NU50A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NU50A_ARATH
• UniProt AC: Q9C829
• Protein Name: Nuclear pore complex protein NUP50A {ECO:0000303|PubMed:21189294}
• Gene Name: NUP50A {ECO:0000303|PubMed:21189294}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 440
• Subcellular Localization: Nucleus, nucleoplasm . Nucleus, nuclear pore complex .
• Protein Description: Probably involved in nucleocytoplasmic transport via its interactions with importins and Ran, rather than by forming part of the nuclear pore complex (NPC) scaffolding..
• Protein Sequence: MGDSENVQQPSKKRGALKQLSRDNPGLDDDDDSAELESGTFKKASDEVLASRRIVRVKRKEPSAAPVAASNPFAGIQLVPTTAPASTPVGTNAPLAESKLAPAEAVVEDNQKASDIEEGDEVDSKKVDVKDAVGEETEKTKDKDDNHCGKSADVQVAATEVAQMVSCDTNVCNNAVEGTDQTDFPLEKDSGGDQAEKKEKEGNGIEEADKNGDNGAFSSFQQHSSNKNAFTGLASTEASGSSFSFGLVSQDGSTGTGSLFGFGLPSSNSSSIFGATGSSIIKKSEGSGFPPKQEVSTETGEENEKVAFSADSIMFEYLDGGWKERGKGELKVNVSSNDGKARLVMRAKGNYRLILNASLYPEMKLANMDKKGITFACVNSVSEGKEGLSTFALKFKDPTIVEEFRVAIDKHKDSKPMEKAAEKSALPLKTPENSPTATDT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MGDSENVQQ ------CCCCHHCCC		22223895
4	Phosphorylation	----MGDSENVQQPS ----CCCCHHCCCCH		30407730
21	Phosphorylation	RGALKQLSRDNPGLD HHHHHHHHCCCCCCC		23776212
33	Phosphorylation	GLDDDDDSAELESGT CCCCCCCHHHHHCCC		30291188
38	Phosphorylation	DDSAELESGTFKKAS CCHHHHHCCCEEHHC		23776212
40	Phosphorylation	SAELESGTFKKASDE HHHHHCCCEEHHCHH		23776212
45	Phosphorylation	SGTFKKASDEVLASR CCCEEHHCHHHHHHC		25561503
114	Phosphorylation	VEDNQKASDIEEGDE ECCCCCHHCCCCCCC		30291188
124	Phosphorylation	EEGDEVDSKKVDVKD CCCCCCCCCCCCHHH		23776212
424	Phosphorylation	MEKAAEKSALPLKTP HHHHHHHHCCCCCCC		23776212
430	Phosphorylation	KSALPLKTPENSPTA HHCCCCCCCCCCCCC		24601666
434	Phosphorylation	PLKTPENSPTATDT- CCCCCCCCCCCCCC-		24601666
436	Phosphorylation	KTPENSPTATDT--- CCCCCCCCCCCC---		23776212
438	Phosphorylation	PENSPTATDT----- CCCCCCCCCC-----		23776212
440	Phosphorylation	NSPTATDT------- CCCCCCCC-------		23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NU50A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NU50A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NU50A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IMPA1_ARATH	IMPA-1	physical	21189294
HSP7F_ARATH	cpHsc70-1	physical	21189294
HSP7G_ARATH	CPHSC70-2EAT SHOCK PROTEIN 70-2	physical	21189294
IMPA3_ARATH	MOS6	physical	21189294
EFTU_ARATH	RABE1b	physical	21189294
MD37E_ARATH	HSC70-1	physical	21189294
MD37D_ARATH	AT5G02490	physical	21189294
MD37C_ARATH	HSP70	physical	21189294
BGL37_ARATH	TGG2	physical	21189294
NUCL1_ARATH	NUC-L1	physical	21189294
RAN1_ARATH	RAN-1	physical	21189294
HSP7P_ARATH	AT1G79920	physical	21189294
HSP7O_ARATH	HSP91	physical	21189294
RL182_ARATH	RPL18	physical	21189294
RL101_ARATH	SAC52	physical	21189294
HDT3_ARATH	HD2C	physical	21189294
RK1_ARATH	AT3G63490	physical	21189294
PUM5_ARATH	PUM5	physical	21189294
TOR_ARATH	TOR	physical	21189294
MUB1_ARATH	MUB1	physical	21189294
Y4791_ARATH	AT4G17910	physical	21189294
MTM1_ARATH	MTM1	physical	21189294
LUMI_ARATH	LD	physical	21189294
MAOP1_ARATH	NADP-ME1	physical	21189294
PPR41_ARATH	AT1G13630	physical	21189294
PCAP1_ARATH	PCAP1	physical	21189294
HXK4_ARATH	ATHXK4	physical	21189294
NU50B_ARATH	AT3G15970	physical	21189294
RCH2_ARATH	AT3G24240	physical	21189294
TDT_ARATH	TDT	physical	21189294
MD37A_ARATH	BIP1	physical	21189294
FOLT1_ARATH	FOLT1	physical	21189294

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.