PHX1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PHX1_SCHPO
• UniProt AC: Q10328
• Protein Name: Homeobox transcription factor phx1
• Gene Name: phx1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 942
• Subcellular Localization: Nucleus .
• Protein Description: Trnascription factor that regulates the expression of the homocitrate synthase (HCS) lys4..
• Protein Sequence: MRSYSNPENGGQINDNINYSEKRPTMLPENLSLSNYDMDSFLGQFPSDNNMQLPHSTYEQHLQGEQQNPTNPNYFPPEFDENKVDWKQEKPKPDAPSFADNNSFDNVNSSKLTNPSPVQPNIVKSESEPANSKQNEVVEATSVEKAKENVAHESGTPESGGSTSAPKSKKQRLTADQLAYLLREFSKDTNPPPAIREKIGRELNIPERSVTIWFQNRRAKSKLISRRQEEERQRILREQRELDSLNQKVSQAFAHEVLSTSPTSPYVGGIAANRQYANTLLPKPTRKTGNFYMKSGPMQSSMEPCIAESDIPIRQSLSSTYYNSLSPNAVPVSSQRKYSASSYSAIPNAMSVSNQAFDVESPPSSYATPLTGIRMPQPESDLYSYPREVSPSSGGYRMFGHSKPSSYKASGPVRPPNMATGHMRTSSEPTSYDSEFYYFSCTLLVIGLWKRLRASPQDLMCFYSPPKKLFAYLIQFQGIQYRIEYSFFVIESIHVFRVEEPLLNELSATASSRDKPAPNEYWLQMDIQLSVPPVFHMITSEGQGNCTDFTEGNQASEVLLHSLMGRATSMFQMLDRVRRASPELGSVIRLQKGLNPHQFLDPQWANQLPRQPDSSVFDHQGRNPPIQGLSHDTSSEYGNKSQFKRLRSTSTPARQDLAQHLLPPKTNTEGLMHAQSVSPITQAMKSANVLEGSSTRLNSYEPSVSSAYPHHNLALNLDNTQFGELGTSNISYPLSAPSDVGSLPRASNSPSRPVMHPNTQGINTEIKDMAAQFPNSQTGGLTPNSWSMNTNVSVPFTTQNREFGGIGSSSISTTMNAPSQQLSQVPFGDVSLATENSVPSYGFEVPSEESVYAQARTNSSVSAGVAPRLFIQTPSIPLASSAGQDSNLIEKSSSGGVYASQPGASGYLSHDQSGSPFEDVYSPSAGIDFQKLRGQQFSPDMQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
97	Phosphorylation	KPKPDAPSFADNNSF CCCCCCCCCCCCCCC		21712547
103	Phosphorylation	PSFADNNSFDNVNSS CCCCCCCCCCCCCHH		24763107
116	Phosphorylation	SSKLTNPSPVQPNIV HHHCCCCCCCCCCCC		29996109
154	Phosphorylation	KENVAHESGTPESGG HHHCCCCCCCCCCCC		21712547
156	Phosphorylation	NVAHESGTPESGGST HCCCCCCCCCCCCCC		29996109
159	Phosphorylation	HESGTPESGGSTSAP CCCCCCCCCCCCCCC		24763107
260	Phosphorylation	FAHEVLSTSPTSPYV HHHHHHCCCCCCCCC		29996109
261	Phosphorylation	AHEVLSTSPTSPYVG HHHHHCCCCCCCCCC		29996109
263	Phosphorylation	EVLSTSPTSPYVGGI HHHCCCCCCCCCCCC		25720772
264	Phosphorylation	VLSTSPTSPYVGGIA HHCCCCCCCCCCCCH		25720772
326	Phosphorylation	STYYNSLSPNAVPVS HHCCCCCCCCCCCCC		27738172
361	Phosphorylation	NQAFDVESPPSSYAT CCCCCCCCCCHHCCC		27738172
390	Phosphorylation	YSYPREVSPSSGGYR CCCCCCCCCCCCCCC		29996109
392	Phosphorylation	YPREVSPSSGGYRMF CCCCCCCCCCCCCCC		29996109
676	Phosphorylation	EGLMHAQSVSPITQA CCCCCCCCCCHHHHH		29996109
678	Phosphorylation	LMHAQSVSPITQAMK CCCCCCCCHHHHHHH		29996109
747	Phosphorylation	VGSLPRASNSPSRPV CCCCCCCCCCCCCCC		29996109
749	Phosphorylation	SLPRASNSPSRPVMH CCCCCCCCCCCCCCC		29996109
913	Phosphorylation	GYLSHDQSGSPFEDV CCCCCCCCCCCCCCC		27738172
922	Phosphorylation	SPFEDVYSPSAGIDF CCCCCCCCCCCCCCH		27738172
938	Phosphorylation	KLRGQQFSPDMQ--- HHCCCCCCCCCC---		24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PHX1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PHX1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PHX1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PDC1_SCHPO	SPAC13A11.06	genetic	25102102
PDC4_SCHPO	SPAC3G9.11c	genetic	25102102
RT06_SCHPO	mrp17	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.