SYP41_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SYP41_ARATH
• UniProt AC: O65359
• Protein Name: Syntaxin-41
• Gene Name: SYP41
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 322
• Subcellular Localization: Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. SYP41 is found in a different region of the TGN than SYP42.
• Protein Description: Vesicle trafficking protein that functions in the secretory pathway..
• Protein Sequence: MATRNRTLLFRKYRNSLRSVRAPLSSSSLTGTRSGGVGPVIEMASTSLLNPNRSYAPISTEDPGTSSKGAITVGLPPAWVDVSEEISVNIQRARTKMAELGKAHAKALMPSFGDGKEDQHNIESLTQEITFLLKKSEKQLQRLSASGPSEDSNVRKNVQRSLATDLQLLSMELRKKQSTYLKRLRQQKEDGMDLEMNLSRNRYRPEEDDFGDMLNEHQMSKIKKSEEVSVEREKEIQQVVESVNDLAQIMKDLSALVIDQGTIVDRIDYNIENVATTVEDGLKQLQKAERTQRHGGMVKCASVLVILCFIMLLLLILKEIFL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
19	Phosphorylation	KYRNSLRSVRAPLSS HHHHHHHHCCCCCCC	22.65	28295753
25	Phosphorylation	RSVRAPLSSSSLTGT HHCCCCCCCCCCCCC	27.41	28295753
28	Phosphorylation	RAPLSSSSLTGTRSG CCCCCCCCCCCCCCC	31.72	28295753
32	Phosphorylation	SSSSLTGTRSGGVGP CCCCCCCCCCCCCHH	19.20	28295753
170	Phosphorylation	ATDLQLLSMELRKKQ HHHHHHHHHHHHHHH	20.85	24243849

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SYP41_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SYP41_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SYP41_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SYP61_ARATH	SYP61	physical	11739776
SYP42_ARATH	SYP42	physical	11739776
VTI12_ARATH	VTI1B	physical	11739776
VTI12_ARATH	VTI1B	physical	15919093
YKT61_ARATH	YKT61	physical	15919093
YKT62_ARATH	ATYKT62	physical	15919093
SYP61_ARATH	SYP61	physical	15919093
VPS45_ARATH	VPS45	physical	24556609
JAL34_ARATH	AT3G16460	physical	24556609
RS41_ARATH	AT2G17360	physical	24556609
RL111_ARATH	RPL16A	physical	24556609
RL171_ARATH	AT1G27400	physical	24556609
RL31_ARATH	RP1	physical	24556609
RS232_ARATH	AT5G02960	physical	24556609
VA721_ARATH	VAMP721	physical	24556609
RS241_ARATH	AT3G04920	physical	24556609
RS193_ARATH	AT5G61170	physical	24556609
RL81_ARATH	EMB2296	physical	24556609
RS191_ARATH	AT3G02080	physical	24556609
ENPL_ARATH	SHD	physical	24556609
RS262_ARATH	AT2G40510	physical	24556609
RS21_ARATH	XW6	physical	24556609
SYP43_ARATH	SYP43	physical	24556609
RS91_ARATH	AT5G15200	physical	24556609
RL191_ARATH	emb2386	physical	24556609
RL352_ARATH	AT2G39390	physical	24556609
RL101_ARATH	SAC52	physical	24556609
RS162_ARATH	AT3G04230	physical	24556609
MD37A_ARATH	BIP1	physical	24556609
VPS45_ARATH	VPS45	physical	10888666
VTI12_ARATH	VTI1B	physical	10888666

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.