ZN396_HUMAN - dbPTM
ZN396_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN396_HUMAN
UniProt AC Q96N95
Protein Name Zinc finger protein 396
Gene Name ZNF396
Organism Homo sapiens (Human).
Sequence Length 335
Subcellular Localization Isoform 1: Nucleus.
Isoform 2: Nucleus. Cytoplasm.
Protein Description Isoform 1 and isoform 2 act as DNA-dependent transcriptional repressors..
Protein Sequence MSAKLGKSSSLLTQTSEECNGILTEKMEEEEQTCDPDSSLHWSSSYSPETFRQQFRQFGYQDSPGPHEALSRLWELCHLWLRPEVHTKEQILELLVLEQFLAILPKELQAWVQKHHPENGEETVTMLEDVERELDGPKQIFFGRRKDMIAEKLAPSEITEELPSSQLMPVKKQLQGASWELQSLRPHDEDIKTTNVKSASRQKTSLGIELHCNVSNILHMNGSQSSTYRGTYEQDGRFEKRQGNPSWKKQQKCDECGKIFSQSSALILHQRIHSGKKPYACDECAKAFSRSAILIQHRRTHTGEKPYKCHDCGKAFSQSSNLFRHRKRHIRKKVP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
8PhosphorylationMSAKLGKSSSLLTQT
CCCCCCCCCHHHHHC		24.3025954137
10PhosphorylationAKLGKSSSLLTQTSE
CCCCCCCHHHHHCHH		34.1925954137
24PhosphorylationEECNGILTEKMEEEE
HHHHCCHHHHHHHHH		31.4725954137
33PhosphorylationKMEEEEQTCDPDSSL
HHHHHHCCCCCCCCC		23.3528787133
39PhosphorylationQTCDPDSSLHWSSSY
CCCCCCCCCCCCCCC		31.4728787133
178PhosphorylationKKQLQGASWELQSLR
HHHHCCCCEEHHHCC		28.1029978859
183PhosphorylationGASWELQSLRPHDED
CCCEEHHHCCCCCCC		38.6829978859
231PhosphorylationQSSTYRGTYEQDGRF
CCCCCCCCCEECCCC		18.1927251275
300PhosphorylationILIQHRRTHTGEKPY
HHEECCCCCCCCCCE		24.6030631047
302PhosphorylationIQHRRTHTGEKPYKC
EECCCCCCCCCCEEC		46.5630631047
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN396_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN396_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN396_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ZSCA1_HUMANZSCAN1physical
20211142
ZKSC3_HUMANZKSCAN3physical
26186194
ZKSC4_HUMANZKSCAN4physical
26186194
ZNF24_HUMANZNF24physical
26186194
PGBD1_HUMANPGBD1physical
26186194
ZKSC8_HUMANZKSCAN8physical
26186194
SCND3_HUMANZBED9physical
26186194
ZN174_HUMANZNF174physical
26186194
ZN446_HUMANZNF446physical
26186194
ZN445_HUMANZNF445physical
26186194
ZSC20_HUMANZSCAN20physical
26186194
ZSC18_HUMANZSCAN18physical
26186194
SCND1_HUMANSCAND1physical
26186194
ZSC18_HUMANZSCAN18physical
28514442
ZN174_HUMANZNF174physical
28514442
ZKSC3_HUMANZKSCAN3physical
28514442
SCND3_HUMANZBED9physical
28514442
PGBD1_HUMANPGBD1physical
28514442
ZNF24_HUMANZNF24physical
28514442
ZKSC4_HUMANZKSCAN4physical
28514442
ZSC20_HUMANZSCAN20physical
28514442
ZKSC8_HUMANZKSCAN8physical
28514442
ZN446_HUMANZNF446physical
28514442
SCND1_HUMANSCAND1physical
28514442
ZN445_HUMANZNF445physical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN396_HUMAN

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Related Literatures of Post-Translational Modification

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