MTND2_ARATH - dbPTM
MTND2_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MTND2_ARATH
UniProt AC Q8GXE2
Protein Name 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2 {ECO:0000255|HAMAP-Rule:MF_03154}
Gene Name ARD2
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 192
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene)..
Protein Sequence MGEAVKDGREEVIQAWYMDDSEEDQRLPHHKDPKEFVSLDKLAELGVLSWRLDADNYETDEDLKKIRESRGYSYMDFCEVCPEKLPNYEVKVKSFFEEHLHTDEEIRYCVAGTGYFDVRDRNEAWIRVLVKKGGMIVLPAGIYHRFTVDSDNYIKAMRLFVGEPVWTPYNRPHDHLPARKEYVDNFMINASA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
57PhosphorylationWRLDADNYETDEDLK
EEECCCCCCCHHHHH
22.2823776212
59PhosphorylationLDADNYETDEDLKKI
ECCCCCCCHHHHHHH
34.0423776212
147PhosphorylationAGIYHRFTVDSDNYI
CCEEEEEEECCCCCE
24.3028295753
150PhosphorylationYHRFTVDSDNYIKAM
EEEEEECCCCCEEEE
24.3428295753
153PhosphorylationFTVDSDNYIKAMRLF
EEECCCCCEEEEEEC
14.5928295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MTND2_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MTND2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MTND2_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GBB_ARATHAGB1physical
21712381
MTND2_ARATHARD1physical
21712381
Y5010_ARATHAT5G50100physical
21952135
MTND4_ARATHARD4physical
21952135
P4H9_ARATHAT4G33910physical
21952135
SODF1_ARATHFSD1physical
21952135
PER42_ARATHPRXR1physical
21952135
RPB7L_ARATHAT4G14520physical
21952135
CYSKM_ARATHOASCphysical
21952135
LECT2_ARATHAT3G15356physical
21952135
XTH4_ARATHXTH4physical
21952135
RBS1A_ARATHRBCS1Aphysical
21952135
RL212_ARATHAT1G57660physical
21952135
FYPP1_ARATHAT1G50370physical
21952135
MYC2_ARATHMYC2physical
21952135
NDB3B_ARATHAT1G14450physical
21952135

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MTND2_ARATH

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Related Literatures of Post-Translational Modification

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