ERH_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ERH_MOUSE
• UniProt AC: P84089
• Protein Name: Enhancer of rudimentary homolog
• Gene Name: Erh
• Organism: Mus musculus (Mouse).
• Sequence Length: 104
• Protein Description: May have a role in the cell cycle..
• Protein Sequence: MSHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFIDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSHTILLVQ ------CCCEEEEEC	29.36	-
2	Phosphorylation	------MSHTILLVQ ------CCCEEEEEC	29.36	29472430
4	Phosphorylation	----MSHTILLVQPT ----CCCEEEEECCC	13.15	29472430
11	Phosphorylation	TILLVQPTKRPEGRT EEEEECCCCCCCCCC	23.69	-
12	Ubiquitination	ILLVQPTKRPEGRTY EEEECCCCCCCCCCC	73.05	-
12	Malonylation	ILLVQPTKRPEGRTY EEEECCCCCCCCCCC	73.05	26320211
24	Phosphorylation	RTYADYESVNECMEG CCCCCHHHHHHHHHH	24.82	22817900
36	Phosphorylation	MEGVCKMYEEHLKRM HHHHHHHHHHHHHHC	12.03	-
41	Ubiquitination	KMYEEHLKRMNPNSP HHHHHHHHHCCCCCC	52.05	-
82	Phosphorylation	DTQTYQPYNKDWIKE CCCCCCCCCHHHHHH	21.22	17242355
84	Ubiquitination	QTYQPYNKDWIKEKI CCCCCCCHHHHHHHH	48.90	-
84	Acetylation	QTYQPYNKDWIKEKI CCCCCCCHHHHHHHH	48.90	22826441
90	Malonylation	NKDWIKEKIYVLLRR CHHHHHHHHHHHHHH	34.04	26320211
92	Phosphorylation	DWIKEKIYVLLRRQA HHHHHHHHHHHHHHH	8.98	29514104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ERH_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ERH_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ERH_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BCLF1_HUMAN	BCLAF1	physical	20360068
PDIP3_HUMAN	POLDIP3	physical	20360068
FANCE_HUMAN	FANCE	physical	20360068
INF2_HUMAN	INF2	physical	20360068
BCLA3_HUMAN	CXorf23	physical	20360068
ERH_HUMAN	ERH	physical	20360068
MISP_HUMAN	MISP	physical	20360068
CLH1_HUMAN	CLTC	physical	20360068
PPB1_HUMAN	ALPP	physical	20360068
SAM50_HUMAN	SAMM50	physical	20360068
FLOT1_HUMAN	FLOT1	physical	20360068
C1QBP_HUMAN	C1QBP	physical	20360068
RBMX_HUMAN	RBMX	physical	20360068
TR150_HUMAN	THRAP3	physical	20360068
CYTSB_HUMAN	SPECC1	physical	20360068
ANM1_HUMAN	PRMT1	physical	20360068
CHTOP_HUMAN	CHTOP	physical	20360068
MYPT1_HUMAN	PPP1R12A	physical	20360068
THOC4_HUMAN	ALYREF	physical	20360068
DX39A_HUMAN	DDX39A	physical	20360068
F208B_HUMAN	FAM208B	physical	20360068
MIC19_HUMAN	CHCHD3	physical	20360068
DX39B_HUMAN	DDX39B	physical	20360068
PPBN_HUMAN	ALPPL2	physical	20360068
TMOD3_HUMAN	TMOD3	physical	20360068
MIC25_HUMAN	CHCHD6	physical	20360068

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.