TPR3_ARATH - dbPTM
TPR3_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TPR3_ARATH
UniProt AC Q84JM4
Protein Name Topless-related protein 3
Gene Name TPR3
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 1108
Subcellular Localization Nucleus.
Protein Description Transcriptional corepressor. Negative regulator of jasmonate responses (By similarity)..
Protein Sequence MSSLSRELVFLILQFLEEEKFKESVHRLEKESGFFFNTKYFDEKVLAGEWDDVETYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDRQEKAKAVEILVQDLRVFSTFNEELYKEITQLLTLQNFRENEQLSKYGDTKTARGIMLGELKKLIEANPLFRDKLMFPTLRSSRLRTLINQSLNWQHQLCKNPRPNPDIKTLFTDHTCTLPNGPLAPSAVNQPVTTLTKPAAYPSLGPHVPFPPGPAAANAGALASWMAAASGASAVQAAVVTPALMPQPQNQMSILKRPRTPPATPGIVDYQNPDHELMKRLRPAPSVEEVTYPAPRQQAPWSLEDLPTKAALALHQGSTVTSMEFYPMQNTLLLVGSATGEITLWELAARERLVSRPFKIWDMSNCSHQFQALIAKETPISVTRVAWSPDGNFIGVAFTKHLIQLYAFSGPNDLRQHTEIDAHVGAVNDLAFANPNRQLCVITCGDDKLIKVWDVSGRKHFTFEGHDAPVYSICPHYKENIQFIFSTAIDGKIKAWLYDNLGSRVDYDAPGKWCTRMLYSADGTRLFSCGTSKDGDSFLVEWNESEGSIKRTYKEFQKKLAGVVQFDTSKNHFLAVGEDGQIKFWDMNNINVLTSTDAEGGLPALPHLRFNKDGNLLAVTTADNGFKILANPAGFRSLRAMETPASETMRTPVDFKAVPGAPVASVNCKVERGSPVRHSQMLNGVDPSKSRIDDSTDKPKSWQLAEILDPSQCFQATLPDTAGSSTKVVQLLYTNSGAGILALGSNGIQRLWKWVPNEQNPSGKATATVVPQHWQPNSGLLMTNDVSGVNLENAAPCIALSKNDSYVMSAAGGKVSLFNMMTFKVMTTFMPPPPASTFLAFHPQDNNVIAIGMEDSTIHIYNVRVDEVKSKLKGHQKRITGLAFSTALNILVSSGADAQICFWSIDTWEKRKSVAIQMPAGKAANGDTRVQFHVDQLRILVVHETQLAVFDASKMECIRQWIPQDSLSAPISSAVYACNSQLIYTTFRDGNIGVFDADSLRLRCRISPSAYLPQGNQGLSPLVVAAHPQDPNQFAVGLNDGSVKMMEPTEGEGKWGMIPPSEAINSPSTTSNQTPEQLQR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
214PhosphorylationPNGPLAPSAVNQPVT
CCCCCCCCCCCCCCC
38.96-
288PhosphorylationSILKRPRTPPATPGI
CHHCCCCCCCCCCCC
35.9930291188
292PhosphorylationRPRTPPATPGIVDYQ
CCCCCCCCCCCCCCC
28.0224601666
314PhosphorylationKRLRPAPSVEEVTYP
HHHCCCCCCEECCCC
44.2430291188
535PhosphorylationNLGSRVDYDAPGKWC
CCCCCCCCCCCCCCC
15.9122440515
543PhosphorylationDAPGKWCTRMLYSAD
CCCCCCCCEEEEECC
20.2822440515
702PhosphorylationNCKVERGSPVRHSQM
ECEEECCCCCCHHHE
26.8323776212
723PhosphorylationSKSRIDDSTDKPKSW
CCCCCCCCCCCCCCC
34.4625561503
724PhosphorylationKSRIDDSTDKPKSWQ
CCCCCCCCCCCCCCH
55.8525561503
1089PhosphorylationKWGMIPPSEAINSPS
CCEECCCHHHCCCCC
34.0130407730
1094PhosphorylationPPSEAINSPSTTSNQ
CCHHHCCCCCCCCCC
17.7030407730
1096PhosphorylationSEAINSPSTTSNQTP
HHHCCCCCCCCCCCH
44.1030407730
1097PhosphorylationEAINSPSTTSNQTPE
HHCCCCCCCCCCCHH
37.3130407730
1098PhosphorylationAINSPSTTSNQTPEQ
HCCCCCCCCCCCHHH
29.9830407730
1099PhosphorylationINSPSTTSNQTPEQL
CCCCCCCCCCCHHHH
27.3330407730
1102PhosphorylationPSTTSNQTPEQLQR-
CCCCCCCCHHHHCC-
32.8030407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TPR3_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TPR3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TPR3_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
LBD41_ARATHLBD41physical
22065421
LBD37_ARATHLBD37physical
22065421
RVE7_ARATHEPR1physical
22065421
RAVL1_ARATHTEM1physical
22065421
HSFB1_ARATHHSF4physical
22065421
ERF82_ARATHERF3physical
22065421
ERF78_ARATHERF4physical
22065421
ERF83_ARATHERF7physical
22065421
ERF79_ARATHERF8physical
22065421
ZAT10_ARATHSTZphysical
22065421
MYB32_ARATHMYB32physical
22065421
MYB44_ARATHMYBR1physical
22065421
TI11A_ARATHJAZ5physical
22065421
TI11B_ARATHJAZ6physical
22065421
IAA2_ARATHIAA2physical
22065421
IAA17_ARATHAXR3physical
22065421
ARFB_ARATHARF2physical
22065421
ARFI_ARATHARF9physical
22065421
RAP27_ARATHRAP2.7physical
22065421
TOE2_ARATHTOE2physical
22065421
BEH4_ARATHBEH4physical
22065421
EMF1_ARATHEMF1physical
22065421
ARI1_ARATHARI1physical
22065421
IAA10_ARATHIAA10physical
22065421
ARFQ_ARATHARF17physical
22065421
IAA1_ARATHIAA1physical
22065421
IAA11_ARATHIAA11physical
22065421
BZIP9_ARATHBZIP9physical
22065421
RAV1_ARATHRAV1physical
22065421
SPL1_ARATHSPL1physical
22065421
AP2_ARATHAP2physical
22065421
IAA19_ARATHIAA19physical
22065421
HFB2B_ARATHAT-HSFB2Bphysical
22065421
RAVL3_ARATHAT1G51120physical
22065421
TCP4_ARATHTCP4physical
22065421
SOC1_ARATHAGL20physical
22065421
IAA13_ARATHIAA13physical
22065421
TCP3_ARATHTCP3physical
22065421
HAT1_ARATHHAT1physical
22065421
ERF81_ARATHERF12physical
22065421
NAC55_ARATHNAC3physical
22065421
TCP16_ARATHTCP16physical
22065421
TCP23_ARATHAT1G35560physical
22065421
TGA6_ARATHTGA6physical
22065421
WRK30_ARATHWRKY30physical
22065421
IAA7_ARATHIAA7physical
22065421
MYB98_ARATHMYB98physical
22065421
BBM_ARATHBBMphysical
22065421
BZR1_ARATHBZR1physical
24938363

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TPR3_ARATH

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Related Literatures of Post-Translational Modification

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