IFT43_HUMAN - dbPTM
IFT43_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID IFT43_HUMAN
UniProt AC Q96FT9
Protein Name Intraflagellar transport protein 43 homolog
Gene Name IFT43
Organism Homo sapiens (Human).
Sequence Length 208
Subcellular Localization Cytoplasm, cytoskeleton . Cell projection, cilium . Associated with microtubules.
Protein Description Component of IFT complex A (IFT-A) involved in retrograde ciliary transport along microtubules from the ciliary tip to the base..
Protein Sequence MEDLLDLDEELRYSLATSRAKMGRRAQQESAQAENHLNGKNSSLTLTGETSSAKLPRCRQGGWAGDSVKASKFRRKASEEIEDFRLRPQSLNGSDYGGDIPIIPDLEEVQEEDFVLQVAAPPSIQIKRVMTYRDLDNDLMKYSAIQTLDGEIDLKLLTKVLAPEHEVREDDVGWDWDHLFTEVSSEVLTEWDPLQTEKEDPAGQARHT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
1Acetylation-------MEDLLDLD
-------CCHHHCCC		9.0222814378
13PhosphorylationDLDEELRYSLATSRA
CCCHHHHHHHHHHHH		22.2128796482
14PhosphorylationLDEELRYSLATSRAK
CCHHHHHHHHHHHHH		12.7028796482
43PhosphorylationHLNGKNSSLTLTGET
HHCCCCCCEEEECCC		34.4628857561
43 (in isoform 2)Phosphorylation-34.4627251275
51PhosphorylationLTLTGETSSAKLPRC
EEEECCCCCCCCCCC		24.8128555341
67PhosphorylationQGGWAGDSVKASKFR
CCCCCCHHHHHHHHH		25.3023401153
67 (in isoform 2)Phosphorylation-25.3027251275
69UbiquitinationGWAGDSVKASKFRRK
CCCCHHHHHHHHHHH		51.39-
71PhosphorylationAGDSVKASKFRRKAS
CCHHHHHHHHHHHHH		26.9826074081
76UbiquitinationKASKFRRKASEEIED
HHHHHHHHHHHHHHH		52.59-
78PhosphorylationSKFRRKASEEIEDFR
HHHHHHHHHHHHHHC		38.5029255136
131PhosphorylationIQIKRVMTYRDLDND
EEEEEEEEHHHCCCH		16.73-
132PhosphorylationQIKRVMTYRDLDNDL
EEEEEEEHHHCCCHH		5.52-
147 (in isoform 2)Phosphorylation-22.2427642862
159UbiquitinationIDLKLLTKVLAPEHE
CCHHHHHHHHCCCCC		34.9121890473
159 (in isoform 1)Ubiquitination-34.9121890473
159UbiquitinationIDLKLLTKVLAPEHE
CCHHHHHHHHCCCCC		34.9121890473
164 (in isoform 2)Ubiquitination-47.2621890473
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of IFT43_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of IFT43_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of IFT43_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
IF122_HUMANIFT122physical
28514442
TT21B_HUMANTTC21Bphysical
28514442
WDR35_HUMANWDR35physical
28514442
CK074_HUMANC11orf74physical
28514442
WDR19_HUMANWDR19physical
28514442
IF140_HUMANIFT140physical
28514442
TULP3_HUMANTULP3physical
28514442
TYK2_HUMANTYK2physical
28514442
SENP8_HUMANSENP8physical
28514442
BBS1_HUMANBBS1physical
28514442
TCAL1_HUMANTCEAL1physical
28514442
UBP11_HUMANUSP11physical
28514442
MYO9B_HUMANMYO9Bphysical
28514442
UBP7_HUMANUSP7physical
28514442
TT21B_HUMANTTC21Bphysical
27173435
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
614099Cranioectodermal dysplasia 3 (CED3)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of IFT43_HUMAN

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Related Literatures of Post-Translational Modification

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