RL3L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RL3L_HUMAN
• UniProt AC: Q92901
• Protein Name: 60S ribosomal protein L3-like
• Gene Name: RPL3L
• Organism: Homo sapiens (Human).
• Sequence Length: 407
• Protein Sequence: MSHRKFSAPRHGHLGFLPHKRSHRHRGKVKTWPRDDPSQPVHLTAFLGYKAGMTHTLREVHRPGLKISKREEVEAVTIVETPPLVVVGVVGYVATPRGLRSFKTIFAEHLSDECRRRFYKDWHKSKKKAFTKACKRWRDTDGKKQLQKDFAAMKKYCKVIRVIVHTQMKLLPFRQKKAHIMEIQLNGGTVAEKVAWAQARLEKQVPVHSVFSQSEVIDVIAVTKGRGVKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVGCSIARAGQKGYHHRTELNKKIFRIGRGPHMEDGKLVKNNASTSYDVTAKSITPLGGFPHYGEVNNDFVMLKGCIAGTKKRVITLRKSLLVHHSRQAVENIELKFIDTTSKFGHGRFQTAQEKRAFMGPQKKHLEKETPETSGDL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MSHRKFSAPRHGHL -CCCCCCCCCCCCCC	40.16	23927012
38	Phosphorylation	TWPRDDPSQPVHLTA CCCCCCCCCCCEEHE	54.86	27251275
44	Phosphorylation	PSQPVHLTAFLGYKA CCCCCEEHEEECHHC	10.65	27251275
50	Ubiquitination	LTAFLGYKAGMTHTL EHEEECHHCCCCCHH	36.34	22817900
55	Ubiquitination	GYKAGMTHTLREVHR CHHCCCCCHHHHHCC	17.63	22817900
125	Phosphorylation	FYKDWHKSKKKAFTK HHHHHHHHHHHHHHH	36.50	-
246	Ubiquitination	KLPRKTHKGLRKVAC CCCCCCCCCCCCEEE	65.94	22817900
250	Methylation	KTHKGLRKVACIGAW CCCCCCCCEEEECCC	38.95	-
250	Sumoylation	KTHKGLRKVACIGAW CCCCCCCCEEEECCC	38.95	-
250	Ubiquitination	KTHKGLRKVACIGAW CCCCCCCCEEEECCC	38.95	21963094
250	Sumoylation	KTHKGLRKVACIGAW CCCCCCCCEEEECCC	38.95	-
251	Ubiquitination	THKGLRKVACIGAWH CCCCCCCEEEECCCC	4.20	22817900
253	S-palmitoylation	KGLRKVACIGAWHPA CCCCCEEEECCCCHH	3.10	21044946
255	Ubiquitination	LRKVACIGAWHPARV CCCEEEECCCCHHHH	23.62	21963094
305	Phosphorylation	LVKNNASTSYDVTAK EECCCCCCCCEEECC	28.97	29514088
306	Phosphorylation	VKNNASTSYDVTAKS ECCCCCCCCEEECCE	19.48	29514088
307	Phosphorylation	KNNASTSYDVTAKSI CCCCCCCCEEECCEE	17.96	29514088
310	Phosphorylation	ASTSYDVTAKSITPL CCCCCEEECCEEECC	26.01	29514088
356	Phosphorylation	KSLLVHHSRQAVENI HHHHHHCCHHHHHCE	15.94	18510355
370	Phosphorylation	IELKFIDTTSKFGHG EEEEEEECCCCCCCC	28.31	29514088
371	Phosphorylation	ELKFIDTTSKFGHGR EEEEEECCCCCCCCC	26.60	29514088
372	Phosphorylation	LKFIDTTSKFGHGRF EEEEECCCCCCCCCC	28.25	29514088
373	Sumoylation	KFIDTTSKFGHGRFQ EEEECCCCCCCCCCC	53.96	-
373	Ubiquitination	KFIDTTSKFGHGRFQ EEEECCCCCCCCCCC	53.96	23000965
373	Methylation	KFIDTTSKFGHGRFQ EEEECCCCCCCCCCC	53.96	7214009
373	Sumoylation	KFIDTTSKFGHGRFQ EEEECCCCCCCCCCC	53.96	-
373	Acetylation	KFIDTTSKFGHGRFQ EEEECCCCCCCCCCC	53.96	7214009
378	Ubiquitination	TSKFGHGRFQTAQEK CCCCCCCCCCHHHHH	18.15	21890473
400	Phosphorylation	KKHLEKETPETSGDL HHHHHCCCCCCCCCC	37.18	26437602
404	Phosphorylation	EKETPETSGDL---- HCCCCCCCCCC----	28.75	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RL3L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RL3L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RL3L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
RL6_HUMAN	RPL6	physical	22939629
RL13_HUMAN	RPL13	physical	26344197
RL14_HUMAN	RPL14	physical	26344197
RL15_HUMAN	RPL15	physical	26344197
RL18_HUMAN	RPL18	physical	26344197
RL23A_HUMAN	RPL23A	physical	26344197
RL27A_HUMAN	RPL27A	physical	26344197
RL30_HUMAN	RPL30	physical	26344197
RL37A_HUMAN	RPL37A	physical	26344197
RL39_HUMAN	RPL39	physical	26344197
RL6_HUMAN	RPL6	physical	26344197
RL9_HUMAN	RPL9	physical	26344197
RS20_HUMAN	RPS20	physical	26344197
RS23_HUMAN	RPS23	physical	26344197
RS26_HUMAN	RPS26	physical	26344197
RS8_HUMAN	RPS8	physical	26344197
RS9_HUMAN	RPS9	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.