ZN124_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN124_HUMAN
• UniProt AC: Q15973
• Protein Name: Zinc finger protein 124
• Gene Name: ZNF124
• Organism: Homo sapiens (Human).
• Sequence Length: 351
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MSGHPGSWEMNSVAFEDVAVNFTQEEWALLDPSQKNLYRDVMQETFRNLASIGNKGEDQSIEDQYKNSSRNLRHIISHSGNNPYGCEECGKKPCTCKQCQKTSLSVTRVHRDTVMHTGNGHYGCTICEKVFNIPSSFQIHQRNHTGEKPYECMECGKALGFSRSLNRHKRIHTGEKRYECKQCGKAFSRSSHLRDHERTHTGEKPYECKHCGKAFRYSNCLHYHERTHTGEKPYVCMECGKAFSCLSSLQGHIKAHAGEEPYPCKQCGKAFRYASSLQKHEKTHIAQKPYVCNNCGKGFRCSSSLRDHERTHTGEKPYECQKCGKAFSRASTLWKHKKTHTGEKPYKCKKM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSGHPGSWE ------CCCCCCCCC	45.89	23401153
12	Phosphorylation	PGSWEMNSVAFEDVA CCCCCCCCCEEEEEE	17.32	22210691
23	Phosphorylation	EDVAVNFTQEEWALL EEEEEECCHHHHHCC	29.84	22210691
33	Phosphorylation	EWALLDPSQKNLYRD HHHCCCHHHHHHHHH	54.15	22210691
38	Phosphorylation	DPSQKNLYRDVMQET CHHHHHHHHHHHHHH	17.73	-
55	Ubiquitination	NLASIGNKGEDQSIE HHHHCCCCCCCCCHH	59.47	-
79	Phosphorylation	LRHIISHSGNNPYGC HHHHHHCCCCCCCCC	36.10	28555341
102	Phosphorylation	TCKQCQKTSLSVTRV CCCCCCCCCCEEEEE	14.71	24275569
103	Phosphorylation	CKQCQKTSLSVTRVH CCCCCCCCCEEEEEE	26.19	29743597
105	Phosphorylation	QCQKTSLSVTRVHRD CCCCCCCEEEEEEEC	22.62	24702127
107	Phosphorylation	QKTSLSVTRVHRDTV CCCCCEEEEEEECCE	24.49	29743597
199	Phosphorylation	HLRDHERTHTGEKPY HCCCCCCCCCCCCCC	22.32	29396449
201	Phosphorylation	RDHERTHTGEKPYEC CCCCCCCCCCCCCCC	46.56	29496963
217	Phosphorylation	HCGKAFRYSNCLHYH CCCCEEECCCCCCEE	9.59	28555341
218	Phosphorylation	CGKAFRYSNCLHYHE CCCEEECCCCCCEEE	19.46	28555341
227	Phosphorylation	CLHYHERTHTGEKPY CCCEEECCCCCCCCE	22.32	-
229	Phosphorylation	HYHERTHTGEKPYVC CEEECCCCCCCCEEE	46.56	-
234	Phosphorylation	THTGEKPYVCMECGK CCCCCCCEEEECCCC	19.83	18083107
262	Phosphorylation	AHAGEEPYPCKQCGK HCCCCCCCCCCHHHH	25.25	18083107
288	Acetylation	EKTHIAQKPYVCNNC CCCCCCCCCEECCCC	29.33	30593567
302	Phosphorylation	CGKGFRCSSSLRDHE CCCCCCCCHHHCCCC	20.78	28555341
311	Phosphorylation	SLRDHERTHTGEKPY HHCCCCCCCCCCCCC	22.32	-
313	Phosphorylation	RDHERTHTGEKPYEC CCCCCCCCCCCCCCH	46.56	-
339	Phosphorylation	TLWKHKKTHTGEKPY HHHHCCCCCCCCCCC	29.49	28348404
341	Phosphorylation	WKHKKTHTGEKPYKC HHCCCCCCCCCCCCC	52.87	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN124_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN124_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN124_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CCDB1_HUMAN	CCNDBP1	physical	25416956
TSG10_HUMAN	TSGA10	physical	25416956
KRA42_HUMAN	KRTAP4-2	physical	25416956
SYCE1_HUMAN	SYCE1	physical	25416956
ADIP_HUMAN	SSX2IP	physical	25416956
FSD2_HUMAN	FSD2	physical	25416956
K1C40_HUMAN	KRT40	physical	25416956
KR107_HUMAN	KRTAP10-7	physical	25416956
KR109_HUMAN	KRTAP10-9	physical	25416956
KR101_HUMAN	KRTAP10-1	physical	25416956
KR108_HUMAN	KRTAP10-8	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956
NT2NL_HUMAN	NOTCH2NL	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.