SEGN_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SEGN_HUMAN
• UniProt AC: O76038
• Protein Name: Secretagogin
• Gene Name: SCGN
• Organism: Homo sapiens (Human).
• Sequence Length: 276
• Subcellular Localization: Cytoplasm. Secreted. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions (By similarity). Detectabl
• Protein Sequence: MDSSREPTLGRLDAAGFWQVWQRFDADEKGYIEEKELDAFFLHMLMKLGTDDTVMKANLHKVKQQFMTTQDASKDGRIRMKELAGMFLSEDENFLLLFRRENPLDSSVEFMQIWRKYDADSSGFISAAELRNFLRDLFLHHKKAISEAKLEEYTGTMMKIFDRNKDGRLDLNDLARILALQENFLLQFKMDACSTEERKRDFEKIFAYYDVSKTGALEGPEVDGFVKDMMELVQPSISGVDLDKFREILLRHCDVNKDGKIQKSELALCLGLKINP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
146	Phosphorylation	LHHKKAISEAKLEEY HHHHHHHCHHHHHHH	36.04	22798277
153	Phosphorylation	SEAKLEEYTGTMMKI CHHHHHHHHCCCHHH	10.90	-
154	Phosphorylation	EAKLEEYTGTMMKIF HHHHHHHHCCCHHHH	29.47	-
156	Phosphorylation	KLEEYTGTMMKIFDR HHHHHHCCCHHHHCC	13.29	-
208	Phosphorylation	DFEKIFAYYDVSKTG HHHHHHHHEECCCCC	6.88	19835603
209	Phosphorylation	FEKIFAYYDVSKTGA HHHHHHHEECCCCCC	13.36	19835603
236	Phosphorylation	MMELVQPSISGVDLD HHHHHCCCCCCCCHH	16.58	27251275
238	Phosphorylation	ELVQPSISGVDLDKF HHHCCCCCCCCHHHH	36.78	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SEGN_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SEGN_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SEGN_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ATF7_HUMAN	ATF7	physical	26186194
ATF2_HUMAN	ATF2	physical	26186194
ZMYM4_HUMAN	ZMYM4	physical	26186194
GOGB1_HUMAN	GOLGB1	physical	26186194
CROCC_HUMAN	CROCC	physical	26186194
KIF14_HUMAN	KIF14	physical	26186194
RAVR1_HUMAN	RAVER1	physical	26186194
OPA1_HUMAN	OPA1	physical	26186194
CDC23_HUMAN	CDC23	physical	26186194
RBP2_HUMAN	RANBP2	physical	26186194
AGGF1_HUMAN	AGGF1	physical	26186194
ESYT1_HUMAN	ESYT1	physical	26186194
SNP23_HUMAN	SNAP23	physical	26186194
DOC2A_HUMAN	DOC2A	physical	26186194
BBX_HUMAN	BBX	physical	26186194
BBS7_HUMAN	BBS7	physical	26186194
NBR1_HUMAN	NBR1	physical	26186194
DNA2_HUMAN	DNA2	physical	26186194
NPRL3_HUMAN	NPRL3	physical	26186194
PHKG2_HUMAN	PHKG2	physical	26186194
SGPP1_HUMAN	SGPP1	physical	26186194
STX4_HUMAN	STX4	physical	26186194
AGGF1_HUMAN	AGGF1	physical	28514442
RAVR1_HUMAN	RAVER1	physical	28514442
ATF7_HUMAN	ATF7	physical	28514442
KIF14_HUMAN	KIF14	physical	28514442
DOC2A_HUMAN	DOC2A	physical	28514442
PHKG2_HUMAN	PHKG2	physical	28514442
NBR1_HUMAN	NBR1	physical	28514442
GOGB1_HUMAN	GOLGB1	physical	28514442
ATF2_HUMAN	ATF2	physical	28514442
OPA1_HUMAN	OPA1	physical	28514442
CDC23_HUMAN	CDC23	physical	28514442
SNP23_HUMAN	SNAP23	physical	28514442
BBX_HUMAN	BBX	physical	28514442
SGPP1_HUMAN	SGPP1	physical	28514442
NPRL3_HUMAN	NPRL3	physical	28514442
ZMYM4_HUMAN	ZMYM4	physical	28514442
CROCC_HUMAN	CROCC	physical	28514442
STX4_HUMAN	STX4	physical	28514442
ESYT1_HUMAN	ESYT1	physical	28514442
BBS7_HUMAN	BBS7	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.