphysical
11842083
ACTN1_HUMANACTN1physical
16396496
CRNL1_HUMANCRNKL1physical
16396496
ACTN4_HUMANACTN4physical
16396496
ARF5_HUMANARF5physical
16396496
ARF3_HUMANARF3physical
16396496
BASI_HUMANBSGphysical
16396496
G3P_HUMANGAPDHphysical
16396496
DLDH_HUMANDLDphysical
16396496
PDIA6_HUMANPDIA6physical
16396496
SERPH_HUMANSERPINH1physical
16396496
P3H1_HUMANP3H1physical
16396496
SC65_HUMANP3H4physical
16396496
FKB10_HUMANFKBP10physical
16396496
SDF2L_HUMANSDF2L1physical
16396496
KLH41_HUMANKLHL41physical
16396496
RAB7A_HUMANRAB7Aphysical
16396496
NSF_HUMANNSFphysical
16396496
KAP0_HUMANPRKAR1Aphysical
16396496
HXK2_HUMANHK2physical
16396496
ACOX1_HUMANACOX1physical
16396496
IDHC_HUMANIDH1physical
16396496
UBE2N_HUMANUBE2Nphysical
16396496
CATD_HUMANCTSDphysical
16396496
PSMD7_HUMANPSMD7physical
16396496
HS90A_HUMANHSP90AA1physical
16396496
ESYT2_HUMANESYT2physical
16396496
STRN3_HUMANSTRN3physical
16396496
MVP_HUMANMVPphysical
16396496
FACR1_HUMANFAR1physical
16396496
GNL3L_HUMANGNL3Lphysical
16396496
ARFP1_HUMANARFIP1physical
16396496
DJC12_HUMANDNAJC12physical
26186194
WDR73_HUMANWDR73physical
26186194
SMAP2_HUMANSMAP2physical
26186194
AP1M1_HUMANAP1M1physical
19558319
SMAP2_HUMANSMAP2physical
28514442
DJC12_HUMANDNAJC12physical
28514442

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
125853Diabetes mellitus, non-insulin-dependent (NIDDM)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GTR4_HUMAN

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Related Literatures of Post-Translational Modification

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