LHX6_HUMAN - dbPTM
LHX6_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LHX6_HUMAN
UniProt AC Q9UPM6
Protein Name LIM/homeobox protein Lhx6
Gene Name LHX6
Organism Homo sapiens (Human).
Sequence Length 363
Subcellular Localization Nucleus .
Protein Description Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex (By similarity)..
Protein Sequence MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGQASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYTPFSSPERARMVTLHGYIESQVQCGQVHCRLPYTAPPVHLKADMDGPLSNRGEKVILFQY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
185PhosphorylationKVLCRIHYDTMIENL
EEHHEECHHHHHHHH
15.67-
187PhosphorylationLCRIHYDTMIENLKR
HHEECHHHHHHHHHH
16.94-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LHX6_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LHX6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LHX6_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
LDB1_HUMANLDB1physical
26186194
ATG2B_HUMANATG2Bphysical
26186194
SSBP4_HUMANSSBP4physical
26186194
SSBP3_HUMANSSBP3physical
26186194
SSBP2_HUMANSSBP2physical
26186194
ZN507_HUMANZNF507physical
26186194
ARI3B_HUMANARID3Bphysical
26186194
EHMT2_HUMANEHMT2physical
26186194
NUD22_HUMANNUDT22physical
26186194
TF2H2_HUMANGTF2H2physical
26186194
TLE3_HUMANTLE3physical
26186194
TLK2_HUMANTLK2physical
26186194
CARD8_HUMANCARD8physical
26186194
WIPI4_HUMANWDR45physical
26186194
QRIC1_HUMANQRICH1physical
26186194
WDFY1_HUMANWDFY1physical
26186194
TRI33_HUMANTRIM33physical
26186194
SALL2_HUMANSALL2physical
26186194
OTUD4_HUMANOTUD4physical
26186194
KDM5C_HUMANKDM5Cphysical
26186194
RN187_HUMANRNF187physical
26186194
SATB2_HUMANSATB2physical
26186194
ATG2B_HUMANATG2Bphysical
28514442
LDB1_HUMANLDB1physical
28514442
SSBP3_HUMANSSBP3physical
28514442
SSBP4_HUMANSSBP4physical
28514442
NUD22_HUMANNUDT22physical
28514442
SSBP2_HUMANSSBP2physical
28514442
WIPI4_HUMANWDR45physical
28514442
ZN507_HUMANZNF507physical
28514442
RN187_HUMANRNF187physical
28514442
SATB2_HUMANSATB2physical
28514442
KDM5C_HUMANKDM5Cphysical
28514442
ARI3B_HUMANARID3Bphysical
28514442
CARD8_HUMANCARD8physical
28514442
QRIC1_HUMANQRICH1physical
28514442
TLK2_HUMANTLK2physical
28514442
TRI33_HUMANTRIM33physical
28514442
SALL2_HUMANSALL2physical
28514442

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LHX6_HUMAN

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Related Literatures of Post-Translational Modification

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