| UniProt ID | REV3L_HUMAN | |
|---|---|---|
| UniProt AC | O60673 | |
| Protein Name | DNA polymerase zeta catalytic subunit | |
| Gene Name | REV3L | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 3130 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function.. | |
| Protein Sequence | MFSVRIVTADYYMASPLQGLDTCQSPLTQAPVKKVPVVRVFGATPAGQKTCLHLHGIFPYLYVPYDGYGQQPESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKERHFMKIYLYNPTMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKSNTLHATGSCKNHLSGNSLADTLFRWEQDEIPSSLILEGVEPQSTCELEVDAVAADILNRLDIEAQIGGNPGLQAIWEDEKQRRRNRNETSQMSQPESQDHRFVPATESEKKFQKRLQEILKQNDFSVTLSGSVDYSDGSQEFSAELTLHSEVLSPEMLQCTPANMVEVHKDKESSKGHTRHKVEEALINEEAILNLMENSQTFQPLTQRLSESPVFMDSSPDEALVHLLAGLESDGYRGERNRMPSPCRSFGNNKYPQNSDDEENEPQIEKEEMELSLVMSQRWDSNIEEHCAKKRSLCRNTHRSSTEDDDSSSGEEMEWSDNSLLLASLSIPQLDGTADENSDNPLNNENSRTHSSVIATSKLSVKPSIFHKDAATLEPSSSAKITFQCKHTSALSSHVLNKEDLIEDLSQTNKNTEKGLDNSVTSFTNESTYSMKYPGSLSSTVHSENSHKENSKKEILPVSSCESSIFDYEEDIPSVTRQVPSRKYTNIRKIEKDSPFIHMHRHPNENTLGKNSFNFSDLNHSKNKVSSEGNEKGNSTALSSLFPSSFTENCELLSCSGENRTMVHSLNSTADESGLNKLKIRYEEFQEHKTEKPSLSQQAAHYMFFPSVVLSNCLTRPQKLSPVTYKLQPGNKPSRLKLNKRKLAGHQETSTKSSETGSTKDNFIQNNPCNSNPEKDNALASDLTKTTRGAFENKTPTDGFIDCHFGDGTLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKISLPHPMEIGESLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKKKTGKQQRTNNENIKRTLSFRKKRSHAILSPPSPSYNAETEDCDLNYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEIMAAAEKEAMLFKGPNVYKKTVNSRIGKTSRARAQIKKSKAKLANPSIVTKKRNKRNQTNKLVDDGKKKPRAKQKTNEKGTSRKHTTLKDEKIKSQSGAEVKFVLKHQNVSEFASSSGGSQLLFKQKDMPLMGSAVDHPLSASLPTGINAQQKLSGCFSSFLESKKSVDLQTFPSSRDDLHPSVVCNSIGPGVSKINVQRPHNQSAMFTLKESTLIQKNIFDLSNHLSQVAQNTQISSGMSSKIEDNANNIQRNYLSSIGKLSEYRNSLESKLDQAYTPNFLHCKDSQQQIVCIAEQSKHSETCSPGNTASEESQMPNNCFVTSLRSPIKQIAWEQKQRGFILDMSNFKPERVKPRSLSEAISQTKALSQCKNRNVSTPSAFGEGQSGLAVLKELLQKRQQKAQNANTTQDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPRKPRTPRSTKQKEKIPKLLKVDSLNLQNSSQLDNSVSDDSPIFFSDPGFESCYSLEDSLSPEHNYNFDINTIGQTGFCSFYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIEKNEFLSHDNQKCDEDKHHTTDSASWIRSGTLSPEIFEKSTIDSNENRRHNQWKNSFHPLTTRSNSIMDSFCVQQAEDCLSEKSRLNRSSVSKEVFLSLPQPNNSDWIQGHTRKEMGQSLDSANTSFTAILSSPDGELVDVACEDLELYVSRNNDMLTPTPDSSPRSTSSPSQSKNGSFTPRTANILKPLMSPPSREEIMATLLDHDLSETIYQEPFCSNPSDVPEKPREIGGRLLMVETRLANDLAEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRSGQGVVNKGSSNSPKMVEDKKIVIMPCKCAPSRQLVQVWLQAKEEYERSKKLPKTKPTGVVKSAENFSSSVNPDDKPVVPPKMDVSPCILPTTAHTKEDVDNSQIALQAPTTGCSQTASESQMLPPVASASDPEKDEDDDDNYYISYSSPDSPVIPPWQQPISPDSKALNGDDRPSSPVEELPSLAFENFLKPIKDGIQKSPCSEPQEPLVISPINTRARTGKCESLCFHSTPIIQRKLLERLPEAPGLSPLSTEPKTQKLSNKKGSNTDTLRRVLLTQAKNQFAAVNTPQKETSQIDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHARTRRDLEPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVFSQDIRYQTPLLIRSGITGLEVTYAADEKALFHEIANIIKRYDPDILLGYEIQMHSWGYLLQRAAALSIDLCRMISRVPDDKIENRFAAERDEYGSYTMSEINIVGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVTPSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPDLLYQVRHDITVSPNGVAFVKPSVRKGVLPRMLEEILKTRFMVKQSMKAYKQDRALSRMLDARQLGLKLIANVTFGYTSANFSGRMPCIEVGDSIVHKARETLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLLEGKASIQDFIFAKEYRGSFSYKPGACVPALELTRKMLTYDRRSEPQVGERVPYVIIYGTPGVPLIQLVRRPVEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSWYHELPRIHKATSSSRSEPEGRKGTISQYFTTLHCPVCDDLTQHGICSKCRSQPQHVAVILNQEIRELERQQEQLVKICKNCTGCFDRHIPCVSLNCPVLFKLSRVNRELSKAPYLRQLLDQF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 68 | Phosphorylation | LYVPYDGYGQQPESY EECCCCCCCCCCHHH | - | ||
| 105 | Phosphorylation | AQHVFKVSLVSGMPF HHHEEEEEEECCCCC | 27732954 | ||
| 108 | Phosphorylation | VFKVSLVSGMPFYGY EEEEEEECCCCCCCC | 27732954 | ||
| 113 | Phosphorylation | LVSGMPFYGYHEKER EECCCCCCCCCCCCC | 27732954 | ||
| 115 | Phosphorylation | SGMPFYGYHEKERHF CCCCCCCCCCCCCEE | 27732954 | ||
| 126 | Phosphorylation | ERHFMKIYLYNPTMV CCEEEEEEECCHHHH | 26503514 | ||
| 128 | Phosphorylation | HFMKIYLYNPTMVKR EEEEEEECCHHHHHH | 22817900 | ||
| 142 | Phosphorylation | RICELLQSGAIMNKF HHHHHHHCCCHHHCC | - | ||
| 188 | Ubiquitination | KFRKARRKSNTLHAT HHHHHHHCCCCCCCC | - | ||
| 203 | Phosphorylation | GSCKNHLSGNSLADT CCCCCCCCCCCHHHH | 27732954 | ||
| 206 | Phosphorylation | KNHLSGNSLADTLFR CCCCCCCCHHHHHHH | 27732954 | ||
| 210 | Phosphorylation | SGNSLADTLFRWEQD CCCCHHHHHHHCCCC | 27732954 | ||
| 300 | Ubiquitination | PATESEKKFQKRLQE CCCHHHHHHHHHHHH | - | ||
| 368 | O-linked_Glycosylation | KESSKGHTRHKVEEA CCCCCCCCCHHHHHH | 30379171 | ||
| 400 | Phosphorylation | QPLTQRLSESPVFMD HHHHHHHHCCCCCCC | 27732954 | ||
| 402 | Phosphorylation | LTQRLSESPVFMDSS HHHHHHCCCCCCCCC | 22210691 | ||
| 408 | Phosphorylation | ESPVFMDSSPDEALV CCCCCCCCCHHHHHH | 27732954 | ||
| 409 | Phosphorylation | SPVFMDSSPDEALVH CCCCCCCCHHHHHHH | 27732954 | ||
| 423 | Phosphorylation | HLLAGLESDGYRGER HHHHCCCCCCCCCCC | 22210691 | ||
| 426 | Phosphorylation | AGLESDGYRGERNRM HCCCCCCCCCCCCCC | 22210691 | ||
| 435 | Phosphorylation | GERNRMPSPCRSFGN CCCCCCCCCCCCCCC | 23898821 | ||
