UniProt ID | FXL16_MOUSE | |
---|---|---|
UniProt AC | A2RT62 | |
Protein Name | F-box/LRR-repeat protein 16 | |
Gene Name | Fbxl16 | |
Organism | Mus musculus (Mouse). | |
Sequence Length | 479 | |
Subcellular Localization | ||
Protein Description | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.. | |
Protein Sequence | MSSPGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPAAKNRPCQPPPPPTLPPPSLATPLSRVALAGGPCPPASGPASGPVSGPPVERPPLATDEKILNGLFWYFSACEKCILAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYSLSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTSLSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLAMRNLRLLSLAGCPLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCLVIE | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
47 | S-palmitoylation | PAAKNRPCQPPPPPT CCHHCCCCCCCCCCC | 9.53 | 28680068 | |
74 | S-palmitoylation | VALAGGPCPPASGPA HHHCCCCCCCCCCCC | 7.73 | 28680068 | |
92 | Methylation | VSGPPVERPPLATDE CCCCCCCCCCCCCCH | 38.07 | 24129315 | |
155 | Ubiquitination | NVLPGGEKEFVNLQG HCCCCCCEEEECCHH | 60.78 | 22790023 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FXL16_MOUSE !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FXL16_MOUSE !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FXL16_MOUSE !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
SKP1_MOUSE | Skp1a | physical | 24390425 | |
2AAA_MOUSE | Ppp2r1a | physical | 24390425 | |
2AAA_HUMAN | PPP2R1A | physical | 24390425 | |
PP2AB_HUMAN | PPP2CB | physical | 24390425 | |
2ABA_HUMAN | PPP2R2A | physical | 24390425 | |
SKP1_HUMAN | SKP1 | physical | 24390425 | |
K1C10_HUMAN | KRT10 | physical | 24390425 | |
C1QBP_HUMAN | C1QBP | physical | 24390425 | |
DDX1_HUMAN | DDX1 | physical | 24390425 | |
RBBP5_HUMAN | RBBP5 | physical | 24390425 | |
RL35_HUMAN | RPL35 | physical | 24390425 | |
RL15_HUMAN | RPL15 | physical | 24390425 | |
CLH1_HUMAN | CLTC | physical | 24390425 | |
DHX30_HUMAN | DHX30 | physical | 24390425 | |
ANM1_HUMAN | PRMT1 | physical | 24390425 | |
RS9_HUMAN | RPS9 | physical | 24390425 | |
K22E_HUMAN | KRT2 | physical | 24390425 | |
RS29_HUMAN | RPS29 | physical | 24390425 | |
XRCC5_HUMAN | XRCC5 | physical | 24390425 | |
SET_HUMAN | SET | physical | 24390425 | |
PP2AB_MOUSE | Ppp2cb | physical | 24390425 | |
2ABA_MOUSE | Ppp2r2a | physical | 24390425 |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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