ENPL_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ENPL_ARATH
• UniProt AC: Q9STX5
• Protein Name: Endoplasmin homolog {ECO:0000305}
• Gene Name: HSP90-7 {ECO:0000303|PubMed:11599565}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 823
• Subcellular Localization: Endoplasmic reticulum lumen.
• Protein Description: May have a molecular chaperone role in the processing of secreted materials. Required for shoot apical meristem (SAM), root apical meristem (RAM) and floral meristem (FM) formation, probably by regulating the folding of CLAVATA proteins (CLVs). Also involved in pollen tube elongation. [PubMed: 11867518 Involved in resistance to tunicamycin- or high calcium-induced ER stresses. Possesses ATPase activity]
• Protein Sequence: MRKRTLVSVLFLFSLLFLLPDQGRKLHANAEESSDDVTDPPKVEEKIGGHGGLSTDSDVVHRESESMSKKTLRSNAEKFEFQAEVSRLMDIIINSLYSNKDIFLRELISNASDALDKIRFLALTDKDVLGEGDTAKLEIQIKLDKAKKILSIRDRGIGMTKEDLIKNLGTIAKSGTSAFVEKMQSSGDLNLIGQFGVGFYSAYLVADYIEVISKHNDDSQYVWESKANGKFAVSEDTWNEPLGRGTEIRLHLRDEAGEYLEESKLKELVKRYSEFINFPISLWASKEVETEVPVEEDESADEETETTSTEEEKEEDAEEEDGEKKQKTKKVKETVYEWELLNDVKAIWLRSPKEVTEEEYTKFYHSLSKDFTDEKPMAWSHFNAEGDVEFKAVLYVPPKAPHDLYESYYNSNKANLKLYVRRVFISDEFDELLPKYLSFLKGLVDSDTLPLNVSREMLQQHSSLKTIKKKLIRKALDMIRKLAEEDPDEIHDDEKKDVEKSGENDEKKGQYTKFWNEFGKSVKLGIIEDAANRNRLAKLLRFETTKSDGKLTSLDQYIKRMKKSQKDIFYITGSSKEQLEKSPFLERLIKKGYEVIFFTDPVDEYLMQYLMDYEDKKFQNVSKEGLKVGKDSKDKELKEAFKELTKWWKGNLASENVDDVKISNRLADTPCVVVTSKFGWSANMERIMQSQTLSDANKQAYMRGKRVLEINPRHPIIKELKDRIASDPEDESVKETAQLMYQTALIESGFILTDPKDFAARIYNSVKSGLNISPDAVADEEIEAAEEPETSEATETKSDDLAGGLNIEAEPVEQQEENTKDEL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
54	Phosphorylation	IGGHGGLSTDSDVVH CCCCCCCCCCHHCHH	33.18	29654922
109	Phosphorylation	IFLRELISNASDALD HHHHHHHHCHHHHHH	38.68	24894044
110	N-linked_Glycosylation	FLRELISNASDALDK HHHHHHHCHHHHHHH	36.15	-
185	Phosphorylation	AFVEKMQSSGDLNLI HHHHHHHCCCCCEEE	32.56	29654922
186	Phosphorylation	FVEKMQSSGDLNLIG HHHHHHCCCCCEEEE	21.31	29654922
234	Phosphorylation	ANGKFAVSEDTWNEP CCCEEEECCCCCCCC	26.73	19880383
290	Phosphorylation	WASKEVETEVPVEED HCCCCEECCCCCCCC	47.67	23776212
299	Phosphorylation	VPVEEDESADEETET CCCCCCCCCCCCCCC	54.03	23776212
304	Phosphorylation	DESADEETETTSTEE CCCCCCCCCCCCCHH	36.26	23776212
306	Phosphorylation	SADEETETTSTEEEK CCCCCCCCCCCHHHH	33.20	23776212
307	Phosphorylation	ADEETETTSTEEEKE CCCCCCCCCCHHHHH	27.67	23776212
308	Phosphorylation	DEETETTSTEEEKEE CCCCCCCCCHHHHHH	41.04	23776212
309	Phosphorylation	EETETTSTEEEKEED CCCCCCCCHHHHHHH	45.37	23776212
452	N-linked_Glycosylation	DSDTLPLNVSREMLQ CCCCCCCCCCHHHHH	27.98	-
593	Phosphorylation	ERLIKKGYEVIFFTD HHHHHCCCEEEEECC	18.86	28295753
599	Phosphorylation	GYEVIFFTDPVDEYL CCEEEEECCCHHHHH	28.75	28295753
605	Phosphorylation	FTDPVDEYLMQYLMD ECCCHHHHHHHHHCC	11.74	28295753
609	Phosphorylation	VDEYLMQYLMDYEDK HHHHHHHHHCCCCCH	7.05	28295753
613	Phosphorylation	LMQYLMDYEDKKFQN HHHHHCCCCCHHHCC	16.44	28295753
620	N-linked_Glycosylation	YEDKKFQNVSKEGLK CCCHHHCCCCHHCCC	43.07	-
688	Sulfoxidation	SANMERIMQSQTLSD CCCHHHHHHHCCCCH	3.82	23289948
690	Phosphorylation	NMERIMQSQTLSDAN CHHHHHHHCCCCHHH	14.04	25561503
692	Phosphorylation	ERIMQSQTLSDANKQ HHHHHHCCCCHHHHH	33.21	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ENPL_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ENPL_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ENPL_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SMT2_ARATH	SMT2	physical	25297550
PER42_ARATH	PRXR1	physical	25297550
NRT32_ARATH	AT4G24730	physical	25297550
ADPRM_ARATH	AT4G24730	physical	25297550
U87A2_ARATH	AT2G30140	physical	25297550
PLY18_ARATH	AT4G24780	physical	25297550
ACOX1_ARATH	ACX1	physical	25297550

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.