| 445 | Phosphorylation | RSFGNNKYPQNSDDE CCCCCCCCCCCCCCC | 25159151 | ||
| 449 | Phosphorylation | NNKYPQNSDDEENEP CCCCCCCCCCCCCCC | 28985074 | ||
| 470 | Phosphorylation | MELSLVMSQRWDSNI HHHHHHHHHHCCCCH | 18491316 | ||
| 545 | Phosphorylation | NENSRTHSSVIATSK CCCCCCCCCCEEECC | - | ||
| 556 | Acetylation | ATSKLSVKPSIFHKD EECCCCCCCCEECCC | 25953088 | ||
| 582 | Phosphorylation | ITFQCKHTSALSSHV EEEEECCHHHHHHHC | 22817900 | ||
| 583 | Phosphorylation | TFQCKHTSALSSHVL EEEECCHHHHHHHCC | 22817900 | ||
| 621 | Phosphorylation | VTSFTNESTYSMKYP CCCCCCCCCCCCCCC | 29759185 | ||
| 654 | Phosphorylation | KEILPVSSCESSIFD CCEECHHHCCCCCCC | - | ||
| 688 | Phosphorylation | IRKIEKDSPFIHMHR CEECCCCCCCCEEEC | 28555341 | ||
| 704 | Ubiquitination | PNENTLGKNSFNFSD CCCCCCCCCCCCHHH | - | ||
| 819 | Phosphorylation | QKLSPVTYKLQPGNK CCCCCCEEECCCCCC | 22817900 | ||
| 828 | Phosphorylation | LQPGNKPSRLKLNKR CCCCCCCCHHEECCC | 26699800 | ||
| 834 | Acetylation | PSRLKLNKRKLAGHQ CCHHEECCCHHCCCC | 7673937 | ||
| 836 | Acetylation | RLKLNKRKLAGHQET HHEECCCHHCCCCCC | 7673947 | ||
| 850 | Phosphorylation | TSTKSSETGSTKDNF CCCCCCCCCCCCCCC | - | ||
| 852 | Phosphorylation | TKSSETGSTKDNFIQ CCCCCCCCCCCCCCC | - | ||
| 853 | Phosphorylation | KSSETGSTKDNFIQN CCCCCCCCCCCCCCC | - | ||
| 918 | Phosphorylation | GLYGNKYTLRAKRKV ECCCCEEEEEEECEE | 24719451 | ||
| 924 | Acetylation | YTLRAKRKVNYETED EEEEEECEECCCCCC | 21669532 | ||
| 927 | Phosphorylation | RAKRKVNYETEDSES EEECEECCCCCCCCC | 22199227 | ||
| 929 | Phosphorylation | KRKVNYETEDSESSF ECEECCCCCCCCCCC | 22199227 | ||
| 932 | Phosphorylation | VNYETEDSESSFVTH ECCCCCCCCCCCCCC | 22199227 | ||
| 934 | Phosphorylation | YETEDSESSFVTHNS CCCCCCCCCCCCCCC | 22199227 | ||
| 935 | Phosphorylation | ETEDSESSFVTHNSK CCCCCCCCCCCCCCE | 22199227 | ||
| 938 | Phosphorylation | DSESSFVTHNSKISL CCCCCCCCCCCEECC | 22199227 | ||
| 941 | Phosphorylation | SSFVTHNSKISLPHP CCCCCCCCEECCCCC | 22199227 | ||
| 942 | Acetylation | SFVTHNSKISLPHPM CCCCCCCEECCCCCH | 21669532 | ||
| 954 | Phosphorylation | HPMEIGESLDGTLKS CCHHHCCCCCCCHHH | 24719451 | ||
| 960 | Acetylation | ESLDGTLKSRKRRKM CCCCCCHHHHHHHHH | 21669532 | ||
| 968 | Phosphorylation | SRKRRKMSKKLPPVI HHHHHHHHHCCCHHH | - | ||
| 970 | Acetylation | KRRKMSKKLPPVIIK HHHHHHHCCCHHHHH | 7258187 | ||
| 1030 | Phosphorylation | FWPKVPDSPATKYPI HCCCCCCCCCCCCCC | 27273156 | ||
| 1033 | Phosphorylation | KVPDSPATKYPIYPL CCCCCCCCCCCCCCC | 29255136 | ||
| 1035 | Phosphorylation | PDSPATKYPIYPLTP CCCCCCCCCCCCCCC | 28450419 | ||
