RELL2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RELL2_HUMAN
• UniProt AC: Q8NC24
• Protein Name: RELT-like protein 2
• Gene Name: RELL2
• Organism: Homo sapiens (Human).
• Sequence Length: 303
• Subcellular Localization: Cell membrane ; Single-pass membrane protein .
• Protein Sequence: MSEPQPDLEPPQHGLYMLFLLVLVFFLMGLVGFMICHVLKKKGYRCRTSRGSEPDDAQLQPPEDDDMNEDTVERIVRCIIQNEANAEALKEMLGDSEGEGTVQLSSVDATSSLQDGAPSHHHTVHLGSAAPCLHCSRSKRPPLVRQGRSKEGKSRPRTGETTVFSVGRFRVTHIEKRYGLHEHRDGSPTDRSWGSGGGQDPGGGQGSGGGQPKAGMPAMERLPPERPQPQVLASPPVQNGGLRDSSLTPRALEGNPRASAEPTLRAGGRGPSPGLPTQEANGQPSKPDTSDHQVSLPQGAGSM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
48	Phosphorylation	KKGYRCRTSRGSEPD HCCCCCCCCCCCCCC	26.80	23186163
49	Phosphorylation	KGYRCRTSRGSEPDD CCCCCCCCCCCCCCC	18.45	23186163
52	Phosphorylation	RCRTSRGSEPDDAQL CCCCCCCCCCCCCCC	44.86	23186163
149	Phosphorylation	PLVRQGRSKEGKSRP CCHHCCCCCCCCCCC	41.71	-
158	Phosphorylation	EGKSRPRTGETTVFS CCCCCCCCCCCEEEE	41.89	28555341
187	Phosphorylation	LHEHRDGSPTDRSWG CCCCCCCCCCCCCCC	28.99	28450419
189	Phosphorylation	EHRDGSPTDRSWGSG CCCCCCCCCCCCCCC	45.82	28450419
192	Phosphorylation	DGSPTDRSWGSGGGQ CCCCCCCCCCCCCCC	38.30	28450419
195	Phosphorylation	PTDRSWGSGGGQDPG CCCCCCCCCCCCCCC	28.18	28450419
234	Phosphorylation	PQPQVLASPPVQNGG CCCCEECCCCCCCCC	26.10	28555341

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RELL2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RELL2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RELL2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TRIM9_HUMAN	TRIM9	physical	28514442
OXSR1_HUMAN	OXSR1	physical	28514442
LLR1_HUMAN	LRR1	physical	28514442
STK39_HUMAN	STK39	physical	28514442
TR19L_HUMAN	RELT	physical	28514442
CBPC5_HUMAN	AGBL5	physical	28514442
MCM10_HUMAN	MCM10	physical	28514442
MGST2_HUMAN	MGST2	physical	28514442
HSP7E_HUMAN	HSPA14	physical	28514442
DYH14_HUMAN	DNAH14	physical	28514442
SL9A6_HUMAN	SLC9A6	physical	28514442
ECHB_HUMAN	HADHB	physical	28514442
KIF2C_HUMAN	KIF2C	physical	28514442
CF120_HUMAN	C6orf120	physical	28514442
ECHA_HUMAN	HADHA	physical	28514442
GRIN1_HUMAN	GPRIN1	physical	28514442
RHEB_HUMAN	RHEB	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.