LCE3E_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LCE3E_HUMAN
• UniProt AC: Q5T5B0
• Protein Name: Late cornified envelope protein 3E
• Gene Name: LCE3E
• Organism: Homo sapiens (Human).
• Sequence Length: 92
• Protein Description: Precursors of the cornified envelope of the stratum corneum..
• Protein Sequence: MSCQQNQKQCQPPPKCPSPKCPPKNPVQCLPPASSGCAPSSGGCGPSSEGGCFLNHHRRHHRCRRQRSNSCDRGSGQQGGGSGCCHGSGGCC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
70	Phosphorylation	CRRQRSNSCDRGSGQ HHHHHCCCCCCCCCC	20.74	32645325
82	Phosphorylation	SGQQGGGSGCCHGSG CCCCCCCCCCCCCCC	31.75	-
88	Phosphorylation	GSGCCHGSGGCC--- CCCCCCCCCCCC---	14.35	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LCE3E_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LCE3E_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LCE3E_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KR107_HUMAN	KRTAP10-7	physical	25416956
KR109_HUMAN	KRTAP10-9	physical	25416956
KR101_HUMAN	KRTAP10-1	physical	25416956
KR108_HUMAN	KRTAP10-8	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956
NT2NL_HUMAN	NOTCH2NL	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.