| 1038 | Phosphorylation | PATKYPIYPLTPKKS CCCCCCCCCCCCCCC | 19690332 | ||
| 1041 | Phosphorylation | KYPIYPLTPKKSHRR CCCCCCCCCCCCCCC | 27273156 | ||
| 1075 | Phosphorylation | ENIKRTLSFRKKRSH HHHHHHHHHHHHCCC | 23403867 | ||
| 1081 | Phosphorylation | LSFRKKRSHAILSPP HHHHHHCCCEEECCC | 27732954 | ||
| 1086 | Phosphorylation | KRSHAILSPPSPSYN HCCCEEECCCCCCCC | 27732954 | ||
| 1089 | Phosphorylation | HAILSPPSPSYNAET CEEECCCCCCCCCCC | 30108239 | ||
| 1091 | Phosphorylation | ILSPPSPSYNAETED EECCCCCCCCCCCCC | 27732954 | ||
| 1092 | Phosphorylation | LSPPSPSYNAETEDC ECCCCCCCCCCCCCC | 27732954 | ||
| 1096 | Phosphorylation | SPSYNAETEDCDLNY CCCCCCCCCCCCCCH | 27732954 | ||
| 1114 | Phosphorylation | MSKLGFLSERSTSPI HHHHCCCCCCCCCCC | 30266825 | ||
| 1117 | Phosphorylation | LGFLSERSTSPINSS HCCCCCCCCCCCCCC | 23403867 | ||
| 1118 | Phosphorylation | GFLSERSTSPINSSP CCCCCCCCCCCCCCC | 30108239 | ||
| 1119 | Phosphorylation | FLSERSTSPINSSPP CCCCCCCCCCCCCCC | 25849741 | ||
| 1123 | Phosphorylation | RSTSPINSSPPRCWS CCCCCCCCCCCCCCC | 25849741 | ||
| 1124 | Phosphorylation | STSPINSSPPRCWSP CCCCCCCCCCCCCCC | 23403867 | ||
| 1130 | Phosphorylation | SSPPRCWSPTDPRAE CCCCCCCCCCCCCHH | 30108239 | ||
| 1132 | Phosphorylation | PPRCWSPTDPRAEEI CCCCCCCCCCCHHHH | 30108239 | ||
| 1156 | Phosphorylation | LFKGPNVYKKTVNSR HHCCCCCHHHHHHHH | - | ||
| 1185 | Phosphorylation | KAKLANPSIVTKKRN HHHHCCHHHHCCCCC | - | ||
| 1224 | Phosphorylation | KGTSRKHTTLKDEKI CCCCCCCCCCCCHHH | 23403867 | ||
| 1225 | Phosphorylation | GTSRKHTTLKDEKIK CCCCCCCCCCCHHHH | 23403867 | ||
| 1227 | Acetylation | SRKHTTLKDEKIKSQ CCCCCCCCCHHHHCC | 26210075 | ||
| 1249 | Phosphorylation | VLKHQNVSEFASSSG EEEECCHHHHHHCCC | 24260401 | ||
| 1253 | Phosphorylation | QNVSEFASSSGGSQL CCHHHHHHCCCCCEE | 28450419 | ||
| 1254 | Phosphorylation | NVSEFASSSGGSQLL CHHHHHHCCCCCEEE | 28450419 | ||
| 1255 | Phosphorylation | VSEFASSSGGSQLLF HHHHHHCCCCCEEEE | 28450419 | ||
| 1258 | Phosphorylation | FASSSGGSQLLFKQK HHHCCCCCEEEEEEC | 29759185 | ||
| 1263 | Ubiquitination | GGSQLLFKQKDMPLM CCCEEEEEECCCCCC | - | ||
| 1281 | Phosphorylation | VDHPLSASLPTGINA CCCCHHHCCCCCCCH | - | ||
| 1343 | Phosphorylation | VQRPHNQSAMFTLKE CCCCCCCCCCEEECC | 24247654 | ||
| 1347 | Phosphorylation | HNQSAMFTLKESTLI CCCCCCEEECCHHHH | 24247654 | ||
| 1351 | Phosphorylation | AMFTLKESTLIQKNI CCEEECCHHHHHHHH | 29083192 | ||
| 1352 | Phosphorylation | MFTLKESTLIQKNIF CEEECCHHHHHHHHH | 29083192 | ||
| 1399 | Acetylation | NYLSSIGKLSEYRNS HHHHHHHHHHHHHHH | 25953088 | ||
