PXC3_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PXC3_ARATH
• UniProt AC: O22938
• Protein Name: Leucine-rich repeat receptor-like tyrosine-protein kinase PXC3 {ECO:0000305}
• Gene Name: PXC3 {ECO:0000303|PubMed:23815750}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 890
• Subcellular Localization: Cell membrane; Single-pass type I membrane protein.
• Protein Description: Leucine-rich repeat receptor-like protein kinase that may play a role in vascular tissues development..
• Protein Sequence: MTFWCMSILLIVGFLSKSELCEAQLSDEATLVAINRELGVPGWSSNGTDYCTWVGLKCGVNNSFVEMLDLSGLQLRGNVTLISDLRSLKHLDLSGNNFNGRIPTSFGNLSELEFLDLSLNRFVGAIPVEFGKLRGLRAFNISNNLLVGEIPDELKVLERLEEFQVSGNGLNGSIPHWVGNLSSLRVFTAYENDLVGEIPNGLGLVSELELLNLHSNQLEGKIPKGIFEKGKLKVLVLTQNRLTGELPEAVGICSGLSSIRIGNNELVGVIPRTIGNISGLTYFEADKNNLSGEIVAEFSKCSNLTLLNLAANGFAGTIPTELGQLINLQELILSGNSLFGEIPKSFLGSGNLNKLDLSNNRLNGTIPKELCSMPRLQYLLLDQNSIRGDIPHEIGNCVKLLQLQLGRNYLTGTIPPEIGRMRNLQIALNLSFNHLHGSLPPELGKLDKLVSLDVSNNLLTGSIPPLLKGMMSLIEVNFSNNLLNGPVPVFVPFQKSPNSSFLGNKELCGAPLSSSCGYSEDLDHLRYNHRVSYRIVLAVIGSGVAVFVSVTVVVLLFMMREKQEKAAAKNVDVEENVEDEQPAIIAGNVFLENLKQGIDLDAVVKATMKESNKLSTGTFSSVYKAVMPSGMIVSVKKLKSMDRAISHHQNKMIRELERLSKLCHDHLVRPIGFVIYEDVALLLHQHLPNGNLTQLIHESTKKPEYQPDWPMRLSIAVGAAEGLAFLHQVAIIHLDVSSSNVLLDSGYKAVLGEIEISKLLDPSRGTASISSVAGSFGYIPPEYAYTMQVTAPGNVYSYGVVLLEILTSRAPVEEEFGEGVDLVKWVHGASARGETPEQILDAKLSTVSFAWRREMLAALKVALLCTDITPAKRPKMKKVVEMLQEVKQIK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
46	N-linked_Glycosylation	GVPGWSSNGTDYCTW CCCCCCCCCCCCCCE		-
61	N-linked_Glycosylation	VGLKCGVNNSFVEML EECEECCCCCHHHHH		-
78	N-linked_Glycosylation	SGLQLRGNVTLISDL CCCEEECCEEEEECC		-
108	N-linked_Glycosylation	RIPTSFGNLSELEFL CCCCCCCCHHHHHHH		-
140	N-linked_Glycosylation	LRGLRAFNISNNLLV CCCCEEEEECCCEEE		-
171	N-linked_Glycosylation	QVSGNGLNGSIPHWV CCCCCCCCCCCCHHH		-
180	N-linked_Glycosylation	SIPHWVGNLSSLRVF CCCHHHCCHHHCEEE		-
276	N-linked_Glycosylation	VIPRTIGNISGLTYF EEECCCCCCCCCEEE		-
289	N-linked_Glycosylation	YFEADKNNLSGEIVA EEEECCCCCCHHHHE		-
303	N-linked_Glycosylation	AEFSKCSNLTLLNLA EEEHHCCCCCHHHHH		-
363	N-linked_Glycosylation	DLSNNRLNGTIPKEL CCCCCCCCCCCCHHH		-
429	N-linked_Glycosylation	RNLQIALNLSFNHLH CCHHHHHHCCHHHCC		-
477	N-linked_Glycosylation	MMSLIEVNFSNNLLN HHHHEEEECCCCCCC		-
498	N-linked_Glycosylation	VPFQKSPNSSFLGNK EECCCCCCCCCCCCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PXC3_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PXC3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PXC3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SERK2_ARATH	SERK2	physical	21423366
Y5838_ARATH	BIR1	physical	21423366
SERK1_ARATH	SERK1	physical	21423366
Y5639_ARATH	AT5G63930	physical	21423366
PXC3_ARATH	AT2G41820	physical	21423366
Y5129_ARATH	AT5G10290	physical	21423366
HHP2_ARATH	HHP2	physical	24833385
HHP4_ARATH	HHP4	physical	24833385
UBC32_ARATH	UBC32	physical	24833385
UBC34_ARATH	UBC34	physical	24833385
POP3_ARATH	HS1	physical	24833385
NAC89_ARATH	NAC089	physical	24833385
ACBP6_ARATH	ACBP6	physical	24833385
GSTUJ_ARATH	GSTU19	physical	24833385
SERK2_ARATH	SERK2	physical	24833385
TRXH5_ARATH	TRX5	physical	24833385
DHAR1_ARATH	DHAR1	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
SBP3_ARATH	MAPR2	physical	24833385
MSBP2_ARATH	MAPR3	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
PPA3_ARATH	PAP3	physical	24833385
RAH1C_ARATH	RABH1c	physical	24833385
SRF1_ARATH	SRF1	physical	24833385
PAM74_ARATH	AT5G59650	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385
BET12_ARATH	ATBET12	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.