CE060_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CE060_HUMAN
• UniProt AC: A6NFR6
• Protein Name: Putative uncharacterized protein C5orf60
• Gene Name: C5orf60
• Organism: Homo sapiens (Human).
• Sequence Length: 353
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MPRAQLPEDSSAVDMDILFPLDSVIGTELCPSPIPQIIHFVLFVVFSLVILIILRLYIPREPSSVPPREEDSENDQAEVGEWLRIGNKYITLKDYRILLKELENLEIYTFLSKKCLKKLSREGSSHHLPRQVRPGPVYKPAPARNHRPRGGRGKASPTSFHVSPRAPLAPLASMPSSVPKTSVESLGSPSSLSSSKPREPLCPLKHPSHQPPASTLSPNPTSSTESLGYLSSLSSSQPPEPLRPLKHPSHKPRGRSLPRRRNPGWVSWSDSMQADSETDTIICPMCKAPERSCPHTWWVPSSPRVIRGVGRCSDPNLGLSWRQEAARAWCHCTSSQFPFKHPNLPTHLPKASF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
27	Phosphorylation	PLDSVIGTELCPSPI ECCCCCCCCCCCCCH	18.05	24275569
63	Phosphorylation	LYIPREPSSVPPREE HHCCCCCCCCCCCCC	38.93	-
64	Phosphorylation	YIPREPSSVPPREED HCCCCCCCCCCCCCC	49.73	-
156	Phosphorylation	RGGRGKASPTSFHVS CCCCCCCCCCCEECC	32.00	-
158	Phosphorylation	GRGKASPTSFHVSPR CCCCCCCCCEECCCC	41.34	-
159	Phosphorylation	RGKASPTSFHVSPRA CCCCCCCCEECCCCC	19.42	-
163	Phosphorylation	SPTSFHVSPRAPLAP CCCCEECCCCCCCCC	10.49	-
176	Phosphorylation	APLASMPSSVPKTSV CCCCCCCCCCCCCCH	35.01	-
177	Phosphorylation	PLASMPSSVPKTSVE CCCCCCCCCCCCCHH	36.25	23403867
181	Phosphorylation	MPSSVPKTSVESLGS CCCCCCCCCHHHCCC	31.75	30622161
182	Phosphorylation	PSSVPKTSVESLGSP CCCCCCCCHHHCCCC	29.98	30622161
185	Phosphorylation	VPKTSVESLGSPSSL CCCCCHHHCCCCHHH	35.56	30622161
188	Phosphorylation	TSVESLGSPSSLSSS CCHHHCCCCHHHCCC	27.23	30622161
190	Phosphorylation	VESLGSPSSLSSSKP HHHCCCCHHHCCCCC	45.68	30622161
191	Phosphorylation	ESLGSPSSLSSSKPR HHCCCCHHHCCCCCC	35.34	30622161
193	Phosphorylation	LGSPSSLSSSKPREP CCCCHHHCCCCCCCC	34.22	30622161
194	Phosphorylation	GSPSSLSSSKPREPL CCCHHHCCCCCCCCC	47.91	30622161
195	Phosphorylation	SPSSLSSSKPREPLC CCHHHCCCCCCCCCC	43.22	30622161
251	Ubiquitination	PLKHPSHKPRGRSLP CCCCCCCCCCCCCCC	40.52	-
262 (in isoform 4)	Phosphorylation	-	37.31	22210691
266 (in isoform 2)	Phosphorylation	-	5.35	22210691
269	Phosphorylation	NPGWVSWSDSMQADS CCCCCCCCHHCCCCC	16.58	21601212
277 (in isoform 4)	Phosphorylation	-	51.77	22210691
281 (in isoform 2)	Phosphorylation	-	3.21	22210691
302	Phosphorylation	HTWWVPSSPRVIRGV CCEECCCCCCEEECC	15.62	29759185
313	Phosphorylation	IRGVGRCSDPNLGLS EECCCCCCCCCCCCC	55.53	30622161
320	Phosphorylation	SDPNLGLSWRQEAAR CCCCCCCCHHHHHHH	20.58	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CE060_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CE060_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CE060_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KR109_HUMAN	KRTAP10-9	physical	25416956
NT2NL_HUMAN	NOTCH2NL	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.