MFR1L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MFR1L_HUMAN
• UniProt AC: Q9H019
• Protein Name: Mitochondrial fission regulator 1-like
• Gene Name: MTFR1L
• Organism: Homo sapiens (Human).
• Sequence Length: 292
• Protein Sequence: MSGMEATVTIPIWQNKPHGAARSVVRRIGTNLPLKPCARASFETLPNISDLCLRDVPPVPTLADIAWIAADEEETYARVRSDTRPLRHTWKPSPLIVMQRNASVPNLRGSEERLLALKKPALPALSRTTELQDELSHLRSQIAKIVAADAASASLTPDFLSPGSSNVSSPLPCFGSSFHSTTSFVISDITEETEVEVPELPSVPLLCSASPECCKPEHKAACSSSEEDDCVSLSKASSFADMMGILKDFHRMKQSQDLNRSLLKEEDPAVLISEVLRRKFALKEEDISRKGN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSGMEATVT ------CCCCCEEEE		-
7	Phosphorylation	-MSGMEATVTIPIWQ -CCCCCEEEEEEECC		23401153
9	Phosphorylation	SGMEATVTIPIWQNK CCCCEEEEEEECCCC		23401153
30	Phosphorylation	SVVRRIGTNLPLKPC HHHHHHCCCCCCCCC		28857561
41	Phosphorylation	LKPCARASFETLPNI CCCCCCCCCCCCCCH		30278072
44	Phosphorylation	CARASFETLPNISDL CCCCCCCCCCCHHHH		25693802
49	Phosphorylation	FETLPNISDLCLRDV CCCCCCHHHHCCCCC		28450419
76	Phosphorylation	AADEEETYARVRSDT ECCHHHHHHHHHCCC		27642862
81	Phosphorylation	ETYARVRSDTRPLRH HHHHHHHCCCCCCCC		-
83	Phosphorylation	YARVRSDTRPLRHTW HHHHHCCCCCCCCCC		24719451
93	Phosphorylation	LRHTWKPSPLIVMQR CCCCCCCCCEEEEEC		28555341
103	Phosphorylation	IVMQRNASVPNLRGS EEEECCCCCCCCCCC		29255136
110	Phosphorylation	SVPNLRGSEERLLAL CCCCCCCCHHHHHHH		26055452
126	Phosphorylation	KPALPALSRTTELQD CCCHHHHCCCHHHHH		28555341
136 (in isoform 2)	Phosphorylation	-		27174698
140 (in isoform 2)	Phosphorylation	-		27174698
152 (in isoform 2)	Phosphorylation	-		27174698
153 (in isoform 2)	Phosphorylation	-		27174698
208	Phosphorylation	PSVPLLCSASPECCK CCCCEEECCCHHHCC		26074081
210	Phosphorylation	VPLLCSASPECCKPE CCEEECCCHHHCCHH		26074081
223	Phosphorylation	PEHKAACSSSEEDDC HHHHHCCCCCCCCHH		25159151
224	Phosphorylation	EHKAACSSSEEDDCV HHHHCCCCCCCCHHC		26657352
225	Phosphorylation	HKAACSSSEEDDCVS HHHCCCCCCCCHHCC		26657352
232	Phosphorylation	SEEDDCVSLSKASSF CCCCHHCCHHHHHHH		25159151
234	Phosphorylation	EDDCVSLSKASSFAD CCHHCCHHHHHHHHH		25849741
235	Ubiquitination	DDCVSLSKASSFADM CHHCCHHHHHHHHHH		-
237	Phosphorylation	CVSLSKASSFADMMG HCCHHHHHHHHHHHH		29255136
238	Phosphorylation	VSLSKASSFADMMGI CCHHHHHHHHHHHHH		29255136
247	Ubiquitination	ADMMGILKDFHRMKQ HHHHHHHHHHHHHHH		-
252 (in isoform 3)	Ubiquitination	-		21906983
253	Ubiquitination	LKDFHRMKQSQDLNR HHHHHHHHHCHHHHH		-
255	Phosphorylation	DFHRMKQSQDLNRSL HHHHHHHCHHHHHHH		20068231
261	Phosphorylation	QSQDLNRSLLKEEDP HCHHHHHHHCCCCCH		25159151
264	Ubiquitination	DLNRSLLKEEDPAVL HHHHHHCCCCCHHHH		2190698
273	Phosphorylation	EDPAVLISEVLRRKF CCHHHHHHHHHHHHH		20068231
283	Ubiquitination	LRRKFALKEEDISRK HHHHHCCCHHHHHCC		-
297 (in isoform 1)	Ubiquitination	-		21906983

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MFR1L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MFR1L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MFR1L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CING_HUMAN	CGN	physical	27173435

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.