dbPTM

HFB2B_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HFB2B_ARATH
UniProt AC	Q9T0D3
Protein Name	Heat stress transcription factor B-2b
Gene Name	HSFB2B
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	377
Subcellular Localization	Nucleus .
Protein Description	Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE)..
Protein Sequence	MPGEQTGETPTVAGVGGGGAGCSAGNSGGSSGCGAGGGGGGSGGGGGGGGDSQRSIPTPFLTKTYQLVEDPVYDELISWNEDGTTFIVWRPAEFARDLLPKYFKHNNFSSFVRQLNTYGFRKVVPDRWEFSNDCFKRGEKILLRDIQRRKISQPAMAAAAAAAAAAVAASAVTVAAVPVVAHIVSPSNSGEEQVISSNSSPAAAAAAIGGVVGGGSLQRTTSCTTAPELVEENERLRKDNERLRKEMTKLKGLYANIYTLMANFTPGQEDCAHLLPEGKPLDLLPERQEMSEAIMASEIETGIGLKLGEDLTPRLFGVSIGVKRARREEELGAAEEEDDDRREAAAQEGEQSSDVKAEPMEENNSGNHNGSWLELGK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
220	Phosphorylation	GGGSLQRTTSCTTAP CCCCCCCCCCCCCCH	15.31	23776212
221	Phosphorylation	GGSLQRTTSCTTAPE CCCCCCCCCCCCCHH	24.80	23776212
222	Phosphorylation	GSLQRTTSCTTAPEL CCCCCCCCCCCCHHH	14.62	23776212
224	Phosphorylation	LQRTTSCTTAPELVE CCCCCCCCCCHHHHH	26.26	23776212
225	Phosphorylation	QRTTSCTTAPELVEE CCCCCCCCCHHHHHH	44.54	23776212
312	Phosphorylation	LKLGEDLTPRLFGVS CCCCCCCCHHHHCEE	20.77	29654922
352	Phosphorylation	AAQEGEQSSDVKAEP HHHHCCCCCCCCCCC	24.97	30407730
353	Phosphorylation	AQEGEQSSDVKAEPM HHHCCCCCCCCCCCC	46.23	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HFB2B_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HFB2B_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HFB2B_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HFB2B_ARATH	AT-HSFB2B	physical	19945192
Y5436_ARATH	AT5G43560	physical	19945192
PSBP1_ARATH	PSBP-1	physical	19945192

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HFB2B_ARATH

Related Literatures of Post-Translational Modification