ZN669_HUMAN - dbPTM
ZN669_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN669_HUMAN
UniProt AC Q96BR6
Protein Name Zinc finger protein 669
Gene Name ZNF669
Organism Homo sapiens (Human).
Sequence Length 464
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation..
Protein Sequence MVSGLRLASRSGEEGWLKPAVARLGPPRHRLRNLRTESPWRSRGSVLFCSGPGRAGRAAEPLHPVCTCGRHFRRPEPCREPLASPIQDSVAFEDVAVNFTQEEWALLDSSQKNLYREVMQETCRNLASVGSQWKDQNIEDHFEKPGKDIRNHIVQRLCESKEDGQYGEVVSQIPNLDLNENISTGLKPCECSICGKVFVRHSLLNRHILAHSGYKPYGEKQYKCEQCGKFFVSVPGVRRHMIMHSGNPAYKCTICGKAFYFLNSVERHQRTHTGEKPYKCKQCGKAFTVSGSCLIHERTHTGEKPYECKECGKTFRFSCSFKTHERTHTGERPYKCTKCDKAFSCSTSLRYHGSIHTGERPYECKQCGKAFSRLSSLCNHRSTHTGEKPYECKQCDQAFSRLSSLHLHERIHTGEKPYECKKCGKAYTRSSHLTRHERSHDIEAGCSDSAYNPSTLGGQGVWIA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
11PhosphorylationGLRLASRSGEEGWLK
CCEECCCCCCCCCCC		48.32-
48UbiquitinationRSRGSVLFCSGPGRA
CCCCCEEEECCCCCC		2.6729967540
58UbiquitinationGPGRAGRAAEPLHPV
CCCCCCCCCCCCCCC		18.4329967540
67PhosphorylationEPLHPVCTCGRHFRR
CCCCCCCCCCCCCCC		20.4418767875
100PhosphorylationEDVAVNFTQEEWALL
CCEEECCCHHHHHCC		29.84-
122PhosphorylationYREVMQETCRNLASV
HHHHHHHHHHHHHHH		10.40-
128PhosphorylationETCRNLASVGSQWKD
HHHHHHHHHCHHHHC		30.1229978859
131PhosphorylationRNLASVGSQWKDQNI
HHHHHHCHHHHCCCH		30.6129978859
134UbiquitinationASVGSQWKDQNIEDH
HHHCHHHHCCCHHHH		41.6229967540
144UbiquitinationNIEDHFEKPGKDIRN
CHHHHCCCCCHHHHH		59.1129967540
147AcetylationDHFEKPGKDIRNHIV
HHCCCCCHHHHHHHH		59.5125953088
181UbiquitinationPNLDLNENISTGLKP
CCCCCCCCCCCCCCC		32.2222505724
212PhosphorylationNRHILAHSGYKPYGE
HCHHHHCCCCCCCCC		37.9127134283
214PhosphorylationHILAHSGYKPYGEKQ
HHHHCCCCCCCCCCE		16.2929214152
218UbiquitinationHSGYKPYGEKQYKCE
CCCCCCCCCCEEEEC		44.1222505724
245PhosphorylationRRHMIMHSGNPAYKC
HHEEEECCCCCCEEE		23.9229214152
250PhosphorylationMHSGNPAYKCTICGK
ECCCCCCEEEEECCC		14.0929759185
253PhosphorylationGNPAYKCTICGKAFY
CCCCEEEEECCCCHH		18.3629759185
264PhosphorylationKAFYFLNSVERHQRT
CCHHHHHHHHHHCCC		27.7428555341
265UbiquitinationAFYFLNSVERHQRTH
CHHHHHHHHHHCCCC		7.9322505724
271PhosphorylationSVERHQRTHTGEKPY
HHHHHCCCCCCCCCE		19.7428348404
273PhosphorylationERHQRTHTGEKPYKC
HHHCCCCCCCCCEEC		46.5626270265
276UbiquitinationQRTHTGEKPYKCKQC
CCCCCCCCCEECCCC		55.80-
278PhosphorylationTHTGEKPYKCKQCGK
CCCCCCCEECCCCCC		39.83-
288PhosphorylationKQCGKAFTVSGSCLI
CCCCCEEEEECCEEE		20.7227080861
290PhosphorylationCGKAFTVSGSCLIHE
CCCEEEEECCEEEEE		23.1827080861
292PhosphorylationKAFTVSGSCLIHERT
