KAPB_SCHPO - dbPTM
KAPB_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KAPB_SCHPO
UniProt AC P40376
Protein Name cAMP-dependent protein kinase catalytic subunit
Gene Name pka1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 512
Subcellular Localization
Protein Description
Protein Sequence MDTTAVASKGSTNVGSSTDTLSTSASLHPSMNAGSVNEYSEQQRHGTNSFNGKPSVHDSVGSDASVSNGHNNHNESSLWTSGIPKALEEATKSKKPDSLVSTSTSGCASAHSVGYQNIDNLIPSPLPESASRSSSQSSHQRHSRDGRGELGSEHGERRSAMDGLRDRHIRKVRVSQLLDLQRRRIRPADHTTKDRYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSNCCTLCGTPDYLAPEIISLKPYNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDLLSHLLQRDITCRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYVPPIQAGMGDSSQFDAYADVATDYGTSEDPEFTSIFKDF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
152PhosphorylationDGRGELGSEHGERRS
CCCCCCCCCHHHHHH		38.7629996109
350PhosphorylationFGFAKRVSTSNCCTL
CCCCCCEECCCCCCC		30.1025720772
351PhosphorylationGFAKRVSTSNCCTLC
CCCCCEECCCCCCCC		22.5425720772
352PhosphorylationFAKRVSTSNCCTLCG
CCCCEECCCCCCCCC		21.9925720772
356PhosphorylationVSTSNCCTLCGTPDY
EECCCCCCCCCCCCC		27.5528889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KAPB_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KAPB_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KAPB_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SCK1_SCHPOsck1genetic
7498728
SCK1_SCHPOsck1genetic
11180454
SCK2_SCHPOsck2genetic
9560431
SCK1_SCHPOsck1genetic
9560431
ESC1_SCHPOesc1genetic
16143612
SRO1_SCHPOsro1physical
18410345
HAP5_SCHPOphp5genetic
11238405
HOG1_SCHPOsty1genetic
20453258
KAPR_SCHPOcgs1physical
21869531
KAPR_SCHPOcgs1physical
21879336
PRZ1_SCHPOprz1genetic
22496451
PYP1_SCHPOpyp1genetic
8832414
PYP2_SCHPOpyp2genetic
8832414
TPS1_SCHPOtps1genetic
9302019
ATF1_SCHPOatf1physical
23640764
RAD24_SCHPOrad24genetic
19584544
RAD25_SCHPOrad25genetic
19584544
SDS23_SCHPOsds23physical
23640764
WIS1_SCHPOwis1genetic
23640764
SDS23_SCHPOsds23genetic
23640764
PHX1_SCHPOphx1genetic
25102102
GAD8_SCHPOgad8genetic
24928510
MSA1_SCHPOmsa1genetic
15166138
NRD1_SCHPOnrd1genetic
15166138
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KAPB_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-356, AND MASSSPECTROMETRY.

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