| UniProt ID | LHY_ARATH | |
|---|---|---|
| UniProt AC | Q6R0H1 | |
| Protein Name | Protein LHY {ECO:0000303|PubMed:9657154} | |
| Gene Name | LHY {ECO:0000303|PubMed:9657154} | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 645 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Transcription factor involved in the circadian clock. Binds to the promoter region of APRR1/TOC1 and TCP21/CHE to repress their transcription. Represses both CCA1 and itself.. | |
| Protein Sequence | MDTNTSGEELLAKARKPYTITKQRERWTEDEHERFLEALRLYGRAWQRIEEHIGTKTAVQIRSHAQKFFTKLEKEAEVKGIPVCQALDIEIPPPRPKRKPNTPYPRKPGNNGTSSSQVSSAKDAKLVSSASSSQLNQAFLDLEKMPFSEKTSTGKENQDENCSGVSTVNKYPLPTKQVSGDIETSKTSTVDNAVQDVPKKNKDKDGNDGTTVHSMQNYPWHFHADIVNGNIAKCPQNHPSGMVSQDFMFHPMREETHGHANLQATTASATTTASHQAFPACHSQDDYRSFLQISSTFSNLIMSTLLQNPAAHAAATFAASVWPYASVGNSGDSSTPMSSSPPSITAIAAATVAAATAWWASHGLLPVCAPAPITCVPFSTVAVPTPAMTEMDTVENTQPFEKQNTALQDQNLASKSPASSSDDSDETGVTKLNADSKTNDDKIEEVVVTAAVHDSNTAQKKNLVDRSSCGSNTPSGSDAETDALDKMEKDKEDVKETDENQPDVIELNNRKIKMRDNNSNNNATTDSWKEVSEEGRIAFQALFARERLPQSFSPPQVAENVNRKQSDTSMPLAPNFKSQDSCAADQEGVVMIGVGTCKSLKTRQTGFKPYKRCSMEVKESQVGNINNQSDEKVCKRLRLEGEAST | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MDTNTSGEELLA ---CCCCCCHHHHHH | 39.95 | 25561503 | |
| 6 | Phosphorylation | --MDTNTSGEELLAK --CCCCCCHHHHHHH | 46.40 | 25561503 | |
| 128 | Phosphorylation | AKDAKLVSSASSSQL HHHHHHHHCCCHHHH | 30.53 | 27029354 | |
| 129 | Phosphorylation | KDAKLVSSASSSQLN HHHHHHHCCCHHHHH | 25.37 | 27029354 | |
| 131 | Phosphorylation | AKLVSSASSSQLNQA HHHHHCCCHHHHHHH | 32.25 | 23111157 | |
| 132 | Phosphorylation | KLVSSASSSQLNQAF HHHHCCCHHHHHHHH | 23.09 | 23111157 | |
| 133 | Phosphorylation | LVSSASSSQLNQAFL HHHCCCHHHHHHHHH | 35.87 | 27029354 | |
| 644 | Phosphorylation | LRLEGEAST------ HHHCCCCCC------ | 30.28 | 25561503 | |
| 645 | Phosphorylation | RLEGEAST------- HHCCCCCC------- | 50.07 | 29654922 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of LHY_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of LHY_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of LHY_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CCA1_ARATH | CCA1 | genetic | 17483414 | |
| APRR1_ARATH | TOC1 | genetic | 17483414 | |
| CCA1_ARATH | CCA1 | genetic | 12015970 | |
| CSK2D_ARATH | CKB3 | physical | 10535927 | |
| GIGAN_ARATH | GI | genetic | 16006578 | |
| CCA1_ARATH | CCA1 | genetic | 17540692 | |
| APRR1_ARATH | TOC1 | genetic | 17540692 | |
| APRR1_ARATH | TOC1 | genetic | 17519251 | |
| CCA1_ARATH | CCA1 | genetic | 17504813 | |
| TIC_ARATH | TIC | genetic | 17496120 | |
| TCP2_ARATH | TCP2 | physical | 21183706 | |
| CCA1_ARATH | CCA1 | physical | 19218364 | |
| LHY_ARATH | LHY | physical | 19218364 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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