| UniProt ID | MET23_HUMAN | |
|---|---|---|
| UniProt AC | Q86XA0 | |
| Protein Name | Methyltransferase-like protein 23 | |
| Gene Name | METTL23 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 190 | |
| Subcellular Localization |
Cytoplasm . Membrane Single-pass membrane protein . When overexpressed, detected in cytoplasmic membrane-like structures. |
|
| Protein Description | Probable methyltransferase.. | |
| Protein Sequence | MYVWPCAVVLAQYLWFHRRSLPGKAILEIGAGVSLPGILAAKCGAEVILSDSSELPHCLEVCRQSCQMNNLPHLQVVGLTWGHISWDLLALPPQDIILASDVFFEPEDFEDILATIYFLMHKNPKVQLWSTYQVRSADWSLEALLYKWDMKCVHIPLESFDADKEDIAESTLPGRHTVEMLVISFAKDSL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MYVWPCAVV ------CCHHHHHHH | 15.95 | 24043423 | |
| 164 | Ubiquitination | LESFDADKEDIAEST HHHCCCCHHHHHHCC | 60.03 | - | |
| 177 | Phosphorylation | STLPGRHTVEMLVIS CCCCCCCEEEEEEEE | 19.46 | - | |
| 184 | Phosphorylation | TVEMLVISFAKDSL- EEEEEEEEEHHHCC- | 16.21 | - | |
| 189 | Phosphorylation | VISFAKDSL------ EEEEHHHCC------ | 34.96 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MET23_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MET23_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MET23_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| BAG6_HUMAN | BAG6 | physical | 23349634 | |
| CASPE_HUMAN | CASP14 | physical | 23349634 | |
| TCPG_HUMAN | CCT3 | physical | 23349634 | |
| CYTA_HUMAN | CSTA | physical | 23349634 | |
| DNJA1_HUMAN | DNAJA1 | physical | 23349634 | |
| DNJA2_HUMAN | DNAJA2 | physical | 23349634 | |
| DJB11_HUMAN | DNAJB11 | physical | 23349634 | |
| GANAB_HUMAN | GANAB | physical | 23349634 | |
| ENPL_HUMAN | HSP90B1 | physical | 23349634 | |
| GRP78_HUMAN | HSPA5 | physical | 23349634 | |
| CCAR2_HUMAN | CCAR2 | physical | 23349634 | |
| MT21D_HUMAN | VCPKMT | physical | 23349634 | |
| PDIA6_HUMAN | PDIA6 | physical | 23349634 | |
| S10A7_HUMAN | S100A7 | physical | 23349634 | |
| S10A9_HUMAN | S100A9 | physical | 23349634 | |
| SEP15_HUMAN | SEP15 | physical | 23349634 | |
| SERPH_HUMAN | SERPINH1 | physical | 23349634 | |
| TBB2A_HUMAN | TUBB2A | physical | 23349634 | |
| TBB3_HUMAN | TUBB3 | physical | 23349634 | |
| TBB4A_HUMAN | TUBB4A | physical | 23349634 | |
| TBB6_HUMAN | TUBB6 | physical | 23349634 | |
| UBB_HUMAN | UBB | physical | 23349634 | |
| UBC_HUMAN | UBC | physical | 23349634 | |
| UBL4A_HUMAN | UBL4A | physical | 23349634 | |
| UGGG1_HUMAN | UGGT1 | physical | 23349634 | |
| UGGG2_HUMAN | UGGT2 | physical | 23349634 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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