| UniProt ID | ITA2_DROME | |
|---|---|---|
| UniProt AC | P12080 | |
| Protein Name | Integrin alpha-PS2 | |
| Gene Name | if | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 1396 | |
| Subcellular Localization |
Apical cell membrane Single-pass type I membrane protein . Lateral cell membrane Single-pass type I membrane protein . Basal cell membrane Single-pass type I membrane protein . During mid-oogenesis, localizes to the apical, to the lateral and t |
|
| Protein Description | Alpha-PS2/beta-PS is a receptor for Tig, wb and Ten-m. Involved in the function and/or development of the olfactory system.. | |
| Protein Sequence | MSGDSIHRRRMALHCPITSLILLLIAMSAHGYNIDLPSYVRFRQSSNSMFGFSIAMHKGRSGFYGNQNNVSLIVGAPKFDTSRYQQGVTEAGGVFKCSLNDDDCKLVPFDSKGNNRNVDKEVVDRKSYQWLGATVATGRDSDLVVACAPRYVFHTMTPSRAFRIDPVGTCFTSHNFEEFYEVSPCRTNNWGYHRQGSCQAGFSAAINGNGSRLFIGAPGSWYWQGQTYSIPPDAKFPFKPPLYQPFGTGGMASSHDVTRPENQVFSTSESASVNDDSYLGYSMVTGDFDGDRSEDVAIGMPRGGNLVGRIVVNRWNMANIFNITGRQIGEYFGYSLATSDVDGDGLDDLLIGAPMYTDPDNVEGKYDVGRVYILLQGGPTEEKRWTTEHIRDGYHSKGRFGLALTTLGDVNGDGYGDFAVGAPYDGPEGRGVVYIFHGSPMGPLAKPSQIIKSEQLVEGAPYPRTFGFALSGGLDMDGNTYPDLAVGAYSSDQVFIFKSRPVAAVNAETSFASNSKLISLDDRSCQLVRDHKKVPCMLLTTCWSYTGRYLPEQLDFDVSWLLDAKKLLNPRMFFLRDEGKNIRNQTIRLNYGQKYCLNETVYLLDKVQDKLTPLEVEARYNLRSSRPLDPMVRHRRSILEPVIDQNREIVLRDAINIQKNCGPDNICEPDLKLKVSTVDKYLFGSPEPLVIEVFISNTNEDAFEAAFYMVTPPDLQFRKLQQLGEKKDTPITCSPPTPENNHTLKCDIGNPLESGKIAHFKISLVPEEKYGSSSSYDFYWEANSTNLEKPGSEYDNKIRQSVGIWVDTDLDIKGTSLPDYQLYKADDYKELENATKEDDIGPQVVHIYEIRNNRPSIIEEAEVFIHLPYETIVGDPLMYLLNQPETGGKIQCDDVAFNEYNLLLDEKLVKKSYLQAQGAIWNSAQVSGQSSSSSSSGGASVHIEKARGEGFVRGVLVSNSTDAGDKLSPKQVEQRRQEDTLEALGDASFVHRDRASQAVQEPQVNQTSFTTYSTSSSSSGSGAPSAQLRGHSTQGHIQMAGPVQHTSSSSSSNYRSWPAQQQQQHQQLLLAGSGGSGLGSPVTFNDKSQFGGRNNNFHTGTLDLGTLNRGNVDNELYRSQGQYQNPSQSLGQSQGQFQANANQGHYQGQNQAQFQARNPGFQGQTSYQGQTQYSGQPGGYQTHHVTYSSGSKPYYGRENEDFYDEDNLQQATPGHWSSSSSSSSSSGTRRLRRSNDKDGATEKPLQIDLNSPCQSARCKSIRCVVTNLGTEDGDAAFVAIRARMVAKTMEKLASNVPLNVSTLAVANVTLLPFIGAPKDAIVKTHEIFYKAEPEPLQVPDVVPLWVVVLAACAGALIFLLLVWLLYKCGFFNRNRPTDHSQERQPLRNGYHGDEHL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 69 | N-linked_Glycosylation | GFYGNQNNVSLIVGA CCCCCCCCEEEEEEC | 18.26 | - | |
| 209 | N-linked_Glycosylation | FSAAINGNGSRLFIG CEEEECCCCCEEEEE | 40.56 | - | |
| 322 | N-linked_Glycosylation | WNMANIFNITGRQIG CCCHHHCCCCCCCHH | 27.41 | - | |
| 584 | N-linked_Glycosylation | DEGKNIRNQTIRLNY CCCCCCCCCEEECCC | 39.28 | - | |
| 598 | N-linked_Glycosylation | YGQKYCLNETVYLLD CCCCEECCCEEEHHH | 39.05 | - | |
| 741 | N-linked_Glycosylation | SPPTPENNHTLKCDI CCCCCCCCCEEEECC | 28.05 | - | |
| 783 | N-linked_Glycosylation | YDFYWEANSTNLEKP CEEEEEECCCCCCCC | 37.54 | - | |
| 833 | N-linked_Glycosylation | DDYKELENATKEDDI CCHHHHHHCCCCCCC | 66.58 | - | |
| 959 | N-linked_Glycosylation | VRGVLVSNSTDAGDK EEEEEEECCCCCCCC | 41.26 | - | |
| 1005 | N-linked_Glycosylation | AVQEPQVNQTSFTTY HCCCCCCCCCEEEEE | 33.88 | - | |
| 1299 | N-linked_Glycosylation | LASNVPLNVSTLAVA HHHCCCCCHHHHEEE | 21.44 | - | |
| 1307 | N-linked_Glycosylation | VSTLAVANVTLLPFI HHHHEEEEEEEECCC | 22.25 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ITA2_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ITA2_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ITA2_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| KRAF1_DROME | phl | genetic | 12242240 | |
| DSOR1_DROME | Dsor1 | genetic | 12242240 | |
| ITA1_DROME | mew | genetic | 9527881 | |
| ITA1_DROME | mew | genetic | 9250662 | |
| ECR_DROME | EcR | genetic | 10753511 | |
| GALT3_DROME | pgant3 | genetic | 20371600 | |
| ZASP_DROME | Zasp52 | genetic | 18166658 | |
| SLIT_DROME | sli | genetic | 12040052 | |
| SLIT_DROME | sli | genetic | 1339662 | |
| SRF_DROME | bs | genetic | 1339662 | |
| SRF_DROME | bs | genetic | 9755209 | |
| RL19_DROME | RpL19 | genetic | 8297785 | |
| CANB_DROME | CalpB | genetic | 22827336 | |
| HOW_DROME | how | genetic | 9755209 | |
| ITBX_DROME | mys | genetic | 10532829 | |
| ITBX_DROME | mys | genetic | 12242240 | |
| CSW_DROME | csw | genetic | 12242240 | |
| SOG_DROME | sog | physical | 12835400 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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