dbPTM

CONS_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CONS_ARATH
UniProt AC	Q39057
Protein Name	Zinc finger protein CONSTANS {ECO:0000303\|PubMed:7697715}
Gene Name	CO {ECO:0000303\|PubMed:7697715}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	373
Subcellular Localization	Nucleus .
Protein Description	Transcription factor that acts in the long day flowering pathway and may mediate between the circadian clock and the control of flowering. Plays a role in the regulation of flowering time by acting on 'SUPPRESSOR OF OVEREXPRESSION OF CO1', 'TERMINAL FLOWER 1' and 'FLOWERING LOCUS T'. Also regulates P5CS2 and ACS10 (involved in proline and ethylene biosynthesis, respectively). Regulates the expression of NAKR1 by binding to the 5'-TGTG(N2-3)ATG-3' motif. [PubMed: 27255839]
Protein Sequence	MLKQESNDIGSGENNRARPCDTCRSNACTVYCHADSAYLCMSCDAQVHSANRVASRHKRVRVCESCERAPAAFLCEADDASLCTACDSEVHSANPLARRHQRVPILPISGNSFSSMTTTHHQSEKTMTDPEKRLVVDQEEGEEGDKDAKEVASWLFPNSDKNNNNQNNGLLFSDEYLNLVDYNSSMDYKFTGEYSQHQQNCSVPQTSYGGDRVVPLKLEESRGHQCHNQQNFQFNIKYGSSGTHYNDNGSINHNAYISSMETGVVPESTACVTTASHPRTPKGTVEQQPDPASQMITVTQLSPMDREARVLRYREKRKTRKFEKTIRYASRKAYAEIRPRVNGRFAKREIEAEEQGFNTMLMYNTGYGIVPSF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of CONS_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
-	K	Ubiquitination	E3 ubiquitin ligase	COP1	P43254	PMID:22199232

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CONS_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CONS_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NFYC1_ARATH	NF-YC1	physical	17138697
NFYC2_ARATH	NF-YC2	physical	17138697
NFYC9_ARATH	NF-YC9	physical	17138697
NFYB1_ARATH	NF-YB1	physical	17138697
NFYB2_ARATH	NF-YB2	physical	17138697
GIGAN_ARATH	GI	genetic	16006578
SPY_ARATH	SPY	genetic	15155885
ASHH2_ARATH	EFS	genetic	10518493
ADO2_ARATH	LKP2	physical	15937324
DI197_ARATH	HRB1	genetic	17916114
ELF3_ARATH	ELF3	genetic	16258016
COP1_ARATH	COP1	physical	18296627
AS1_ARATH	AS1	physical	21950734
ADO3_ARATH	FKF1	physical	22628657
COP1_ARATH	COP1	physical	18388858
HOS1_ARATH	HOS1	physical	23135282
NFYC3_ARATH	NF-YC3	physical	25105952
NFYC9_ARATH	NF-YC9	physical	25105952
NFYC1_ARATH	NF-YC1	physical	25105952
NFYB2_ARATH	NF-YB2	physical	25105952
NFYA2_ARATH	NF-YA2	physical	25105952
GIGAN_ARATH	GI	physical	25422419
ADO3_ARATH	FKF1	physical	25422419
ADO1_ARATH	ZTL	physical	25422419
BBX19_ARATH	AT4G38960	physical	25228341
BOI_ARATH	RING	physical	26298008
BRG2_ARATH	AT1G79110	physical	26298008
BRG3_ARATH	AT3G12920	physical	26298008
DET1_ARATH	DET1	genetic	25962685
HOS1_ARATH	HOS1	physical	26373454
PHYB_ARATH	PHYB	physical	26373454

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CONS_ARATH

Related Literatures of Post-Translational Modification