CSAD_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CSAD_HUMAN
• UniProt AC: Q9Y600
• Protein Name: Cysteine sulfinic acid decarboxylase
• Gene Name: CSAD
• Organism: Homo sapiens (Human).
• Sequence Length: 493
• Protein Sequence: MADSEALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLRKLRALVGWSSGDGIFCPGGSISNMYAVNLARYQRYPDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRVVKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCFWFVPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSALTCADMDFLLNELERLGQDL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2 (in isoform 3)	Phosphorylation	-	29.09	25022875
7 (in isoform 3)	Phosphorylation	-	2.31	25022875
8 (in isoform 3)	Phosphorylation	-	34.05	25022875
12 (in isoform 3)	Phosphorylation	-	45.08	25022875
13 (in isoform 3)	Phosphorylation	-	28.97	25022875
16 (in isoform 3)	Phosphorylation	-	9.98	25022875
23 (in isoform 3)	Phosphorylation	-	10.85	25022875
42	Ubiquitination	KGTSVSQKVCEWKEP HCCCCCHHHHCCCCH	41.15	-
53	Ubiquitination	WKEPEELKQLLDLEL CCCHHHHHHHHHHHH	42.03	-
81	Phosphorylation	CRAVIRYSVKTGHPR HHHHHHHHHHCCCHH	13.80	24719451
84	Phosphorylation	VIRYSVKTGHPRFFN HHHHHHHCCCHHHHH	38.27	24719451
108	Phosphorylation	ALAGRIITESLNTSQ HHHHHHHHCCCCCCC	19.70	24719451
111	Phosphorylation	GRIITESLNTSQYTY HHHHHCCCCCCCCEE	7.07	24719451
158	Phosphorylation	GGSISNMYAVNLARY CCCHHHCEEEHHHHH	16.20	18083107
305	N6-(pyridoxal phosphate)lysine	SVAWNPHKLLAAGLQ HCCCCHHHHHHHHHH	46.59	-
305	Other	SVAWNPHKLLAAGLQ HCCCCHHHHHHHHHH	46.59	-
352	Ubiquitination	VALDTGDKVVQCGRR EEECCCCCEEECCCC	45.72	-
442	Ubiquitination	SKVAPVLKERMVKEG HHHHHHHHHHHCCCC	43.43	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CSAD_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CSAD_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CSAD_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CSAD_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• DB00151: L-Cysteine