CEEEEECCEEEEECC		9.7627080861
299PhosphorylationSCLIHERTHTGEKPY
CEEEEECCCCCCCCE		22.3229396449
301PhosphorylationLIHERTHTGEKPYEC
EEEECCCCCCCCEEE		46.5629496963
302UbiquitinationIHERTHTGEKPYECK
EEECCCCCCCCEEEC		33.0722505724
304UbiquitinationERTHTGEKPYECKEC
ECCCCCCCCEEECCC		55.0022505724
309SumoylationGEKPYECKECGKTFR
CCCCEEECCCCCEEE		44.06-
309SumoylationGEKPYECKECGKTFR
CCCCEEECCCCCEEE		44.06-
309UbiquitinationGEKPYECKECGKTFR
CCCCEEECCCCCEEE		44.06-
323PhosphorylationRFSCSFKTHERTHTG
EEEEEEECCCCCCCC		27.27-
329PhosphorylationKTHERTHTGERPYKC
ECCCCCCCCCCCEEC		39.87-
357PhosphorylationRYHGSIHTGERPYEC
EECCEEECCCCCEEH		38.7829214152
365SumoylationGERPYECKQCGKAFS
CCCCEEHHHHHHHHH		36.36-
365SumoylationGERPYECKQCGKAFS
CCCCEEHHHHHHHHH		36.36-
372PhosphorylationKQCGKAFSRLSSLCN
HHHHHHHHHHHHHCC		36.8528555341
376PhosphorylationKAFSRLSSLCNHRST
HHHHHHHHHCCCCCC		41.3528555341
383PhosphorylationSLCNHRSTHTGEKPY
HHCCCCCCCCCCCCC		24.3427251275
385PhosphorylationCNHRSTHTGEKPYEC
CCCCCCCCCCCCCCC		47.3129496963
388UbiquitinationRSTHTGEKPYECKQC
CCCCCCCCCCCCCCH		55.0022505724
403PhosphorylationDQAFSRLSSLHLHER
HHHHHHHHHHHHHHC		29.7328555341
404PhosphorylationQAFSRLSSLHLHERI
HHHHHHHHHHHHHCC		25.1328555341
413PhosphorylationHLHERIHTGEKPYEC
HHHHCCCCCCCCCCC		44.6729496963
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN669_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN669_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN669_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
FBXW8_HUMANFBXW8physical
28514442
ANKS3_HUMANANKS3physical
28514442
CUL7_HUMANCUL7physical
28514442
SESD1_HUMANSESTD1physical
28514442
ANR27_HUMANANKRD27physical
28514442
MTMR4_HUMANMTMR4physical
28514442
TRI41_HUMANTRIM41physical
28514442
TRI39_HUMANTRIM39physical
28514442
KBTB7_HUMANKBTBD7physical
28514442
UBP34_HUMANUSP34physical
28514442
LTBP4_HUMANLTBP4physical
28514442
SMRCD_HUMANSMARCAD1physical
28514442
NEK7_HUMANNEK7physical
28514442
RN187_HUMANRNF187physical
28514442
LRP4_HUMANLRP4physical
28514442
CENPB_HUMANCENPBphysical
28514442
TIF1B_HUMANTRIM28physical
28514442
ANR52_HUMANANKRD52physical
28514442
NEUL4_HUMANNEURL4physical
28514442
GGPPS_HUMANGGPS1physical
28514442
SIR1_HUMANSIRT1physical
28514442
TRBP2_HUMANTARBP2physical
28514442
UBE2O_HUMANUBE2Ophysical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN669_HUMAN

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Related Literatures of Post-Translational Modification

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