SCND3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SCND3_HUMAN
• UniProt AC: Q6R2W3
• Protein Name: SCAN domain-containing protein 3
• Gene Name: ZBED9
• Organism: Homo sapiens (Human).
• Sequence Length: 1325
• Protein Sequence: MEAVSRVFPALAGQAPEEQGEIIKVKVKEEDHTWDQESALRRNLSYTRELSRQRFRQFCYQETPGPREALSQLRELCRQWLNPEIHTKEQILELLVLEQFLTILPEELQSWVREHNPESGEEVVTLLEDLERELDEPRQQVSQGTYGQEVSMEEMIPLDSAKESLGTQLQSMEDRMECESPEPHPLQDNGSFLWFSMMSQSMGGDNLSSLDTNEAEIEPENMREKFFRSLARLLENKSNNTKIFSKAKYCQLIKEVKEAKAKAKKESVDYRRLARFDVILVQGNEKLIEAVNGETDKIRYYLHSEDLFDILHNTHLSIGHGGRTRMEKELQAKYKNITKEVIMLYLTLCKPCQQKNSKLKKVLTSKSIKEVSSRCQVDLIDMQLNPDGEYRFILHYQDLCTKLTFLRSLKSKRPTEVAHALLDIFTIIGAPSVLQSDNGREFSSQVVSELSNIWPELKIVHGKSQTCQSQSSAEQTEDIRKRIFSWMQTNNSSHWTEFLWFIQMSQNQPYHRSMQQTPCESAFSSEAKLGLSHSQLTEELVASLHTENELDQADKELENTLRAQYEENIETGTDSSDIEENLSVTPKVAEKSPPESRLRFLSCVVCEKECTGVNSCISCDGNIHAICGVPSQHGTEGCGRQITCSLCYETSTMKRKHDEIQRSLPVKPSKMLKPSGTPFSPDKVGDWMAKQASLDFFVKKRHAFSEHSSSNKRNVNNRSYPEEGKTKRVHASFTRKYDPSYIEFGFVAVIDGEVLKPQCIICGDVLANEAMKPSKLKRHLYSKHKEISSQPKEFFERKSSELKSQPKQVFNVSHINISALRASYKVALPVAKSKTPYTIAETLVKDCIKEVCLEMLGESAAKKVAQVPLSNDTIARRIQELANDMEDQLIEQIKLAKYFSLQLDECRDIANMIILLVYVRFEHDDDIKEEFFFSASLPTNTTSSELYEAVKNYIVNKCGLEFKFCVGVCSDGAASMTGKHSEVVTQIKELAPECKTTHCFIHRESLAMKKISAELNSVLNDIVKIVNYIKSNSLNSRLFSLLCDNMEADHKQLLLHAEIRWLSRGKVLSRMFEIRNELLVFLQGKKPMWSQLFKDVNWTARLAYLSDIFSIFNDLNASMQGKNATYFSMADKVEGQKQKLEAWKNRISTDCYDMFHNLTTIINEVGNDLDIAHLRKVISEHLTNLLECFEFYFPSKEDPRIGNLWIQNPFLSSKDNLNLTVTLQDKLLKLATDEGLKISFENTASLPSFWIKAKNDYPELAEIALKLLLLFPSTYLCETGFSTLSVIKTKHRNSLNIHYPLRVALSSIQPRLDKLTSKKQAHLSH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
71	Phosphorylation	PGPREALSQLRELCR CCHHHHHHHHHHHHH	33.93	24719451
171	Phosphorylation	SLGTQLQSMEDRMEC HHHHHHHHHHHHHCC	32.50	-
245	Phosphorylation	SNNTKIFSKAKYCQL CCCCCCCHHHHHHHH	34.87	24719451
249	Phosphorylation	KIFSKAKYCQLIKEV CCCHHHHHHHHHHHH	7.12	-
262	Acetylation	EVKEAKAKAKKESVD HHHHHHHHHHHHCCC	61.09	12654543
264	Acetylation	KEAKAKAKKESVDYR HHHHHHHHHHCCCHH	57.26	18584505
265	Acetylation	EAKAKAKKESVDYRR HHHHHHHHHCCCHHH	61.14	12654551
300	Phosphorylation	GETDKIRYYLHSEDL CCCCCEEEEECCHHH	17.53	-
364	Phosphorylation	SKLKKVLTSKSIKEV CHHHHHHCCCCHHHH	36.78	29449344
365	Phosphorylation	KLKKVLTSKSIKEVS HHHHHHCCCCHHHHH	21.90	29449344
367	Phosphorylation	KKVLTSKSIKEVSSR HHHHCCCCHHHHHHH	38.36	29449344
573	Phosphorylation	EENIETGTDSSDIEE HHHHCCCCCCHHHHH	39.88	25921289
575	Phosphorylation	NIETGTDSSDIEENL HHCCCCCCHHHHHHH	29.73	25921289
576	Phosphorylation	IETGTDSSDIEENLS HCCCCCCHHHHHHHC	45.47	25921289
583	Phosphorylation	SDIEENLSVTPKVAE HHHHHHHCCCHHHHH	35.21	24719451
651	Phosphorylation	CSLCYETSTMKRKHD EEHHHCCCCCCCCCH	17.98	-
663	Phosphorylation	KHDEIQRSLPVKPSK CCHHHHHCCCCCHHH	22.20	29396449
782	Phosphorylation	KLKRHLYSKHKEISS HHHHHHHHHHHHHHH	34.34	24719451
813	Phosphorylation	PKQVFNVSHINISAL CCEEEECHHHCHHHH	21.54	27251275
818	Phosphorylation	NVSHINISALRASYK ECHHHCHHHHHHHEE	19.43	27251275
944	O-linked_Glycosylation	LPTNTTSSELYEAVK CCCCCCCHHHHHHHH	29.54	29351928
953	Phosphorylation	LYEAVKNYIVNKCGL HHHHHHHHHHHCCCC	10.67	28258704
981	Phosphorylation	ASMTGKHSEVVTQIK HHHCCCHHHHHHHHH	35.26	28258704
1031	Phosphorylation	KIVNYIKSNSLNSRL HHHHHHHCCCCCHHH	23.30	28634120
1033	Phosphorylation	VNYIKSNSLNSRLFS HHHHHCCCCCHHHHH	35.70	26546556
1220	Phosphorylation	SKDNLNLTVTLQDKL CCCCEEEEEEHHHHH	15.46	30622161
1222	Phosphorylation	DNLNLTVTLQDKLLK CCEEEEEEHHHHHHH	17.29	30622161
1232	Phosphorylation	DKLLKLATDEGLKIS HHHHHHHCCCCCEEE	45.05	-
1299	Phosphorylation	RNSLNIHYPLRVALS CCCCCCCCCHHHHHH	10.52	30622161
1316	Phosphorylation	QPRLDKLTSKKQAHL HHHHHHHCHHHHHHC	44.21	-
1317	Phosphorylation	PRLDKLTSKKQAHLS HHHHHHCHHHHHHCC	48.57	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SCND3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SCND3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SCND3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SCND3_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.