FXL16_MOUSE - dbPTM
FXL16_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FXL16_MOUSE
UniProt AC A2RT62
Protein Name F-box/LRR-repeat protein 16
Gene Name Fbxl16
Organism Mus musculus (Mouse).
Sequence Length 479
Subcellular Localization
Protein Description Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex..
Protein Sequence MSSPGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPAAKNRPCQPPPPPTLPPPSLATPLSRVALAGGPCPPASGPASGPVSGPPVERPPLATDEKILNGLFWYFSACEKCILAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYSLSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTSLSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLAMRNLRLLSLAGCPLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCLVIE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
47S-palmitoylationPAAKNRPCQPPPPPT
CCHHCCCCCCCCCCC
9.5328680068
74S-palmitoylationVALAGGPCPPASGPA
HHHCCCCCCCCCCCC
7.7328680068
92MethylationVSGPPVERPPLATDE
CCCCCCCCCCCCCCH
38.0724129315
155UbiquitinationNVLPGGEKEFVNLQG
HCCCCCCEEEECCHH
60.7822790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FXL16_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FXL16_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FXL16_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SKP1_MOUSESkp1aphysical
24390425
2AAA_MOUSEPpp2r1aphysical
24390425
2AAA_HUMANPPP2R1Aphysical
24390425
PP2AB_HUMANPPP2CBphysical
24390425
2ABA_HUMANPPP2R2Aphysical
24390425
SKP1_HUMANSKP1physical
24390425
K1C10_HUMANKRT10physical
24390425
C1QBP_HUMANC1QBPphysical
24390425
DDX1_HUMANDDX1physical
24390425
RBBP5_HUMANRBBP5physical
24390425
RL35_HUMANRPL35physical
24390425
RL15_HUMANRPL15physical
24390425
CLH1_HUMANCLTCphysical
24390425
DHX30_HUMANDHX30physical
24390425
ANM1_HUMANPRMT1physical
24390425
RS9_HUMANRPS9physical
24390425
K22E_HUMANKRT2physical
24390425
RS29_HUMANRPS29physical
24390425
XRCC5_HUMANXRCC5physical
24390425
SET_HUMANSETphysical
24390425
PP2AB_MOUSEPpp2cbphysical
24390425
2ABA_MOUSEPpp2r2aphysical
24390425

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FXL16_MOUSE

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Related Literatures of Post-Translational Modification

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