GPR27_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GPR27_HUMAN
• UniProt AC: Q9NS67
• Protein Name: Probable G-protein coupled receptor 27
• Gene Name: GPR27
• Organism: Homo sapiens (Human).
• Sequence Length: 375
• Subcellular Localization: Cell membrane; Multi-pass membrane protein.
• Protein Description: Orphan receptor. Possible candidate for amine-like G-protein coupled receptor..
• Protein Sequence: MANASEPGGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDDEDAPCALEQRPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLLLWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPRTTQATHPCDLKGIGL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	N-linked_Glycosylation	-----MANASEPGGS -----CCCCCCCCCC	42.58	UniProtKB CARBOHYD
5	Phosphorylation	---MANASEPGGSGG ---CCCCCCCCCCCH	44.10	23025827

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GPR27_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GPR27_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GPR27_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of GPR27_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.