VBA3_YEAST - dbPTM
VBA3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID VBA3_YEAST
UniProt AC P25594
Protein Name Vacuolar basic amino acid transporter 3
Gene Name VBA3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 458
Subcellular Localization Vacuole membrane
Multi-pass membrane protein.
Protein Description Transporter required for vacuolar uptake of histidine and lysine..
Protein Sequence MNMLIVGRVVASVGGSGLQTLCFVIGCTMVGERSRPLVISILSCAFAVAAIVGPIIGGAFTTHVTWRWCFYINLPIGGLAIIMFLLTYKAENKGILQQIKDAIGTISSFTFSKFRHQVNFKRLMNGIIFKFDFFGFALCSAGLVLFLLGLTFGGNKYSWNSGQVIAYLVLGVLLFIFSLVYDFFLFDKFNPEPDNISYRPLLLRRLVAKPAIIIINMVTFLLCTGYNGQMIYSVQFFQLIFASSAWKAGLHLIPIVITNVIAAIASGVITKKLGLVKPLLIFGGVLGVIGAGLMTLMTNTSTKSTQIGVLLLPGFSLGFALQASLMSAQLQITKDRPEAAMDFIEVTAFNTFMKSLGTTLGGVLSTTVFSASFHNKVSRAHLEPYEGKTVDDMILYRLQNYDGSHSTIGNILSDSIKNVFWMDLGFYALGFLFCSFSSNKKLIIPKKDETPEDNLEDK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
195N-linked_GlycosylationKFNPEPDNISYRPLL
CCCCCCCCCCCHHHH
35.50-
359PhosphorylationFMKSLGTTLGGVLST
HHHHHCCCHHHHHHC
22.9328889911
365PhosphorylationTTLGGVLSTTVFSAS
CCHHHHHHCEEEHHH
21.4528889911
370PhosphorylationVLSTTVFSASFHNKV
HHHCEEEHHHHCCCC
20.7628889911
372PhosphorylationSTTVFSASFHNKVSR
HCEEEHHHHCCCCCH
26.3228889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of VBA3_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of VBA3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of VBA3_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
VBA2_YEASTVBA2genetic
15572352
VBA1_YEASTVBA1genetic
15572352
PAA1_YEASTPAA1genetic
20093466
SAS4_YEASTSAS4genetic
20093466
DHOM_YEASTHOM6genetic
20093466
MSN1_YEASTMSN1genetic
20093466
RTG1_YEASTRTG1genetic
20093466
TCB1_YEASTTCB1genetic
20093466
MCA1_YEASTMCA1genetic
20093466
ERS1_YEASTERS1physical
16093310
BET1_YEASTBET1physical
16093310
PAA1_YEASTPAA1genetic
27708008
LSM6_YEASTLSM6genetic
27708008
GTR2_YEASTGTR2genetic
27708008
ATP23_YEASTATP23genetic
27708008
MCA1_YEASTMCA1genetic
27708008
SYH1_YEASTSYH1genetic
27708008
BEM4_YEASTBEM4genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of VBA3_YEAST

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Related Literatures of Post-Translational Modification

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