dbPTM

CYSKM_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CYSKM_ARATH
UniProt AC	Q43725
Protein Name	Cysteine synthase, mitochondrial
Gene Name	OASC
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	430
Subcellular Localization	Mitochondrion .
Protein Description	Acts as a cysteine synthase. Plays a role in the sulfide detoxification in mitochondria..
Protein Sequence	MVAMIMASRFNREAKLASQILSTLLGNRSCYTSMAATSSSALLLNPLTSSSSSSTLRRFRCSPEISSLSFSSASDFSLAMKRQSRSFADGSERDPSVVCEAVKRETGPDGLNIADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGERYLSTPLFQSIREEVEKMQPEV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
154	N6-(pyridoxal phosphate)lysine	MEPCCSVKDRIGYSM CCCCCCCCHHCCCEE	25.62	-
154	Other	MEPCCSVKDRIGYSM CCCCCCCCHHCCCEE	25.62	-
293	Phosphorylation	AGIGTGGTITGVGRF EECCCCCCHHHHHHH	19.40	29654922
355	Phosphorylation	MDEVIAISSEEAIET HHHHHHHCHHHHHHH	23.75	24894044
405	Phosphorylation	LIAVVFPSFGERYLS EEEEECCCCCHHHCC	34.12	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CYSKM_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CYSKM_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CYSKM_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
SAT5_ARATH	SERAT1;1	physical	10940562
CYSKM_ARATH	OASC	physical	10940562

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CYSKM_ARATH

Related Literatures of Post-Translational Modification