| 1406 | Phosphorylation | KLSEYRNSLESKLDQ HHHHHHHHHHHHHHH | 28348404 | ||
| 1410 | Ubiquitination | YRNSLESKLDQAYTP HHHHHHHHHHHHCCC | - | ||
| 1436 | Phosphorylation | IVCIAEQSKHSETCS EEEEEECCCCCCCCC | 30576142 | ||
| 1461 | Phosphorylation | MPNNCFVTSLRSPIK CCCCEEEHHCCCHHH | 30576142 | ||
| 1462 | Phosphorylation | PNNCFVTSLRSPIKQ CCCEEEHHCCCHHHH | 30576142 | ||
| 1504 | Acetylation | SEAISQTKALSQCKN HHHHHHHHHHHHHCC | 19813095 | ||
| 1515 | Phosphorylation | QCKNRNVSTPSAFGE HHCCCCCCCCHHCCC | 22210691 | ||
| 1546 | Phosphorylation | QKAQNANTTQDPLSN HHHHHCCCCCCCCCC | 29978859 | ||
| 1547 | Phosphorylation | KAQNANTTQDPLSNK HHHHCCCCCCCCCCC | 29978859 | ||
| 1552 | Phosphorylation | NTTQDPLSNKHQPNK CCCCCCCCCCCCCCC | 29978859 | ||
| 1574 | Phosphorylation | HNKANKRTRSVTSPR CCCCCCCCCCCCCCC | 29978859 | ||
| 1576 | Phosphorylation | KANKRTRSVTSPRKP CCCCCCCCCCCCCCC | 22210691 | ||
| 1578 | Phosphorylation | NKRTRSVTSPRKPRT CCCCCCCCCCCCCCC | 22210691 | ||
| 1579 | Phosphorylation | KRTRSVTSPRKPRTP CCCCCCCCCCCCCCC | 22210691 | ||
| 1582 | Acetylation | RSVTSPRKPRTPRST CCCCCCCCCCCCCCC | 20167786 | ||
| 1589 | Phosphorylation | KPRTPRSTKQKEKIP CCCCCCCCCHHHHCC | 18452278 | ||
| 1603 | Phosphorylation | PKLLKVDSLNLQNSS CHHHCCCCCCCCCCH | - | ||
| 1693 | Ubiquitination | FPGQAIEKNEFLSHD CCCCHHHHCCCCCCC | - | ||
| 1720 | Phosphorylation | DSASWIRSGTLSPEI CCHHHHHCCCCCHHH | 30266825 | ||
| 1722 | Phosphorylation | ASWIRSGTLSPEIFE HHHHHCCCCCHHHHH | 30266825 | ||
| 1724 | Phosphorylation | WIRSGTLSPEIFEKS HHHCCCCCHHHHHHC | 29255136 | ||
| 1755 | Phosphorylation | FHPLTTRSNSIMDSF CCCCCCCCCCHHHHH | 24719451 | ||
| 1757 | Phosphorylation | PLTTRSNSIMDSFCV CCCCCCCCHHHHHHH | 27732954 | ||
| 1761 | Phosphorylation | RSNSIMDSFCVQQAE CCCCHHHHHHHHHHH | 27732954 | ||
| 1796 | Phosphorylation | SLPQPNNSDWIQGHT CCCCCCCCCCCCCCC | 25159151 | ||
| 1842 | Phosphorylation | EDLELYVSRNNDMLT ECCEEEEECCCCCCC | 16094384 | ||
| 1849 | Phosphorylation | SRNNDMLTPTPDSSP ECCCCCCCCCCCCCC | 29255136 | ||
| 1851 | Phosphorylation | NNDMLTPTPDSSPRS CCCCCCCCCCCCCCC | 29255136 | ||
| 1854 | Phosphorylation | MLTPTPDSSPRSTSS CCCCCCCCCCCCCCC | 29255136 | ||
| 1855 | Phosphorylation | LTPTPDSSPRSTSSP CCCCCCCCCCCCCCC | 29255136 | ||
| 1858 | Phosphorylation | TPDSSPRSTSSPSQS CCCCCCCCCCCCCCC | 30576142 | ||
| 1863 | Phosphorylation | PRSTSSPSQSKNGSF CCCCCCCCCCCCCCC | 30576142 | ||
| 1865 | Phosphorylation | STSSPSQSKNGSFTP CCCCCCCCCCCCCCC | 30576142 | ||
| 1960 | Phosphorylation | KTAFSAMTQNPRPGS HHHHHHHHCCCCCCC | 28450419 | ||
