MSBP2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MSBP2_ARATH
• UniProt AC: Q9M2Z4
• Protein Name: Membrane steroid-binding protein 2
• Gene Name: MSBP2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 233
• Subcellular Localization: Cell membrane.
• Protein Sequence: MVQQIWETLKETITAYTGLSPAAFFTVLALAFAVYQVVSGFFVSPEVHRPRSLEVQPQSEPLPPPVQLGEITEEELKLYDGSDSKKPLLMAIKGQIYDVSQSRMFYGPGGPYALFAGKDASRALAKMSFEDQDLTGDISGLGAFELEALQDWEYKFMSKYVKVGTIQKKDGEGKESSEPSEAKTASAEGLSTNTGEEASAITHDETSRSTGEKIAETTEKKDVATDDDDAAKE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
118	Ubiquitination	PYALFAGKDASRALA CCEEEECHHHHHHHH	46.84	-
162	Ubiquitination	KFMSKYVKVGTIQKK HHHHHEEEEEEEEEE	31.68	-
174	Ubiquitination	QKKDGEGKESSEPSE EEECCCCCCCCCCCH	50.55	-
176	Phosphorylation	KDGEGKESSEPSEAK ECCCCCCCCCCCHHH	43.41	25561503
177	Phosphorylation	DGEGKESSEPSEAKT CCCCCCCCCCCHHHC	55.40	30407730
180	Phosphorylation	GKESSEPSEAKTASA CCCCCCCCHHHCCCC	46.24	25561503
183	Ubiquitination	SSEPSEAKTASAEGL CCCCCHHHCCCCCCC	40.34	-
184	Phosphorylation	SEPSEAKTASAEGLS CCCCHHHCCCCCCCC	32.65	30407730
186	Phosphorylation	PSEAKTASAEGLSTN CCHHHCCCCCCCCCC	31.89	30407730
191	Phosphorylation	TASAEGLSTNTGEEA CCCCCCCCCCCCCHH	30.39	30407730
192	Phosphorylation	ASAEGLSTNTGEEAS CCCCCCCCCCCCHHH	41.67	19376835
194	Phosphorylation	AEGLSTNTGEEASAI CCCCCCCCCCHHHHC	46.16	30407730
199	Phosphorylation	TNTGEEASAITHDET CCCCCHHHHCCCCCC	24.39	19376835
202	Phosphorylation	GEEASAITHDETSRS CCHHHHCCCCCCCCH	24.00	30407730
206	Phosphorylation	SAITHDETSRSTGEK HHCCCCCCCCHHCCH	35.18	30407730
207	Phosphorylation	AITHDETSRSTGEKI HCCCCCCCCHHCCHH	23.37	19376835
213	Ubiquitination	TSRSTGEKIAETTEK CCCHHCCHHHHHHCC	48.86	-
225	Phosphorylation	TEKKDVATDDDDAAK HCCCCCCCCCCHHHH	39.55	19880383
232	Ubiquitination	TDDDDAAKE------ CCCCHHHHC------	66.72	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MSBP2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MSBP2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MSBP2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBQ10_ARATH	UBQ10	physical	22513011

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-225, AND MASSSPECTROMETRY.
PubMed: 19376835

"Site-specific phosphorylation profiling of Arabidopsis proteins bymass spectrometry and peptide chip analysis.";
de la Fuente van Bentem S., Anrather D., Dohnal I., Roitinger E.,Csaszar E., Joore J., Buijnink J., Carreri A., Forzani C.,Lorkovic Z.J., Barta A., Lecourieux D., Verhounig A., Jonak C.,Hirt H.;
J. Proteome Res. 7:2458-2470(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-225, AND MASSSPECTROMETRY.
PubMed: 18433157