dbPTM

NU50B_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NU50B_ARATH
UniProt AC	Q9LW88
Protein Name	Nuclear pore complex protein NUP50B {ECO:0000303\|PubMed:21189294}
Gene Name	NUP50B {ECO:0000303\|PubMed:21189294}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	465
Subcellular Localization	Nucleus, nucleoplasm . Nucleus, nuclear pore complex .
Protein Description	Probably involved in nucleocytoplasmic transport via its interactions with importins and Ran, rather than by forming part of the nuclear pore complex (NPC) scaffolding..
Protein Sequence	MGDSDNAIPFSRKRTALKELSRDNPGLDDDDEDTSALESGTFNTASKEVLASRRIIRVRRTDRSATAPPASNPFTGIRLVPFTAPAPSTAAAETTKPLSAGKQETLADGRSDATKETDGDSKEKSDAIDAVGKQETQGDEISAKTKDIIDGGEKEMSEAVNSVEGGGAVNKNEDEIKTTMVTEVAAGEETVKDDNNNSNTVEGSDCVVKDTGGNQTEKEGKEGDGNEDTEKNGDSGALSSFHQHSSSKNAFTGLASTGFSASSFSFGLVPQEGSTGSGSEQSSFSFGQANNGNSSLFGASVATSITTKSTETTTAFPSKQDVSVETGEENEKAAFTADSVMFEYLEGGWKERGKGELKVNISTTENRKARLVMRSKGNYRLTLNASLYPEMKLAKMDKKGITFACVNSVSDAKDGLSTLALKFKDPTVVEEFRAVIEEHKDSKPSVAEAAAPLKTPENSPSAEDA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
2	Acetylation	------MGDSDNAIP ------CCCCCCCCC	-
4	Phosphorylation	----MGDSDNAIPFS ----CCCCCCCCCHH	30589143
64	Phosphorylation	RVRRTDRSATAPPAS EEEECCCCCCCCCCC	27288362
66	Phosphorylation	RRTDRSATAPPASNP EECCCCCCCCCCCCC	27288362
125	Phosphorylation	DGDSKEKSDAIDAVG CCCCHHHHHHHHHHC	-
309	Phosphorylation	ATSITTKSTETTTAF EEECEECCCCCCCCC	25561503
310	Phosphorylation	TSITTKSTETTTAFP EECEECCCCCCCCCC	25561503
442	Phosphorylation	VIEEHKDSKPSVAEA HHHHCCCCCCCHHHH	23776212
445	Phosphorylation	EHKDSKPSVAEAAAP HCCCCCCCHHHHHCC	23776212
455	Phosphorylation	EAAAPLKTPENSPSA HHHCCCCCCCCCCCC	30291188
459	Phosphorylation	PLKTPENSPSAEDA- CCCCCCCCCCCCCC-	30291188
461	Phosphorylation	KTPENSPSAEDA--- CCCCCCCCCCCC---	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NU50B_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NU50B_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NU50B_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NU50B_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NU50B_ARATH

Related Literatures of Post-Translational Modification