RUNT_DROME - dbPTM
RUNT_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RUNT_DROME
UniProt AC P22814
Protein Name Segmentation protein Runt
Gene Name run
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 510
Subcellular Localization Nucleus .
Protein Description Plays a pivotal role in regulating the expression of other pair-rule genes such as eve, ftz, and h..
Protein Sequence MHLPAGPTMVANNTQVLAAAAAAAAAAAAAVAQGPGPQQSSNATTASAIAINPAQSLANTSTHSASSTGSSTPDLSTNNTSSSSNATTSPQNSAKMPSSMTDMFASLHEMLQEYHGELAQTGSPSILCSALPNHWRSNKSLPGAFKVIALDDVPDGTLVSIKCGNDENYCGELRNCTTTMKNQVAKFNDLRFVGRSGRGKSFTLTITIATYPVQIASYSKAIKVTVDGPREPRSKQSYGYPHPGAFNPFMLNPAWLDAAYMTYGYADYFRHQAAAQAAQVHHPALAKSSASSVSPNPNPSVATSSSSAVQPSEYPHPAAAVAAAAGQPAAMMPSPPGAAPATPYAIPQFPFNHVAAAAAAKAATPHAFHPYNFAAAAGLRARNAALHHQSEPVHVSPASSRPSSSSPTQQHVLLKLNTSIETSSIHEQSASDGDSDDEQIDVVKSEFDLDKSLDVAPLRMRCDLKAPSAMKPLYHESGPGAVANSRQPSPETTTKIKSAAVQQKTVWRPY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of RUNT_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RUNT_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RUNT_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RUNT_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
BGB_DROMEBgbphysical
14605208
BRO_DROMEBrophysical
14605208
RL38_DROMERpL38genetic
8849891
RS25_DROMERpS25genetic
8849891
RL36_DROMERpL36genetic
8849891
RS10B_DROMERpS10bgenetic
8849891
AFF4_DROMElilligenetic
17137570
RL27A_DROMERpL27Agenetic
8849891
TRA1_DROMENipped-Agenetic
8849891
BRO_DROMEBrogenetic
10393111
HDAC1_DROMERpd3genetic
12145660
RS17_DROMERpS17genetic
8849891
CTBP_DROMECtBPgenetic
12145660
GROU_DROMEgrogenetic
12145660
TTKB_DROMEttkgenetic
12145660
TTKA_DROMEttkgenetic
12145660
BGB_DROMEBgbphysical
8622696
BRO_DROMEBrophysical
8622696
BRO_DROMEBrophysical
9271433
HLES_DROMEHphysical
21325629
GROU_DROMEgrophysical
9271433
GROU_DROMEgrophysical
21325629

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RUNT_DROME

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Related Literatures of Post-Translational Modification

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