BCLA3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BCLA3_HUMAN
• UniProt AC: A2AJT9
• Protein Name: BCLAF1 and THRAP3 family member 3 {ECO:0000312|HGNC:HGNC:27413}
• Gene Name: BCLAF3 {ECO:0000312|HGNC:HGNC:27413}
• Organism: Homo sapiens (Human).
• Sequence Length: 711
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MARSRSRSPRWKHRSLSPVPRNAEHYKQRHSHGHYGCEYRKDPKRPVAWRMDSEKHGQSKPRIPSRGNIYYQSYEHRSPSPNIRNSLENVYMYKPHRGYSPGRGDSNRRAQYMPKYSEGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGKGGKPPQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPEDRDFRKYGHTSKRPKDVERYESREPARNPKWKPEHSLPPYQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDGRTQKYCKEEDRKYSFQKGPLNRELDCFNTGRGRETQDGQVKEPFKPSKKDSIACTYSNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVKVDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGEFAQEIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQSKQAVIYESEQTLIKIIDPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQNSSFSKVKNVHTDGFQKPTHFIKSNFRKCIEKPYMNYTTQRKDIITHKPFEVEGNHRNTRVRPFKSNFRGGRCQPNYKSGLVQKSLYIQAKYQRLRFTGPRGFITHKFRERLMRKKKEYTDVATGI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MARSRSRSPRW ----CCCCCCCCCCC		22468782
6	Phosphorylation	--MARSRSRSPRWKH --CCCCCCCCCCCCC		20068231
8	Phosphorylation	MARSRSRSPRWKHRS CCCCCCCCCCCCCCC		20068231
15	Phosphorylation	SPRWKHRSLSPVPRN CCCCCCCCCCCCCCC		22167270
17	Phosphorylation	RWKHRSLSPVPRNAE CCCCCCCCCCCCCHH		22167270
31	Phosphorylation	EHYKQRHSHGHYGCE HHHHHHHCCCCCCCC		29449344
70	Phosphorylation	IPSRGNIYYQSYEHR CCCCCCEEEECCCCC		28152594
71	Phosphorylation	PSRGNIYYQSYEHRS CCCCCEEEECCCCCC		25219547
73	Phosphorylation	RGNIYYQSYEHRSPS CCCEEEECCCCCCCC		23401153
74	Phosphorylation	GNIYYQSYEHRSPSP CCEEEECCCCCCCCC		17081983
78	Phosphorylation	YQSYEHRSPSPNIRN EECCCCCCCCCCHHH		23401153
80	Phosphorylation	SYEHRSPSPNIRNSL CCCCCCCCCCHHHHH		23401153
94	Acetylation	LENVYMYKPHRGYSP HCCEEEECCCCCCCC		26051181
99	Phosphorylation	MYKPHRGYSPGRGDS EECCCCCCCCCCCCC		24117733
100	Phosphorylation	YKPHRGYSPGRGDSN ECCCCCCCCCCCCCC		27422710
106	Phosphorylation	YSPGRGDSNRRAQYM CCCCCCCCCHHHHHC		27174698
112	Phosphorylation	DSNRRAQYMPKYSEG CCCHHHHHCCCCCCC		27174698
115	Sumoylation	RRAQYMPKYSEGIPY HHHHHCCCCCCCCCC		-
116	Phosphorylation	RAQYMPKYSEGIPYK HHHHCCCCCCCCCCC		29978859
117	Phosphorylation	AQYMPKYSEGIPYKE HHHCCCCCCCCCCCC		29978859
122	Phosphorylation	KYSEGIPYKEHERNS CCCCCCCCCCCCCCC		29978859
129	Phosphorylation	YKEHERNSYPQKVQG CCCCCCCCCCCCCCC		29978859
130	Phosphorylation	KEHERNSYPQKVQGG CCCCCCCCCCCCCCC		29978859
139	Phosphorylation	QKVQGGHSPDDHRVR CCCCCCCCCCCCCCC		16565220
158	Phosphorylation	GGKPPQRSIADSFRF CCCCCCCCHHHHHCC		27499020
162	Phosphorylation	PQRSIADSFRFEGKW CCCCHHHHHCCCCCC		27251275
183	Sumoylation	HQRIQEEKYSQSTRR HHHHHHHHHCHHHCC		-
184	Phosphorylation	QRIQEEKYSQSTRRG HHHHHHHHCHHHCCC		28270605
185	Phosphorylation	RIQEEKYSQSTRRGS HHHHHHHCHHHCCCC		28270605
187	Phosphorylation	QEEKYSQSTRRGSED HHHHHCHHHCCCCCC		28270605
188	Phosphorylation	EEKYSQSTRRGSEDF HHHHCHHHCCCCCCH		28270605
192	Phosphorylation	SQSTRRGSEDFETRS CHHHCCCCCCHHHHH		23401153
197	Phosphorylation	RGSEDFETRSSFQKR CCCCCHHHHHHHHHH		28102081
243	Phosphorylation	PKWKPEHSLPPYQED CCCCCCCCCCCCCCC		24719451
311	Phosphorylation	CKEEDRKYSFQKGPL HCHHHHCCCCCCCCC		23312004
312	Phosphorylation	KEEDRKYSFQKGPLN CHHHHCCCCCCCCCC		22798277
383	Phosphorylation	EGDCRKESNSSSNQL HCCCCCCCCCCCCCC		29978859
385	Phosphorylation	DCRKESNSSSNQLDK CCCCCCCCCCCCCCH		29978859
386	Phosphorylation	CRKESNSSSNQLDKS CCCCCCCCCCCCCHH		29978859
387	Phosphorylation	RKESNSSSNQLDKSQ CCCCCCCCCCCCHHH		29978859
400	Sumoylation	SQKLPDVKPSPINLR HHCCCCCCCCCCCCC		28112733
400	Sumoylation	SQKLPDVKPSPINLR HHCCCCCCCCCCCCC		-
402	Phosphorylation	KLPDVKPSPINLRKK CCCCCCCCCCCCCCC		25159151
429	Phosphorylation	DTFRVASSYSTERQM EHHHHCCCCCCCCCC		28102081
431	Phosphorylation	FRVASSYSTERQMSH HHHCCCCCCCCCCCC		28102081
432	Phosphorylation	RVASSYSTERQMSHD HHCCCCCCCCCCCCC		28102081
486	Phosphorylation	IHQVKANYFPSPGIT HHHHHCCCCCCCCEE		26270265
489	Phosphorylation	VKANYFPSPGITLHE HHCCCCCCCCEEHHH		25159151
493	Phosphorylation	YFPSPGITLHERFST CCCCCCEEHHHHHHC		26270265
499	Phosphorylation	ITLHERFSTMQDIHK EEHHHHHHCHHHHHH		23612710
578	Phosphorylation	EHIFHIASAAERDDQ CCHHHHHHHHHCCCC		28555341
588	Phosphorylation	ERDDQNSSFSKVKNV HCCCCCCCCHHCEEC		24719451
627	Acetylation	MNYTTQRKDIITHKP CCCCCCCCCCCCCCC		19823499
651	Phosphorylation	TRVRPFKSNFRGGRC CCEECCCCCCCCCCC		26074081
662	Phosphorylation	GGRCQPNYKSGLVQK CCCCCCCCCCCCCCH		26074081
664	Phosphorylation	RCQPNYKSGLVQKSL CCCCCCCCCCCCHHH		26074081
683	Phosphorylation	KYQRLRFTGPRGFIT HHHHHHCCCCCCHHH		24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BCLA3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BCLA3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BCLA3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of BCLA3_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.