CC107_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC107_HUMAN
• UniProt AC: Q8WV48
• Protein Name: Coiled-coil domain-containing protein 107
• Gene Name: CCDC107
• Organism: Homo sapiens (Human).
• Sequence Length: 283
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MAGAVSLLGVVGLLLVSALSGVLGDRANPDLRAHPGNAAHPGSGATEPRRRPPLKDQRERTRAGSLPLGALYTAAVAAFVLYKCLQGKDETAVLHEEASKQQPLQSEQQLAQLTQQLAQTEQHLNNLMAQLDPLFERVTTLAGAQQELLNMKLWTIHELLQDSKPDKDMEASEPGEGSGGESAGGGDKVSETGTFLISPHTEASRPLPEDFCLKEDEEEIGDSQAWEEPTNWSTETWNLATSWEVGRGLRRRCSQAVAKGPSHSLGWEGGTTAEGRLKQSLFS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
88	Ubiquitination	LYKCLQGKDETAVLH HHHHHCCCCCHHHHC	39.16	29967540
139	Phosphorylation	DPLFERVTTLAGAQQ HHHHHHHHHHHHHHH	23.47	-
140	Phosphorylation	PLFERVTTLAGAQQE HHHHHHHHHHHHHHH	16.26	-
254	Phosphorylation	RGLRRRCSQAVAKGP HHHHHHHHHHHHCCC	21.25	24719451
283	Phosphorylation	RLKQSLFS------- HHHHHHCC-------	44.60	21712546

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC107_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC107_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC107_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
IMA1_HUMAN	KPNA2	physical	21988832
TRPM4_HUMAN	TRPM4	physical	28514442
GCC2_HUMAN	GCC2	physical	28514442
STX18_HUMAN	STX18	physical	28514442
SEC20_HUMAN	BNIP1	physical	28514442
FBX11_HUMAN	FBXO11	physical	28514442
SL9A1_HUMAN	SLC9A1	physical	28514442
TM214_HUMAN	TMEM214	physical	28514442
GOGA5_HUMAN	GOLGA5	physical	28514442
CENPH_HUMAN	CENPH	physical	28514442
ALG8_HUMAN	ALG8	physical	28514442
PIGA_HUMAN	PIGA	physical	28514442
STX5_HUMAN	STX5	physical	28514442
PLD2_HUMAN	PLD2	physical	28514442
CNEP1_HUMAN	CTDNEP1	physical	28514442
CXCR4_HUMAN	CXCR4	physical	28514442
COPG1_HUMAN	COPG1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.