RBS1A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RBS1A_ARATH
• UniProt AC: P10795
• Protein Name: Ribulose bisphosphate carboxylase small chain 1A, chloroplastic
• Gene Name: RBCS-1A
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 180
• Subcellular Localization: Plastid, chloroplast membrane ; Peripheral membrane protein . Plastid, chloroplast stroma .
• Protein Description: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site (By similarity)..
• Protein Sequence: MASSMLSSATMVASPAQATMVAPFNGLKSSAAFPATRKANNDITSITSNGGRVNCMQVWPPIGKKKFETLSYLPDLTDSELAKEVDYLIRNKWIPCVEFELEHGFVYREHGNSPGYYDGRYWTMWKLPLFGCTDSAQVLKEVEECKKEYPNAFIRIIGFDNTRQVQCISFIAYKPPSFTG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
69	Phosphorylation	IGKKKFETLSYLPDL CCCCEEEEECCCCCC	24.92	22092075
71	Phosphorylation	KKKFETLSYLPDLTD CCEEEEECCCCCCCH	31.85	23776212
72	Phosphorylation	KKFETLSYLPDLTDS CEEEEECCCCCCCHH	25.93	23776212
77	Phosphorylation	LSYLPDLTDSELAKE ECCCCCCCHHHHHHH	44.88	30291188
79	Phosphorylation	YLPDLTDSELAKEVD CCCCCCHHHHHHHHH	29.31	30291188
87	Phosphorylation	ELAKEVDYLIRNKWI HHHHHHHHHHHCCCC	14.81	29654922
113	Phosphorylation	VYREHGNSPGYYDGR EEEECCCCCCCCCCC	25.05	23776212
116	Phosphorylation	EHGNSPGYYDGRYWT ECCCCCCCCCCCCEE	11.19	23776212
117	Phosphorylation	HGNSPGYYDGRYWTM CCCCCCCCCCCCEEE	20.17	23776212
126	Acetylation	GRYWTMWKLPLFGCT CCCEEEEEEEECCCC	29.42	21311031
133	Phosphorylation	KLPLFGCTDSAQVLK EEEECCCCCHHHHHH	33.11	30291188
135	Phosphorylation	PLFGCTDSAQVLKEV EECCCCCHHHHHHHH	11.49	30291188
162	Phosphorylation	RIIGFDNTRQVQCIS EEEECCCCCEEEEEE	25.07	30291188
177	Phosphorylation	FIAYKPPSFTG---- EEEECCCCCCC----	43.92	19376835
179	Phosphorylation	AYKPPSFTG------ EECCCCCCC------	46.44	29654922

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RBS1A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RBS1A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RBS1A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MD37C_ARATH	HSP70	physical	20028838
SUMO3_ARATH	SUMO3	physical	20855607
SUMO1_ARATH	SUMO1	physical	20855607

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-79; SER-113 AND SER-177,AND MASS SPECTROMETRY.
PubMed: 19376835