UniProt ID | ITA1_DROME | |
---|---|---|
UniProt AC | Q24247 | |
Protein Name | Integrin alpha-PS1 | |
Gene Name | mew | |
Organism | Drosophila melanogaster (Fruit fly). | |
Sequence Length | 1146 | |
Subcellular Localization |
Apical cell membrane Single-pass type I membrane protein . Lateral cell membrane Single-pass type I membrane protein . Basal cell membrane Single-pass type I membrane protein . During mid-oogenesis, localizes to the apical, to the lateral and t |
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Protein Description | Integrin alpha-PS1/beta-PS is a receptor for laminin.. | |
Protein Sequence | MLELPFTTIRPNCRLRQNLGILIILQCVLTCYNFNLEQRLPIVKYGHPHSHFGYSVATHTIGEANGPNKTNCVLVGAPLDQNRQPNTTHSGALWRCPMTQRFDDCEQVITDGRRNFDSEILSPPGNDEIKEDQWMGVTVRSNPLQANGSGGKVIVCAHRYMYIVRENRYGQGLCYLLTNDLQFEEVHEPCKGRPVQRQHEDYGLCQAGTSAALLDDDTMVLGSPGPYTWRGSIWVTQVGGEYLQRDKTTYYSDHSDLNSPVDKYSYLGMSVTGGRFFGHMSYAAGAPRSEGHGQVVIFDKSTDNPIPVHSILDGEQFGSSFGYELATADINGDHRPDLIVAAPLYFTKTEGGAVYVYQNIQDTLPMKYTLKLTGPLESRFGLALANIGDLNKDNCEDLAVGAPYEGNGVVYIYLGSSQGLNSKPAQKIQASELGGTIPNGQPIRTFGISISGNTDLDDNSYPDVVIGAFNSSAAVILLARPIISIQTSVQRKELHNMDPNTPGCLDDPASNLTCFTFRACCSIEPYDEKNKELRLAYSVEAETFDHLKKFSRVFFFDRENKRTNVLSRVVRVHTNGRTECQAVTGYIKANTRDIQTPVRFRLKYSLVEPPLADSALVRLNPILDQTQAHVDFEGTFQKDCGDDDLCESNLIIRVEPNITESSGNEYTLILDETELEVRINVSNLADSAYEAQLFIAHQAGVSYVATKKPTNATCNSYNTTLVACSLGNPMLRDTTTFVTIRFQPKGLEPSEKIMLFHIFANTTSKLVGPERPERDLRVNVVRRAKLNFRGWAIPEQSFYSGSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIFNEGPSTAPKVQMVIHWPYSLYSDPQSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLASGSRENPAYLSAPAQMRMFPSQSRHSFNKSLIHSQRSYYSSSHRDDHSDDTQSNRNRVRRSFLERVTRLERLMYDPESSNAANGKKQDIVELDCNKGATNCVRIECDILNMPALSEAQVVVKARLWNSTLVSEYPRVERVRIFSTATAQIPESYGVEVMDHNNIEVETRAYPELRNQQRDTSIPWLIIILGIVGGLLLLALVTYVLWKVGFFKRIRPTDPTLSGNLEKMNEEKPFLAPSKNTHHVF | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
68 | N-linked_Glycosylation | IGEANGPNKTNCVLV CCCCCCCCCCCEEEE | 66.24 | - | |
86 | N-linked_Glycosylation | LDQNRQPNTTHSGAL CCCCCCCCCCCCCEE | 49.63 | - | |
147 | N-linked_Glycosylation | RSNPLQANGSGGKVI ECCCEEECCCCCEEE | 32.00 | - | |
470 | N-linked_Glycosylation | DVVIGAFNSSAAVIL CEEEEECCCCHHHHH | 34.22 | - | |
511 | N-linked_Glycosylation | CLDDPASNLTCFTFR CCCCHHHCCEEEEEE | 41.28 | - | |
657 | N-linked_Glycosylation | LIIRVEPNITESSGN EEEEECCCEECCCCC | 40.07 | 17893096 | |
680 | N-linked_Glycosylation | TELEVRINVSNLADS CEEEEEEEHHHHCCC | 22.17 | - | |
711 | N-linked_Glycosylation | VATKKPTNATCNSYN EEECCCCCCCCCCCC | 41.60 | 19349973 | |
718 | N-linked_Glycosylation | NATCNSYNTTLVACS CCCCCCCCCEEEEEE | 26.80 | 19349973 | |
761 | N-linked_Glycosylation | MLFHIFANTTSKLVG EEEEEECCCCCCCCC | 32.89 | 19349973 | |
928 | N-linked_Glycosylation | SQSRHSFNKSLIHSQ CCCCCCCCHHHHHHH | 35.70 | - | |
1027 | N-linked_Glycosylation | VVKARLWNSTLVSEY EEEEECCCCCCCCCC | 29.70 | 17893096 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ITA1_DROME !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ITA1_DROME !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ITA1_DROME !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
ITA2_DROME | if | genetic | 8674437 | |
ITA2_DROME | if | genetic | 9250662 | |
ITA2_DROME | if | genetic | 9435290 | |
SLIT_DROME | sli | genetic | 12040052 | |
SRF_DROME | bs | genetic | 9755209 | |
SOG_DROME | sog | physical | 12835400 |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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N-linked Glycosylation | |
Reference | PubMed |
"Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."; Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M.,Schiess R., Aebersold R., Watts J.D.; Nat. Biotechnol. 27:378-386(2009). Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-711; ASN-718 AND ASN-761,AND MASS SPECTROMETRY. | |
"Identification of N-glycosylated proteins from the central nervoussystem of Drosophila melanogaster."; Koles K., Lim J.-M., Aoki K., Porterfield M., Tiemeyer M., Wells L.,Panin V.; Glycobiology 17:1388-1403(2007). Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-657 AND ASN-1027, AND MASSSPECTROMETRY. |