Y5129_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: Y5129_ARATH
• UniProt AC: C0LGT1
• Protein Name: Probable LRR receptor-like serine/threonine-protein kinase At5g10290
• Gene Name: At5g10290
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 613
• Subcellular Localization: Cell membrane; Single-pass type I membrane protein.
• Protein Sequence: MRMFSLQKMAMAFTLLFFACLCSFVSPDAQGDALFALRISLRALPNQLSDWNQNQVNPCTWSQVICDDKNFVTSLTLSDMNFSGTLSSRVGILENLKTLTLKGNGITGEIPEDFGNLTSLTSLDLEDNQLTGRIPSTIGNLKKLQFLTLSRNKLNGTIPESLTGLPNLLNLLLDSNSLSGQIPQSLFEIPKYNFTSNNLNCGGRQPHPCVSAVAHSGDSSKPKTGIIAGVVAGVTVVLFGILLFLFCKDRHKGYRRDVFVDVAGEVDRRIAFGQLKRFAWRELQLATDNFSEKNVLGQGGFGKVYKGVLPDNTKVAVKRLTDFESPGGDAAFQREVEMISVAVHRNLLRLIGFCTTQTERLLVYPFMQNLSLAHRLREIKAGDPVLDWETRKRIALGAARGFEYLHEHCNPKIIHRDVKAANVLLDEDFEAVVGDFGLAKLVDVRRTNVTTQVRGTMGHIAPEYLSTGKSSERTDVFGYGIMLLELVTGQRAIDFSRLEEEDDVLLLDHVKKLEREKRLGAIVDKNLDGEYIKEEVEMMIQVALLCTQGSPEDRPVMSEVVRMLEGEGLAERWEEWQNVEVTRRHEFERLQRRFDWGEDSMHNQDAIELSGGR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
81	N-linked_Glycosylation	SLTLSDMNFSGTLSS EEEECCCCCCCCHHH	32.68	-
116	N-linked_Glycosylation	EIPEDFGNLTSLTSL CCCCCCCCCCCCEEE	39.89	-
155	N-linked_Glycosylation	TLSRNKLNGTIPESL EECCCCCCCCCCHHH	47.36	-
193	N-linked_Glycosylation	LFEIPKYNFTSNNLN HHCCCCCCCCCCCCC	39.59	-
287	Phosphorylation	WRELQLATDNFSEKN HHHHHHHCCCCCCCC	39.82	-
313	Phosphorylation	KGVLPDNTKVAVKRL CCCCCCCCEEEEEEH	33.99	-
325	Phosphorylation	KRLTDFESPGGDAAF EEHHCCCCCCCCHHH	28.92	17317660
371	Phosphorylation	YPFMQNLSLAHRLRE HHHHHCHHHHHHHHH	30.93	-
390	Phosphorylation	DPVLDWETRKRIALG CCCCCHHHHHHHHHH	36.92	-
450	Phosphorylation	DVRRTNVTTQVRGTM EEECCCCCEEEECCC	17.37	-
451	Phosphorylation	VRRTNVTTQVRGTMG EECCCCCEEEECCCC	22.30	-
456	Phosphorylation	VTTQVRGTMGHIAPE CCEEEECCCCCCCHH	14.93	-
464	Phosphorylation	MGHIAPEYLSTGKSS CCCCCHHHHHCCCCC	12.61	-
466	Phosphorylation	HIAPEYLSTGKSSER CCCHHHHHCCCCCCC	33.92	-
467	Phosphorylation	IAPEYLSTGKSSERT CCHHHHHCCCCCCCC	46.14	-
471	Phosphorylation	YLSTGKSSERTDVFG HHHCCCCCCCCCCCH	34.29	-
547	Phosphorylation	IQVALLCTQGSPEDR HHHHHHHCCCCCCCC	35.61	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of Y5129_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of Y5129_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of Y5129_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
Y2289_ARATH	AT2G28960	physical	21423366
LUT1_ARATH	LUT1	physical	24833385
HHP2_ARATH	HHP2	physical	24833385
HHP4_ARATH	HHP4	physical	24833385
UBC34_ARATH	UBC34	physical	24833385
UBC32_ARATH	UBC32	physical	24833385
ACBP6_ARATH	ACBP6	physical	24833385
TRXH5_ARATH	TRX5	physical	24833385
CALX2_ARATH	AT5G07340	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
SBP3_ARATH	MAPR2	physical	24833385
MSBP2_ARATH	MAPR3	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
SPCS1_ARATH	AT2G22425	physical	24833385
RAH1C_ARATH	RABH1c	physical	24833385
RAA2C_ARATH	RABA2c	physical	24833385
PAM74_ARATH	AT5G59650	physical	24833385
VA723_ARATH	VAMP723	physical	24833385
BET12_ARATH	ATBET12	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomics of early elicitor signaling inArabidopsis.";
Benschop J.J., Mohammed S., O'Flaherty M., Heck A.J.R., Slijper M.,Menke F.L.H.;
Mol. Cell. Proteomics 6:1198-1214(2007).
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS],PHOSPHORYLATION AT SER-325, AND SUBCELLULAR LOCATION.
PubMed: 17317660