| 1967 | Phosphorylation | TQNPRPGSPLRSGQG HCCCCCCCCCCCCCC | 22617229 | ||
| 1978 | Ubiquitination | SGQGVVNKGSSNSPK CCCCCCCCCCCCCCC | - | ||
| 2028 | Phosphorylation | KLPKTKPTGVVKSAE CCCCCCCCCCCCCCC | - | ||
| 2038 | Phosphorylation | VKSAENFSSSVNPDD CCCCCCCCCCCCCCC | - | ||
| 2056 | Phosphorylation | VPPKMDVSPCILPTT CCCCCCCCCCCCCCC | 28985074 | ||
| 2062 | Phosphorylation | VSPCILPTTAHTKED CCCCCCCCCCCCHHH | 27732954 | ||
| 2063 | Phosphorylation | SPCILPTTAHTKEDV CCCCCCCCCCCHHHC | 27732954 | ||
| 2066 | Phosphorylation | ILPTTAHTKEDVDNS CCCCCCCCHHHCCCC | 27732954 | ||
| 2146 | Phosphorylation | LNGDDRPSSPVEELP CCCCCCCCCCHHHCH | 22199227 | ||
| 2147 | Phosphorylation | NGDDRPSSPVEELPS CCCCCCCCCHHHCHH | 25849741 | ||
| 2171 | Phosphorylation | IKDGIQKSPCSEPQE HCCCCCCCCCCCCCC | 29255136 | ||
| 2174 | Phosphorylation | GIQKSPCSEPQEPLV CCCCCCCCCCCCCEE | 29255136 | ||
| 2183 | Phosphorylation | PQEPLVISPINTRAR CCCCEEEECCCCCCC | 25850435 | ||
| 2187 | Phosphorylation | LVISPINTRARTGKC EEEECCCCCCCCCCC | 26074081 | ||
| 2220 | Phosphorylation | LPEAPGLSPLSTEPK CCCCCCCCCCCCCCC | 29255136 | ||
| 2223 | Phosphorylation | APGLSPLSTEPKTQK CCCCCCCCCCCCHHH | 29255136 | ||
| 2224 | Phosphorylation | PGLSPLSTEPKTQKL CCCCCCCCCCCHHHC | 29255136 | ||
| 2232 | Phosphorylation | EPKTQKLSNKKGSNT CCCHHHCCCCCCCCH | 30631047 | ||
| 2237 | O-linked_Glycosylation | KLSNKKGSNTDTLRR HCCCCCCCCHHHHHH | 30379171 | ||
| 2239 | Phosphorylation | SNKKGSNTDTLRRVL CCCCCCCHHHHHHHH | 30631047 | ||
| 2241 | Phosphorylation | KKGSNTDTLRRVLLT CCCCCHHHHHHHHHH | 30631047 | ||
| 2251 | Ubiquitination | RVLLTQAKNQFAAVN HHHHHHHHHCCCCCC | - | ||
| 2259 | Phosphorylation | NQFAAVNTPQKETSQ HCCCCCCCCCCCCCC | 25159151 | ||
| 2298 | Phosphorylation | LHEIQNLTLISVELH HHHHHCCEEEEEEEH | 16094384 | ||
| 2363 | Phosphorylation | SQDIRYQTPLLIRSG CCCCCCCCCEEEECC | - | ||
| 2378 | Phosphorylation | ITGLEVTYAADEKAL CCCCEEEEECCHHHH | - | ||
| 2410 | Phosphorylation | GYEIQMHSWGYLLQR CCEEEEHHHHHHHHH | 23663014 | ||
| 2413 | Phosphorylation | IQMHSWGYLLQRAAA EEEHHHHHHHHHHHH | 23663014 | ||
| 2422 | Phosphorylation | LQRAAALSIDLCRMI HHHHHHHHHHHHHHH | 22210691 | ||
| 2430 | Phosphorylation | IDLCRMISRVPDDKI HHHHHHHHCCCCHHH | 22210691 | ||
| 2430 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 2508 | Ubiquitination | LSDWFDNKTDLYRWK HHHHCCCCCCHHHHH | 21890473 | ||
| 2508 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 2522 | Phosphorylation | KMVDHYVSRVRGNLQ HHHHHHHHHHHHHHH | 16094384 | ||
