| UniProt ID | DET1_ARATH | |
|---|---|---|
| UniProt AC | P48732 | |
| Protein Name | Light-mediated development protein DET1 | |
| Gene Name | DET1 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 543 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness by participating in the CDD complex, a complex probably required to regulate the activity of ubiquitin conjugating enzymes (E2s). Involved in repression of deetiolation in the developing seedling. Repression of photomorphogenesis is probably mediated by ubiquitination and subsequent degradation of photomorphogenesis-promoting factors such as HY5, HYH and LAF1. Involved in the repression of blue light responsive promoter in chloroplasts. May be required to stabilize the CDD complex. Its association with histone tail suggests a role in remodeling of chromatin.. | |
| Protein Sequence | MFTSGNVTARVFERQIRTPPPGASVNRARHFYENLVPSYTLYDVESPDHCFRKFTEDGLFLISFSRNHQELIVYRPSWLTYSTTDDSTTTLPPLPRRASKFDSFFTQLYSVNLASSNELICKDFFLYHQTRRFGLFATSTAQIHDSSSPSNDAVPGVPSIDKITFVLLRLDDGVVLDERVFLHDFVNLAHNMGVFLYDDLLAILSLRYQRIHLLQIRDSGHLVDARAIGYFCREDDELFLNSSSQAMMSQDKSKQQSLSGSKEDDTGENGLRHSLSQPSGSNSFLSGVKQRLLSFIFREIWNEESDNVMRVQSLKKKFYFHFQDYVDLIIWKVQFLDRQHLLIKFGSVDGGVTRSADHHPAFFAVYNMETTDIVAFYQNSAEDLYQLFEQFSDHFTVSSSTPFMNFVTSHSNNVYALEQLKYTKNKSNSFSQFVKKMLLSLPFSCQSQSPSPYFDQSLFRFDEKLISAADRHRQSSDNPIKFISRRQPQTLKFKIKPGPECGTADGRSKKICSFLFHPHLPLAISIQQTLFMPPSVVNIHFRR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 484 | Phosphorylation | DNPIKFISRRQPQTL CCCCEEEECCCCCEE | 25.25 | 24894044 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of DET1_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DET1_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DET1_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| HY5_ARATH | HY5 | genetic | 14563928 | |
| CUL4_ARATH | CUL4 | physical | 20061554 | |
| DDB1A_ARATH | DDB1A | physical | 20061554 | |
| COP1_ARATH | COP1 | physical | 20061554 | |
| CCA1_ARATH | CCA1 | physical | 21884973 | |
| LHY_ARATH | LHY | physical | 21884973 | |
| DDB1A_ARATH | DDB1A | physical | 12225661 | |
| PIF1_ARATH | PIL5 | physical | 25248553 | |
| PIF3_ARATH | PIF3 | physical | 25248553 | |
| PIF4_ARATH | PIF4 | physical | 25248553 | |
| PIF5_ARATH | PIL6 | physical | 25248553 | |
| PIF6_ARATH | PIL2 | physical | 25248553 | |
| PIF7_ARATH | PIF7 | physical | 25248553 | |
| DDB1A_ARATH | DDB1A | genetic | 25575996 | |
| COP1_ARATH | COP1 | genetic | 25575996 | |
| COP10_ARATH | FUS9 | physical | 25962685 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
