KRA32_HUMAN - dbPTM
KRA32_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KRA32_HUMAN
UniProt AC Q9BYR7
Protein Name Keratin-associated protein 3-2
Gene Name KRTAP3-2
Organism Homo sapiens (Human).
Sequence Length 98
Subcellular Localization
Protein Description In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins..
Protein Sequence MDCCASRSCSVPTGPATTICSSDKSCRCGVCLPSTCPHTVWLLEPICCDNCPPPCHIPQPCVPTCFLLNSCQPTPGLETLNLTTFTQPCCEPCLPRGC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
21PhosphorylationGPATTICSSDKSCRC
CCCEEEECCCCCCCC
37.41-
22PhosphorylationPATTICSSDKSCRCG
CCEEEECCCCCCCCC
44.65-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KRA32_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KRA32_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KRA32_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KRA32_HUMANKRTAP3-2physical
25416956
KRA92_HUMANKRTAP9-2physical
25416956
DHRS1_HUMANDHRS1physical
25416956
TBC16_HUMANTBC1D16physical
25416956
LCE4A_HUMANLCE4Aphysical
25416956
CE060_HUMANC5orf60physical
25416956
TRI42_HUMANTRIM42physical
25416956
LCE1B_HUMANLCE1Bphysical
25416956
LCE2A_HUMANLCE2Aphysical
25416956
LCE3C_HUMANLCE3Cphysical
25416956
LCE3E_HUMANLCE3Ephysical
25416956
KR122_HUMANKRTAP12-2physical
25416956
KR101_HUMANKRTAP10-1physical
25416956
KR261_HUMANKRTAP26-1physical
25416956

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KRA32_HUMAN

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Related Literatures of Post-Translational Modification

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