| UniProt ID | TNR9_HUMAN | |
|---|---|---|
| UniProt AC | Q07011 | |
| Protein Name | Tumor necrosis factor receptor superfamily member 9 | |
| Gene Name | TNFRSF9 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 255 | |
| Subcellular Localization |
Membrane Single-pass type I membrane protein. |
|
| Protein Description | Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.. | |
| Protein Sequence | MGNSCYNIVATLLLVLNFERTRSLQDPCSNCPAGTFCDNNRNQICSPCPPNSFSSAGGQRTCDICRQCKGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKGCKDCCFGTFNDQKRGICRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPGASSVTPPAPAREPGHSPQIISFFLALTSTALLFLLFFLTLRFSVVKRGRKKLLYIFKQPFMRPVQTTQEEDGCSCRFPEEEEGGCEL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 138 | N-linked_Glycosylation | GICRPWTNCSLDGKS CCCCCCCCCCCCCCE | 14.98 | UniProtKB CARBOHYD | |
| 149 | N-linked_Glycosylation | DGKSVLVNGTKERDV CCCEEEECCCCCCCC | 48.53 | UniProtKB CARBOHYD | |
| 214 | Ubiquitination | TLRFSVVKRGRKKLL HHHHHHHHCCHHHEE | 47.16 | 23000965 | |
| 218 | Ubiquitination | SVVKRGRKKLLYIFK HHHHCCHHHEEEEEC | 51.07 | 23000965 | |
| 219 | Ubiquitination | VVKRGRKKLLYIFKQ HHHCCHHHEEEEECC | 42.22 | 23000965 | |
| 225 | Ubiquitination | KKLLYIFKQPFMRPV HHEEEEECCCCCCCC | 47.72 | 23000965 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TNR9_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TNR9_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TNR9_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| TNR9_HUMAN | TNFRSF9 | physical | 9045669 | |
| TRAF1_HUMAN | TRAF1 | physical | 9464265 | |
| TRAF3_HUMAN | TRAF3 | physical | 9464265 | |
| TRAF2_HUMAN | TRAF2 | physical | 9418902 | |
| LLR1_HUMAN | LRR1 | physical | 11804328 | |
| TNR4_HUMAN | TNFRSF4 | physical | 15941918 | |
| TRAF2_HUMAN | TRAF2 | physical | 23690480 | |
| AT12A_HUMAN | ATP12A | physical | 26186194 | |
| S39A6_HUMAN | SLC39A6 | physical | 26186194 | |
| CERK1_HUMAN | CERK | physical | 26186194 | |
| TNFL9_HUMAN | TNFSF9 | physical | 26186194 | |
| TRAF1_HUMAN | TRAF1 | physical | 9607925 | |
| TRAF2_HUMAN | TRAF2 | physical | 9607925 | |
| CERK1_HUMAN | CERK | physical | 28514442 | |
| TNFL9_HUMAN | TNFSF9 | physical | 28514442 | |
| SNX11_HUMAN | SNX11 | physical | 28514442 | |
| AT12A_HUMAN | ATP12A | physical | 28514442 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| D09984 | Urelumab (USAN/INN) | |||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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