B4GT3_HUMAN - dbPTM
B4GT3_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID B4GT3_HUMAN
UniProt AC O60512
Protein Name Beta-1,4-galactosyltransferase 3
Gene Name B4GALT3
Organism Homo sapiens (Human).
Sequence Length 393
Subcellular Localization Golgi apparatus, Golgi stack membrane
Single-pass type II membrane protein. Trans cisternae of Golgi stack.
Protein Description Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids..
Protein Sequence MLRRLLERPCTLALLVGSQLAVMMYLSLGGFRSLSALFGRDQGPTFDYSHPRDVYSNLSHLPGAPGGPPAPQGLPYCPERSPLLVGPVSVSFSPVPSLAEIVERNPRVEPGGRYRPAGCEPRSRTAIIVPHRAREHHLRLLLYHLHPFLQRQQLAYGIYVIHQAGNGTFNRAKLLNVGVREALRDEEWDCLFLHDVDLLPENDHNLYVCDPRGPRHVAVAMNKFGYSLPYPQYFGGVSALTPDQYLKMNGFPNEYWGWGGEDDDIATRVRLAGMKISRPPTSVGHYKMVKHRGDKGNEENPHRFDLLVRTQNSWTQDGMNSLTYQLLARELGPLYTNITADIGTDPRGPRAPSGPRYPPGSSQAFRQEMLQRRPPARPGPLSTANHTALRGSH
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
45O-linked_GlycosylationFGRDQGPTFDYSHPR
HCCCCCCCCCCCCCH		35.6455825111
49O-linked_GlycosylationQGPTFDYSHPRDVYS
CCCCCCCCCCHHHHH		28.9455825117
57N-linked_GlycosylationHPRDVYSNLSHLPGA
CCHHHHHCHHCCCCC		28.07UniProtKB CARBOHYD
89PhosphorylationPLLVGPVSVSFSPVP
CEEEECEEEECCCCC		18.3822210691
91O-linked_GlycosylationLVGPVSVSFSPVPSL
EEECEEEECCCCCCH		16.70OGP
91PhosphorylationLVGPVSVSFSPVPSL
EEECEEEECCCCCCH		16.7022210691
93O-linked_GlycosylationGPVSVSFSPVPSLAE
ECEEEECCCCCCHHH		19.92OGP
93PhosphorylationGPVSVSFSPVPSLAE
ECEEEECCCCCCHHH		19.9222210691
97O-linked_GlycosylationVSFSPVPSLAEIVER
EECCCCCCHHHHHHH		40.21OGP
125PhosphorylationGCEPRSRTAIIVPHR
CCCCCCCCEEEECCC		24.37-
143PhosphorylationHHLRLLLYHLHPFLQ
HHHHHHHHHHHHHHH		11.42-
166N-linked_GlycosylationYVIHQAGNGTFNRAK
EEEEECCCCCCCHHH		49.71UniProtKB CARBOHYD
173UbiquitinationNGTFNRAKLLNVGVR
CCCCCHHHHCCHHHH		50.71-
207PhosphorylationPENDHNLYVCDPRGP
CCCCCCEEEECCCCH		12.35-
227O-linked_GlycosylationAMNKFGYSLPYPQYF
EEHHCCCCCCCCCCC		24.21OGP
275UbiquitinationRVRLAGMKISRPPTS
HHHHCCCEECCCCCC		36.29-
287UbiquitinationPTSVGHYKMVKHRGD
CCCCCCEEECCCCCC		31.38-
310PhosphorylationRFDLLVRTQNSWTQD
CCCEEEEECCCCCCC		25.3224043423
313PhosphorylationLLVRTQNSWTQDGMN
EEEEECCCCCCCCHH		22.9824043423
315PhosphorylationVRTQNSWTQDGMNSL
EEECCCCCCCCHHHH		19.3224043423
315O-linked_GlycosylationVRTQNSWTQDGMNSL
EEECCCCCCCCHHHH		19.32OGP
321PhosphorylationWTQDGMNSLTYQLLA
CCCCCHHHHHHHHHH		17.1324043423
323PhosphorylationQDGMNSLTYQLLARE
CCCHHHHHHHHHHHH		14.7224043423
324PhosphorylationDGMNSLTYQLLAREL
CCHHHHHHHHHHHHH		11.4924043423
337N-linked_GlycosylationELGPLYTNITADIGT
HHHHCCCEEEEECCC		18.96UniProtKB CARBOHYD
361PhosphorylationGPRYPPGSSQAFRQE
CCCCCCCCCHHHHHH		25.6727282143
362PhosphorylationPRYPPGSSQAFRQEM
CCCCCCCCHHHHHHH		31.2927282143
385N-linked_GlycosylationPGPLSTANHTALRGS
CCCCCHHCCCCCCCC		32.88UniProtKB CARBOHYD
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of B4GT3_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of B4GT3_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of B4GT3_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ATPB_HUMANATP5Bphysical
26186194
GHITM_HUMANGHITMphysical
26186194
XYLT2_HUMANXYLT2physical
26186194
PMGT1_HUMANPOMGNT1physical
26186194
ZDH17_HUMANZDHHC17physical
26186194
AT5F1_HUMANATP5F1physical
26186194
PON2_HUMANPON2physical
26186194
AT5G1_HUMANATP5G1physical
26186194
REEP4_HUMANREEP4physical
26186194
GPHRA_HUMANGPR89Bphysical
26186194
GPHRB_HUMANGPR89Bphysical
26186194
UBE4A_HUMANUBE4Aphysical
26186194
LMF1_HUMANLMF1physical
26186194
ASPH2_HUMANASPHD2physical
26186194
GOGA5_HUMANGOLGA5physical
26186194
FA8A1_HUMANFAM8A1physical
26186194
T120A_HUMANTMEM120Aphysical
26186194
TM205_HUMANTMEM205physical
26186194
AN32A_HUMANANP32Aphysical
26344197
UBE4A_HUMANUBE4Aphysical
28514442
AT5G1_HUMANATP5G1physical
28514442
T120A_HUMANTMEM120Aphysical
28514442
XYLT2_HUMANXYLT2physical
28514442
S19A2_HUMANSLC19A2physical
28514442
ASPH2_HUMANASPHD2physical
28514442
ATPB_HUMANATP5Bphysical
28514442
GOGA5_HUMANGOLGA5physical
28514442
REEP4_HUMANREEP4physical
28514442
AT5F1_HUMANATP5F1physical
28514442
GPHRA_HUMANGPR89Bphysical
28514442
GPHRB_HUMANGPR89Bphysical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of B4GT3_HUMAN

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Related Literatures of Post-Translational Modification

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