MAGAC_HUMAN - dbPTM
MAGAC_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MAGAC_HUMAN
UniProt AC P43365
Protein Name Melanoma-associated antigen 12
Gene Name MAGEA12
Organism Homo sapiens (Human).
Sequence Length 314
Subcellular Localization
Protein Description Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines..
Protein Sequence MPLEQRSQHCKPEEGLEAQGEALGLVGAQAPATEEQETASSSSTLVEVTLREVPAAESPSPPHSPQGASTLPTTINYTLWSQSDEGSSNEEQEGPSTFPDLETSFQVALSRKMAELVHFLLLKYRAREPFTKAEMLGSVIRNFQDFFPVIFSKASEYLQLVFGIEVVEVVRIGHLYILVTCLGLSYDGLLGDNQIVPKTGLLIIVLAIIAKEGDCAPEEKIWEELSVLEASDGREDSVFAHPRKLLTQDLVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHLLKISGGPHISYPPLHEWAFREGEE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
112UbiquitinationFQVALSRKMAELVHF
HHHHHHHHHHHHHHH		38.8021963094
132UbiquitinationRAREPFTKAEMLGSV
HCCCCCCHHHHHHHH		42.6123000965
152PhosphorylationDFFPVIFSKASEYLQ
HHHHHHHHHHHHHHH		19.0524719451
220UbiquitinationGDCAPEEKIWEELSV
CCCCCHHHHHHHHHE		52.0021963094
244UbiquitinationSVFAHPRKLLTQDLV
CCCCCHHHHHCHHHH		52.9123000965
258PhosphorylationVQENYLEYRQVPGSD
HHHCCHHHCCCCCCC		12.07-
285UbiquitinationLVETSYVKVLHHLLK
HHHHHHHHHHHHHHH		30.7421963094
292UbiquitinationKVLHHLLKISGGPHI
HHHHHHHHHCCCCCC		40.9829967540
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MAGAC_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MAGAC_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MAGAC_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
STA5A_HUMANSTAT5Aphysical
16189514
ANF_HUMANNPPAphysical
25416956
ZN33B_HUMANZNF33Bphysical
25416956
SCMH1_HUMANSCMH1physical
25416956
DPOLL_HUMANPOLLphysical
25416956
ABI3_HUMANABI3physical
25416956
TBC19_HUMANTBC1D19physical
25416956
MFR1L_HUMANMTFR1Lphysical
25416956
FND11_HUMANC20orf195physical
25416956
FAKD3_HUMANFASTKD3physical
25416956
CLIP4_HUMANCLIP4physical
25416956
MTFR2_HUMANMTFR2physical
25416956
KANL1_HUMANKANSL1physical
25416956
NANO2_HUMANNANOS2physical
25416956
CP087_HUMANC16orf87physical
25416956
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MAGAC_HUMAN

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Related Literatures of Post-Translational Modification

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