| 2576 | Phosphorylation | RIAKPMNYIPVTPSV HHCCCCCCCCCCCCH | 29978859 | ||
| 2580 | Phosphorylation | PMNYIPVTPSVQQRS CCCCCCCCCCHHHHH | 29978859 | ||
| 2582 | Phosphorylation | NYIPVTPSVQQRSQM CCCCCCCCHHHHHCC | 29978859 | ||
| 2696 | Phosphorylation | MLEEILKTRFMVKQS HHHHHHHHHHHHHHH | 29083192 | ||
| 2703 | Phosphorylation | TRFMVKQSMKAYKQD HHHHHHHHHHHHHHH | 29083192 | ||
| 2714 | Phosphorylation | YKQDRALSRMLDARQ HHHHHHHHHHHHHHH | 21955146 | ||
| 2822 | Acetylation | PVKLKFEKVYLPCVL CCCCEEEEEECCHHH | 7340085 | ||
| 2831 | Phosphorylation | YLPCVLQTKKRYVGY ECCHHHHCCCHHCCE | - | ||
| 2853 | Ubiquitination | KDPVFDAKGIETVRR CCCCCCCCCCHHHCC | - | ||
| 2868 | Methylation | DSCPAVSKILERSLK CCCHHHHHHHHHHHH | 23644510 | ||
| 2884 | Phosphorylation | LFETRDISLIKQYVQ HHHCCCHHHHHHHHH | 24719451 | ||
| 2936 | Phosphorylation | ELTRKMLTYDRRSEP HHHHHHHHCCCCCCC | 24719451 | ||
| 2937 | Phosphorylation | LTRKMLTYDRRSEPQ HHHHHHHCCCCCCCC | 24719451 | ||
| 2984 | Phosphorylation | TLRLNATYYITKQIL CCCCCCEEEEHHHHH | - | ||
| 2985 | Phosphorylation | LRLNATYYITKQILP CCCCCEEEEHHHHHH | - | ||
| 3087 | Ubiquitination | EQLVKICKNCTGCFD HHHHHHHHCCCCCCC | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
| 1075 | S | Phosphorylation | Kinase | CHEK2 | O96017 | GPS |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of REV3L_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of REV3L_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MD2L2_HUMAN | MAD2L2 | physical | 11485998 | |
| REV1_HUMAN | REV1 | physical | 21926160 | |
| MD2L2_HUMAN | MAD2L2 | physical | 21926160 | |
| MD2L2_HUMAN | MAD2L2 | physical | 20164194 | |
| RL14_HUMAN | RPL14 | physical | 26344197 | |
| GPR27_HUMAN | GPR27 | genetic | 25113059 | |
| RIR1_HUMAN | RRM1 | genetic | 25113059 | |
| CFLAR_HUMAN | CFLAR | genetic | 25113059 | |
| LMTK3_HUMAN | LMTK3 | genetic | 25113059 | |
| CCR6_HUMAN | CCR6 | genetic | 25113059 | |
| CAC1A_HUMAN | CACNA1A | genetic | 25113059 | |
| COPZ1_HUMAN | COPZ1 | genetic | 25113059 | |
| CDY1_HUMAN | CDY1 | genetic | 25113059 | |
| CSAD_HUMAN | CSAD | genetic | 25113059 | |
| A1BG_HUMAN | A1BG | genetic | 25113059 | |
| THIO_HUMAN | TXN | genetic | 25113059 | |
| MOT10_HUMAN | SLC16A10 | genetic | 25113059 | |
| ATAD1_HUMAN | ATAD1 | genetic | 25113059 | |
| RFXAP_HUMAN | RFXAP | genetic | 25113059 | |
| F107A_HUMAN | FAM107A | genetic | 25113059 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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