ZSCA1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZSCA1_HUMAN
• UniProt AC: Q8NBB4
• Protein Name: Zinc finger and SCAN domain-containing protein 1
• Gene Name: ZSCAN1
• Organism: Homo sapiens (Human).
• Sequence Length: 408
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MLPRPKAPASPRRPQTPTPSEQDADPGPASPRDTEAQRLRFRQFQYHVASGPHLALGQLWTLCRQWLRPEARSKEQMLELLVLEQFLGALPSKMRTWVQSQGPRSCREAASLVEDLTQMCQQEVLVSLDSVEPQDWSFGEEEDGKSPRSQKEPSQASELILDAVAAAPALPEESEWLETTQLQQSLHTRAEAEAPRAPGLLGSRARLPLKPSIWDEPEDLLAGPSSDLRAEGTVISSPKGPSAQRISPRRRNRNTDQSGRHQPSLKHTKGGTQEAVAGISVVPRGPRGGRPFQCADCGMVFTWVTHFIEHQKTHREEGPFPCPECGKVFLHNSVLTEHGKIHLLEPPRKKAPRSKGPRESVPPRDGAQGPVAPRSPKRPFQCSVCGKAFPWMVHLIDHQKLHTAHGHM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	Phosphorylation	DADPGPASPRDTEAQ CCCCCCCCCCCHHHH	24.49	-
92	Phosphorylation	QFLGALPSKMRTWVQ HHHCCCCHHHHHHHH	39.68	24719451
96	Phosphorylation	ALPSKMRTWVQSQGP CCCHHHHHHHHHCCC	26.87	23684312
100	Phosphorylation	KMRTWVQSQGPRSCR HHHHHHHHCCCHHHH	27.73	23684312
203	Phosphorylation	RAPGLLGSRARLPLK CCCCCCCCCCCCCCC	23.80	-
233	Phosphorylation	SDLRAEGTVISSPKG CCCCEECEEEECCCC	13.23	29396449
236	Phosphorylation	RAEGTVISSPKGPSA CEECEEEECCCCCCC	35.93	29396449
237	Phosphorylation	AEGTVISSPKGPSAQ EECEEEECCCCCCCC	21.36	22115753
242	Phosphorylation	ISSPKGPSAQRISPR EECCCCCCCCCCCCC	45.78	22115753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZSCA1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZSCA1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZSCA1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ZSCA1_HUMAN	ZSCAN1	physical	20211142
A4_HUMAN	APP	physical	21832049
ZNF24_HUMAN	ZNF24	physical	26186194
ZSC25_HUMAN	ZSCAN25	physical	26186194
GOGA3_HUMAN	GOLGA3	physical	26186194
ZN174_HUMAN	ZNF174	physical	26186194
ZN496_HUMAN	ZNF496	physical	26186194
ZSC18_HUMAN	ZSCAN18	physical	26186194
P20D2_HUMAN	PM20D2	physical	26186194
MZF1_HUMAN	MZF1	physical	26186194
PGBD1_HUMAN	PGBD1	physical	26186194
ZN213_HUMAN	ZNF213	physical	26186194
ZSC18_HUMAN	ZSCAN18	physical	28514442
ZN174_HUMAN	ZNF174	physical	28514442
MZF1_HUMAN	MZF1	physical	28514442
ZNF24_HUMAN	ZNF24	physical	28514442
PGBD1_HUMAN	PGBD1	physical	28514442
ZN213_HUMAN	ZNF213	physical	28514442
ZN496_HUMAN	ZNF496	physical	28514442
ZSC25_HUMAN	ZSCAN25	physical	28514442
GOGA3_HUMAN	GOLGA3	physical	28514442
ANM8_HUMAN	PRMT8	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.